IHEvsFTXHETF Comparison
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iShares U.S. Pharmaceuticals ETF (IHE) and First Trust Nasdaq Pharmaceuticals ETF (FTXH) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. IHE is less expensive with a Total Expense Ratio (TER) of 0.38%, versus 0.6% for FTXH. IHE is up 10.98% year-to-date (YTD) with -$7M in YTD flows. FTXH performs worse with 6.85% YTD performance, and +$12M in YTD flows. Run a side-by-side ETF comparison of IHE and FTXH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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IHE vs FTXH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/09/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | IHE FTXH | +7.64%+3.68% | +6.21%+1.74% | +10.98%+6.85% | +43.87%+36.41% | +68.58%+40.67% | +64.51%+47.41% |
| Flows | IHE FTXH | +$100K- | -$145M+$5M | -$7M+$12M | +$126M+$9M | +$223M-$3M | +$256M+$7M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | IHE FTXH | +19.73%+17.68% | +17.31%+16.93% | +16.50%+16.24% | +16.23%+15.91% |
| Max drawdown | IHE FTXH | -5.19%-4.70% | -8.48%-7.50% | -16.04%-19.32% | -16.12%-19.32% |
| Max drawdown duration | IHE FTXH | 37d28d | 81d99d | 210d393d | 669d393d |
Trading data
IHE | FTXH | |
Last sale 6/10/2026 at 1:30 PM | $93.34 | $35.33 |
| Previous close 06/09/2026 | $93.79 | $35.64 |
| Consolidated volume 06/09/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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IHE | FTXH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/10/2026 at 1:30 PM
Live
Closed
IHE | FTXH | |
|---|---|---|
| Last price | $93.34 | $35.33 |
| 1D performance | -0.48% | -0.87% |
| AuM | $933.05 M | $35.13 M |
| E/R | 0.38% | 0.6% |
Characteristics
IHE | FTXH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | iShares | First Trust |
| Benchmark | Dow Jones U.S. Select Pharmaceuticals Index | NASDAQ US Smart Pharmaceuticals Index |
| N° of holdings | 45 | 47 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 1, 2006 | September 20, 2016 |
| ESG | No | No |
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Exposure
Countries
IHE
USA
90.2%
Other
9.8%
FTXH
USA
93.7%
Other
6.3%
Sectors
IHE
Health Care
95.09%
Other
4.91%
FTXH
Health Care
97.61%
Other
2.39%
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Diversification
IHE
Total weight of top 15 holdings out of 15
83.6%
FTXH
Total weight of top 15 holdings out of 15
69.57%
Top 15 holdings
Data as of April 30, 2026
IHE
JOHNSON&JOHNSON
21.40%
LILLY
21.14%
ROYALTY PHARMA
4.85%
VIATRIS INC
4.75%
BRISTOL-MYERS SQUIBB
4.57%
PFIZER
4.42%
ZOETIS INC
4.34%
MERCK & CO INC
4.25%
JAZZ PHARMACEUTICALS
3.40%
ELANCO ANIMAL HEALTH INC
3.07%
AXSOME THERA CMN STK
2.43%
US45579U1097
1.27%
TERNS PHARMACEUTICALS
1.26%
LIGAND PHARMACEUTICALS
1.25%
CORCEPT THERAPEUTICS
1.20%
FTXH
BRISTOL-MYERS SQUIBB
7.25%
JOHNSON&JOHNSON
7.12%
MERCK & CO INC
6.90%
ABBVIE
6.61%
LILLY
6.45%
VIATRIS INC
3.85%
PFIZER
3.72%
BIOGEN INC
3.71%
REGENERON PHARMACEUTICALS
3.63%
CARDINAL HEALTH
3.48%
ZOETIS INC
3.45%
AMGEN-T
3.40%
GILEAD SCIENCES
3.37%
VERTEX PHARMACEUTICALS
3.36%
UTD THERAPEUT
3.26%
Frequently asked questions about IHE and FTXH
How have the IHE and FTXH ETFs performed in 2026?
As of June 9, 2026, IHE is up 10.98% year-to-date (YTD), while FTXH has returned 6.85%. That puts IHE better performer ahead so far this year.
Which ETF is attracting more investor money: IHE or FTXH?
Year-to-date, the IHE ETF saw -$7M in flows, compared to +$12M for FTXH.
Which ETF is more volatile: IHE or FTXH?
Over the past year, IHE had a volatility of 17.31%, while FTXH experienced 16.93%.
Which ETF is bigger: IHE or FTXH?
As of June 9, 2026, IHE holds $933.05 M in assets under management (AUM), while FTXH manages $35.13 M.
What sectors do the IHE and FTXH ETFs invest in?
IHE leans toward sectors like Health Care. Meanwhile, FTXH focuses on Health Care.
What are the top holdings of the IHE ETF and FTXH ETF?
IHE top holdings include JOHNSON&JOHNSON, LILLY and ROYALTY PHARMA. FTXH holds in its top three: BRISTOL-MYERS SQUIBB, JOHNSON&JOHNSON and MERCK & CO INC.
Which ETF is more diversified: IHE or FTXH?
IHE holds 57 securities with 83.6% of its assets in the top 15. FTXH has 47 securities and a top 15 weight of 69.57%.
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