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IBBQvsIHEETF Comparison

ETF 1

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

+1.78%

Full IBBQ fund page

VS

ETF 2

IHE

iShares U.S. Pharmaceuticals ETF

This fund is part of

US Health Care

+1.78%

Full IHE fund page

Invesco Nasdaq Biotechnology ETF (IBBQ) and iShares U.S. Pharmaceuticals ETF (IHE) belong to the same industry segment: US Health Care. IBBQ's top 3 sector exposures are Healthcare and Non-Energy Materials. In contrast, IHE's top sector exposures are Healthcare and Non-Corporate. IBBQ is less expensive with a Total Expense Ratio (TER) of 0.19%, versus 0.38% for IHE. IBBQ is up 15.65% year-to-date (YTD) with +$3M in YTD flows. IHE performs better with 23.45% YTD performance, and +$578M in YTD flows. Run a side-by-side ETF comparison of IBBQ and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IBBQ vs IHE performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 07/28/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	IBBQ IHE	+0.34%+3.87%	+13.13%+21.63%	+15.65%+23.45%	+47.33%+54.16%	+62.62%+78.34%	+31.41%+76.15%
Flows	IBBQ IHE	+$4M+$465M	+$3M+$496M	+$3M+$578M	+$23M+$731M	+$39M+$826M	+$3M+$841M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	IBBQ IHE	+22.64%+21.18%	+20.25%+18.06%	+20.25%+16.92%	+21.96%+16.50%
Max drawdown	IBBQ IHE	-5.97%-4.42%	-8.38%-8.48%	-23.78%-16.04%	-38.09%-16.12%
Max drawdown duration	IBBQ IHE	21d20d	48d81d	375d210d	1543d669d

Trading data

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	IBBQ	IHE
Last sale 7/29/2026 at 1:30 PM	$32.41	$103.50
Previous close 07/28/2026	$32.76	$103.96
Consolidated volume 07/28/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of June 30, 2026

1-year trailing difference

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	IBBQ	IHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 7/29/2026 at 1:30 PM

Live

Closed

	IBBQ	IHE
Last price	$32.41	$103.50
1D performance	-1.06%	-0.44%
AuM	$76.61 M	$1.64 B
E/R	0.19%	0.38%

Characteristics

	IBBQ	IHE
Management strategy	Passive	Passive
Provider	Invesco	iShares
Benchmark	NASDAQ Biotechnology Index	Dow Jones U.S. Select Pharmaceuticals Index
N° of holdings	251	57
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 9, 2021	May 1, 2006
ESG	No	No

More IBBQ data on Trackinsight

More IHE data on Trackinsight

Exposure

Countries

IBBQ

USA

88.1%

Other

11.9%

IHE

USA

96.01%

Other

3.99%

Sectors

IBBQ

Healthcare

99.98%

Other

0.02%

IHE

Healthcare

99.92%

Other

0.08%

Diversification

IBBQ

Total weight of top 15 holdings out of 15

49.38%

IHE

Total weight of top 15 holdings out of 15

84.53%

Top 15 holdings

Data as of June 30, 2026

IBBQ

Vertex Pharmaceuticals, Inc.

8.16%

Amgen, Inc.

7.91%

Gilead Sciences, Inc.

7.07%

Regeneron Pharmaceuticals, Inc.

4.62%

Alnylam Pharmaceuticals, Inc.

2.76%

Revolution Medicines, Inc.

2.74%

Biogen, Inc.

2.26%

Illumina, Inc.

1.89%

Moderna, Inc.

1.89%

Royalty Pharma Plc

1.77%

Roivant Sciences Ltd.

1.74%

argenx SE

1.73%

United Therapeutics Corp.

1.63%

Incyte Corp.

1.61%

Insmed, Inc.

1.59%

IHE

Johnson & Johnson

22.44%

Eli Lilly & Co.

22.25%

Merck & Co., Inc.

4.55%

Bristol Myers Squibb Co.

4.37%

Royalty Pharma Plc

4.33%

Viatris, Inc.

4.22%

Pfizer Inc.

3.96%

Zoetis, Inc.

3.73%

Jazz Pharmaceuticals Plc

3.45%

Elanco Animal Health, Inc.

2.81%

Axsome Therapeutics, Inc.

2.41%

Corcept Therapeutics, Inc.

1.90%

Ligand Pharmaceuticals, Inc.

1.45%

Definium Therapeutics, Inc.

1.39%

Liquidia Corp.

1.28%

Frequently asked questions about IBBQ and IHE

How have the IBBQ and IHE ETFs performed in 2026?

As of July 28, 2026, IBBQ is up 15.65% year-to-date (YTD), while IHE has returned 23.45%. That puts IHE better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or IHE?

Year-to-date, the IBBQ ETF saw +$3M in flows, compared to +$578M for IHE.

Which ETF is more volatile: IBBQ or IHE?

Over the past year, IBBQ had a volatility of 20.25%, while IHE experienced 18.06%.

Which ETF is bigger: IBBQ or IHE?

As of July 28, 2026, IBBQ holds $76.61 M in assets under management (AUM), while IHE manages $1.64 B.

What sectors do the IBBQ and IHE ETFs invest in?

IBBQ leans toward sectors like Healthcare. Meanwhile, IHE focuses on Healthcare.

What are the top holdings of the IBBQ ETF and IHE ETF?

IBBQ top holdings include Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc.. IHE holds in its top three: Johnson & Johnson, Eli Lilly & Co. and Merck & Co., Inc..

IBBQvsIHEETF Comparison

Invesco Nasdaq Biotechnology ETF

iShares U.S. Pharmaceuticals ETF

IBBQ vs IHE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the IBBQ and IHE ETFs performed in 2026?

As of July 28, 2026, IBBQ is up 15.65% year-to-date (YTD), while IHE has returned 23.45%. That puts IHE better performer ahead so far this year.

Which ETF is attracting more investor money: IBBQ or IHE?

Year-to-date, the IBBQ ETF saw +$3M in flows, compared to +$578M for IHE.

Which ETF is more volatile: IBBQ or IHE?

Over the past year, IBBQ had a volatility of 20.25%, while IHE experienced 18.06%.

Which ETF is bigger: IBBQ or IHE?

As of July 28, 2026, IBBQ holds $76.61 M in assets under management (AUM), while IHE manages $1.64 B.

What sectors do the IBBQ and IHE ETFs invest in?

IBBQ leans toward sectors like Healthcare. Meanwhile, IHE focuses on Healthcare.

What are the top holdings of the IBBQ ETF and IHE ETF?

IBBQ top holdings include Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc.. IHE holds in its top three: Johnson & Johnson, Eli Lilly & Co. and Merck & Co., Inc..

Which ETF is more diversified: IBBQ or IHE?

IBBQ holds 251 securities with 49.38% of its assets in the top 15. IHE has 57 securities and a top 15 weight of 84.53%.

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