IHEvsFTXHETF Comparison
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iShares U.S. Pharmaceuticals ETF (IHE) and First Trust Nasdaq Pharmaceuticals ETF (FTXH) belong to the same industry segment: US Health Care. IHE's top 2 sector exposures are Healthcare and Non-Corporate. In contrast, FTXH's top sector exposures are Healthcare. IHE is less expensive with a Total Expense Ratio (TER) of 0.37%, versus 0.6% for FTXH. IHE is up 20.21% year-to-date (YTD) with +$599M in YTD flows. FTXH performs better with 24.04% YTD performance, and +$980M in YTD flows. Run a side-by-side ETF comparison of IHE and FTXH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IHE vs FTXH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/10/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IHE FTXH | -2.49%+1.34% | +8.87%+14.39% | +20.21%+24.04% | +44.96%+46.08% | +67.41%+59.12% | +74.30%+67.75% |
| Flows | IHE FTXH | +$22M+$43M | +$607M+$968M | +$599M+$980M | +$756M+$983M | +$848M+$975M | +$853M+$979M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IHE FTXH | +20.04%+20.14% | +18.30%+17.77% | +17.02%+17.00% | +16.58%+16.34% |
| Max drawdown | IHE FTXH | -6.32%-4.79% | -8.48%-7.50% | -16.04%-19.32% | -16.12%-19.32% |
| Max drawdown duration | IHE FTXH | 22d15d | 81d99d | 210d393d | 669d393d |
Trading data
IHE | FTXH | |
Last sale 9/11/2026 at 6:02 PM | $101.23 | $40.54 |
| Previous close 09/10/2026 | $101.27 | $40.52 |
| Consolidated volume 09/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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IHE | FTXH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/11/2026 at 6:02 PM
Live
Closed
IHE | FTXH | |
|---|---|---|
| Last price | $101.23 | $40.54 |
| 1D performance | -0.04% | +0.05% |
| AuM | $1.62 B | $1.05 B |
| E/R | 0.37% | 0.6% |
Characteristics
IHE | FTXH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | iShares | First Trust |
| Benchmark | Dow Jones U.S. Select Pharmaceuticals Index | NASDAQ US Smart Pharmaceuticals Index |
| N° of holdings | 57 | 49 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 1, 2006 | September 20, 2016 |
| ESG | No | No |
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Exposure
Countries
IHE
USA
95.81%
Other
4.19%
FTXH
USA
95.79%
Other
4.21%
Sectors
IHE
Healthcare
99.62%
Other
0.38%
FTXH
Healthcare
99.86%
Other
0.14%
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Diversification
IHE
Total weight of top 15 holdings out of 15
84.32%
FTXH
Total weight of top 15 holdings out of 15
66.98%
Top 15 holdings
Data as of July 31, 2026
IHE
Johnson & Johnson
21.85%
Eli Lilly & Co.
20.71%
Bristol Myers Squibb Co.
4.75%
Viatris, Inc.
4.56%
Merck & Co., Inc.
4.44%
Royalty Pharma Plc
4.41%
Pfizer Inc.
3.96%
Zoetis, Inc.
3.81%
Jazz Pharmaceuticals Plc
3.58%
Elanco Animal Health, Inc.
2.92%
Corcept Therapeutics, Inc.
2.49%
Axsome Therapeutics, Inc.
2.24%
Crinetics Pharmaceuticals, Inc.
1.95%
Liquidia Corp.
1.35%
Ligand Pharmaceuticals, Inc.
1.31%
FTXH
Merck & Co., Inc.
7.58%
Eli Lilly & Co.
7.43%
AbbVie, Inc.
7.11%
Johnson & Johnson
6.78%
Bristol Myers Squibb Co.
6.61%
Amgen, Inc.
3.53%
Biogen, Inc.
3.52%
Vertex Pharmaceuticals, Inc.
3.43%
Viatris, Inc.
3.40%
Regeneron Pharmaceuticals, Inc.
3.34%
Pfizer Inc.
3.17%
Cardinal Health, Inc.
3.14%
Gilead Sciences, Inc.
3.03%
Incyte Corp.
2.48%
United Therapeutics Corp.
2.43%
Frequently asked questions about IHE and FTXH
How have the IHE and FTXH ETFs performed in 2026?
As of September 10, 2026, IHE is up 20.21% year-to-date (YTD), while FTXH has returned 24.04%. That puts FTXH better performer ahead so far this year.
Which ETF is attracting more investor money: IHE or FTXH?
Year-to-date, the IHE ETF saw +$599M in flows, compared to +$980M for FTXH.
Which ETF is more volatile: IHE or FTXH?
Over the past year, IHE had a volatility of 18.3%, while FTXH experienced 17.77%.
Which ETF is bigger: IHE or FTXH?
As of September 10, 2026, IHE holds $1.62 B in assets under management (AUM), while FTXH manages $1.05 B.
What sectors do the IHE and FTXH ETFs invest in?
IHE leans toward sectors like Healthcare. Meanwhile, FTXH focuses on Healthcare.
What are the top holdings of the IHE ETF and FTXH ETF?
IHE top holdings include Johnson & Johnson, Eli Lilly & Co. and Bristol Myers Squibb Co.. FTXH holds in its top three: Merck & Co., Inc., Eli Lilly & Co. and AbbVie, Inc..
Which ETF is more diversified: IHE or FTXH?
IHE holds 57 securities with 84.32% of its assets in the top 15. FTXH has 49 securities and a top 15 weight of 66.98%.
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Latest news about IHE & FTXH
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