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IHEvsIBBQETF Comparison

ETF 1

IHE

iShares U.S. Pharmaceuticals ETF

This fund is part of

US Health Care

-1.03%

Full IHE fund page

VS

ETF 2

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

-1.03%

Full IBBQ fund page

iShares U.S. Pharmaceuticals ETF (IHE) and Invesco Nasdaq Biotechnology ETF (IBBQ) belong to the same industry segment: US Health Care. IHE's top 2 sector exposures are Healthcare and Non-Corporate. In contrast, IBBQ's top sector exposures are Healthcare and Non-Energy Materials. IHE is more expensive with a Total Expense Ratio (TER) of 0.37%, versus 0.19% for IBBQ. IHE is up 21.99% year-to-date (YTD) with +$500M in YTD flows. IBBQ performs better with 22.86% YTD performance, and +$38M in YTD flows. Run a side-by-side ETF comparison of IHE and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IHE vs IBBQ performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 10/23/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	IHE IBBQ	+1.25%-0.34%	+0.82%+7.21%	+21.99%+22.86%	+39.12%+36.10%	+87.20%+90.27%	+79.04%+44.83%
Flows	IHE IBBQ	-$129M+$14M	+$77M+$35M	+$500M+$38M	+$664M+$56M	+$758M+$74M	+$754M+$52M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	IHE IBBQ	+18.62%+25.52%	+18.66%+22.48%	+17.25%+21.25%	+16.78%+22.22%
Max drawdown	IHE IBBQ	-9.67%-8.58%	-9.67%-8.58%	-16.04%-23.78%	-16.12%-34.86%
Max drawdown duration	IHE IBBQ	65d65d	65d65d	210d375d	669d1429d

Trading data

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	IHE	IBBQ
Last sale 10/23/2026 at 1:30 PM	$102.51	$34.52
Previous close 10/22/2026	$104.78	$34.92
Consolidated volume 10/22/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of September 30, 2026

1-year trailing difference

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	IHE	IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 10/23/2026 at 1:30 PM

Live

Closed

	IHE	IBBQ
Last price	$102.51	$34.52
1D performance	-2.17%	-1.15%
AuM	$1.54 B	$115.07 M
E/R	0.37%	0.19%

Characteristics

	IHE	IBBQ
Management strategy	Passive	Passive
Provider	iShares	Invesco
Benchmark	Dow Jones U.S. Select Pharmaceuticals Index	NASDAQ Biotechnology Index
N° of holdings	57	249
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	May 1, 2006	June 9, 2021
ESG	No	No

More IHE data on Trackinsight

More IBBQ data on Trackinsight

Exposure

Countries

IHE

USA

95.75%

Other

4.25%

IBBQ

USA

88.22%

Other

11.78%

Sectors

IHE

Healthcare

99.75%

Other

0.25%

IBBQ

Healthcare

99.99%

Other

0.01%

Diversification

IHE

Total weight of top 15 holdings out of 15

84.42%

IBBQ

Total weight of top 15 holdings out of 15

52.06%

Top 15 holdings

Data as of August 31, 2026

IHE

Johnson & Johnson

22.45%

Eli Lilly & Co.

20.50%

Merck & Co., Inc.

5.00%

Bristol Myers Squibb Co.

4.84%

Royalty Pharma Plc

4.54%

Pfizer Inc.

4.48%

Viatris, Inc.

4.19%

Zoetis, Inc.

3.82%

Jazz Pharmaceuticals Plc

3.43%

Elanco Animal Health, Inc.

2.61%

Corcept Therapeutics, Inc.

2.36%

Crinetics Pharmaceuticals, Inc.

1.95%

Axsome Therapeutics, Inc.

1.87%

Ligand Pharmaceuticals, Inc.

1.24%

Definium Therapeutics, Inc.

1.12%

IBBQ

Amgen, Inc.

8.60%

Vertex Pharmaceuticals, Inc.

8.10%

Gilead Sciences, Inc.

7.34%

Regeneron Pharmaceuticals, Inc.

5.26%

Moderna, Inc.

3.58%

Revolution Medicines, Inc.

2.97%

Illumina, Inc.

2.18%

Biogen, Inc.

2.07%

Alnylam Pharmaceuticals, Inc.

2.00%

argenx SE

1.84%

Royalty Pharma Plc

1.73%

Roivant Sciences Ltd.

1.71%

Insmed, Inc.

1.66%

Incyte Corp.

1.61%

United Therapeutics Corp.

1.42%

Frequently asked questions about IHE and IBBQ

How have the IHE and IBBQ ETFs performed in 2026?

As of October 23, 2026, IHE is up 21.99% year-to-date (YTD), while IBBQ has returned 22.86%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IHE or IBBQ?

Year-to-date, the IHE ETF saw +$500M in flows, compared to +$38M for IBBQ.

Which ETF is more volatile: IHE or IBBQ?

Over the past year, IHE had a volatility of 18.66%, while IBBQ experienced 22.48%.

Which ETF is bigger: IHE or IBBQ?

As of October 23, 2026, IHE holds $1.54 B in assets under management (AUM), while IBBQ manages $115.07 M.

What sectors do the IHE and IBBQ ETFs invest in?

IHE leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the IHE ETF and IBBQ ETF?

IHE top holdings include Johnson & Johnson, Eli Lilly & Co. and Merck & Co., Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..

IHEvsIBBQETF Comparison

iShares U.S. Pharmaceuticals ETF

Invesco Nasdaq Biotechnology ETF

IHE vs IBBQ performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the IHE and IBBQ ETFs performed in 2026?

As of October 23, 2026, IHE is up 21.99% year-to-date (YTD), while IBBQ has returned 22.86%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: IHE or IBBQ?

Year-to-date, the IHE ETF saw +$500M in flows, compared to +$38M for IBBQ.

Which ETF is more volatile: IHE or IBBQ?

Over the past year, IHE had a volatility of 18.66%, while IBBQ experienced 22.48%.

Which ETF is bigger: IHE or IBBQ?

As of October 23, 2026, IHE holds $1.54 B in assets under management (AUM), while IBBQ manages $115.07 M.

What sectors do the IHE and IBBQ ETFs invest in?

IHE leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the IHE ETF and IBBQ ETF?

IHE top holdings include Johnson & Johnson, Eli Lilly & Co. and Merck & Co., Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..

Which ETF is more diversified: IHE or IBBQ?

IHE holds 57 securities with 84.42% of its assets in the top 15. IBBQ has 249 securities and a top 15 weight of 52.06%.

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