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IBBQvsIHEETF Comparison

ETF 1
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-0.31%
Full IBBQ fund page
VS
ETF 2
IHE

iShares U.S. Pharmaceuticals ETF

This fund is part of
US Health Care
-0.31%
Full IHE fund page

Invesco Nasdaq Biotechnology ETF (IBBQ) and iShares U.S. Pharmaceuticals ETF (IHE) belong to the same industry segment: US Health Care. IBBQ's top 3 sector exposures are Health Care and Consumer Staples. In contrast, IHE's top sector exposures are Health Care  IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.38% for IHE. IBBQ is up 3.54% year-to-date (YTD) with +$8M in YTD flows. IHE performs better with 4.3% YTD performance, and +$129M in YTD flows. Run a side-by-side ETF comparison of IBBQ and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IBBQ vs IHE performance and flow charts

Performance

-3.0-2.0-1.00.01.02.0%Feb 11Feb 19Feb 26Mar 5

Cumulative Flows

0 M5 M10 M15 M20 MFeb 11Feb 19Feb 26Mar 5

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Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
IBBQ
IHE
-0.23%-1.82%
+3.22%+5.93%
+3.54%+4.30%
+33.90%+28.47%
+50.91%+63.32%
n/a+61.21%
Flows
IBBQ
IHE
+$2M+$9M
+$13M+$154M
+$8M+$129M
+$21M+$248M
+$41M+$359M
-+$393M
Volatility and drawdown
3M1Y3Y5Y
Volatility
IBBQ
IHE
+19.87%+15.86%
+22.98%+20.40%
+19.25%+15.94%
n/a+15.80%
Max drawdown
IBBQ
IHE
-4.51%-4.49%
-17.24%-14.18%
-23.78%-16.04%
n/a-16.12%
Max drawdown duration
IBBQ
IHE
15d10d
127d150d
375d210d
n/a669d
Trading data

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IBBQ
IHE
Last sale
3/11/2026 at 7:59 PM
$29.38
$86.70
Previous close
03/11/2026
$29.56
$88.40
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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IBBQ
IHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/11/2026 at 7:59 PM
Live
Closed
IBBQ
IHE
Last price
$29.38
$86.70
1D performance
-0.61%
-1.92%
AuM$74.04 M$1.02 B
E/R0.19%0.38%
Characteristics
IBBQ
IHE
Management strategyPassivePassive
ProviderInvescoiShares
BenchmarkNASDAQ Biotechnology IndexDow Jones U.S. Select Pharmaceuticals Index
N° of holdings19646
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateJune 9, 2021May 1, 2006
ESGNoNo
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Exposure

Countries

IBBQ
USA
93.84%
Other
6.16%
IHE
USA
90.92%
Other
9.08%

Sectors

IBBQ
Health Care
85.82%
Other
14.18%
IHE
Health Care
96.19%
Other
3.81%
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Diversification

IBBQ

Total weight of top 15 holdings out of 15

52.08%
IHE

Total weight of top 15 holdings out of 15

84.8%

Top 15 holdings

Data as of January 31, 2026
IBBQ
VERTEX PHARMACEUTICALS
8.96%
GILEAD SCIENCES
8.92%
AMGEN-T
8.25%
REGENERON PHARMACEUTICALS
5.90%
ALNYLAM PHARMACEUTICALS
3.58%
INSMED
2.55%
BIOGEN INC
1.90%
US04016X1019
1.82%
ILLUMINA
1.75%
UTD THERAPEUT
1.53%
INCYTE
1.51%
REVOLUTION MEDICINES INC
1.42%
MODERNA INC
1.41%
ROYALTY PHARMA
1.30%
MEDPACE HOLDINGS INC
1.27%
IHE
JOHNSON&JOHNSON
23.72%
LILLY
22.21%
MERCK & CO INC
4.78%
BRISTOL-MYERS SQUIBB
4.57%
ZOETIS INC
4.44%
PFIZER
4.36%
ROYALTY PHARMA
4.08%
VIATRIS INC
4.00%
ELANCO ANIMAL HEALTH INC
3.20%
JAZZ PHARMACEUTICALS
2.65%
AXSOME THERA CMN STK
2.09%
CRINETICS PHARMACEUTICALS
1.41%
US45579U1097
1.15%
CORCEPT THERAPEUTICS
1.11%
LIGAND PHARMACEUTICALS
1.02%
Frequently asked questions about IBBQ and IHE

How have the IBBQ and IHE ETFs performed in 2026?

As of March 11, 2026, IBBQ is up 3.54% year-to-date (YTD), while IHE has returned 4.3%. That puts IHE better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or IHE?

Year-to-date, the IBBQ ETF saw +$8M in flows, compared to +$129M for IHE.

Which ETF is more volatile: IBBQ or IHE?

Over the past year, IBBQ had a volatility of 22.98%, while IHE experienced 20.4%.

Which ETF is bigger: IBBQ or IHE?

As of March 11, 2026, IBBQ holds $74.04 M in assets under management (AUM), while IHE manages $1.02 B.

What sectors do the IBBQ and IHE ETFs invest in?

IBBQ leans toward sectors like Health Care. Meanwhile, IHE focuses on Health Care.

What are the top holdings of the IBBQ ETF and IHE ETF?

IBBQ top holdings include VERTEX PHARMACEUTICALS, GILEAD SCIENCES and AMGEN-T. IHE holds in its top three: JOHNSON&JOHNSON, LILLY and MERCK & CO INC.

Which ETF is more diversified: IBBQ or IHE?

IBBQ holds 262 securities with 52.08% of its assets in the top 15. IHE has 56 securities and a top 15 weight of 84.8%.

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