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HRTSvsPBPHETF Comparison

ETF 1

HRTS

Tema GLP-1, Obesity & Cardiometabolic ETF

This fund is part of

Tomorrow's Treatments

-1.28%

Full HRTS fund page

VS

ETF 2

PBPH

Portfolio Building Block World Pharma and Biotech Index ETF

This fund is part of

DM Large & Mid Cap

-0.57%

Full PBPH fund page

Tema GLP-1, Obesity & Cardiometabolic ETF (HRTS) belongs to the Tomorrow's Treatments segment. Portfolio Building Block World Pharma and Biotech Index ETF (PBPH) is part of the DM Large & Mid Cap segment. Both ETFs have the same top 3 sector exposures: and Health Care. HRTS is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.13% for PBPH. HRTS is down -7.09% year-to-date (YTD) with -$2M in YTD flows. PBPH performs better with -2.73% YTD performance, and +$787M in YTD flows. Run a side-by-side ETF comparison of HRTS and PBPH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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HRTS vs PBPH performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/29/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	HRTS PBPH	+0.22%-1.83%	-7.83%-5.37%	-7.09%-2.73%	+15.13%n/a	n/an/a	n/an/a
Flows	HRTS PBPH	-$1M+$39M	-$4M+$757M	-$2M+$787M	-$12M-	--	--

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	HRTS PBPH	+16.39%+16.32%	+16.33%n/a	n/an/a	n/an/a
Max drawdown	HRTS PBPH	-9.68%-9.94%	-10.68%n/a	n/an/a	n/an/a
Max drawdown duration	HRTS PBPH	59d70d	112dn/a	n/an/a	n/an/a

Trading data

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	HRTS	PBPH
Last sale 4/29/2026 at 6:04 PM	$32.74	$25.10
Previous close 04/29/2026	$33.15	$24.30
Consolidated volume 04/29/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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HRTS

is actively managed and doesn’t replicate an index

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	HRTS	PBPH
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/29/2026 at 6:04 PM

Live

Closed

	HRTS	PBPH
Last price	$32.74	$25.10
1D performance	-1.22%	+3.30%
AuM	$48.91 M	$725.81 M
E/R	0.99%	0.13%

Characteristics

	HRTS	PBPH
Management strategy	Active	Passive
Provider	Tema	Tidal
Benchmark	-	BITA Global Pharma and Biotech Select Index
N° of holdings	38	49
Asset class	-	-
Trailing 12m distribution yield	Join	Join
Inception date	November 21, 2023	November 24, 2025
ESG	No	No

More HRTS data on Trackinsight

More PBPH data on Trackinsight

Exposure

Countries

HRTS

USA

82.47%

Other

17.53%

PBPH

USA

63.05%

Switzerland

10.48%

Other

26.47%

Sectors

HRTS

Health Care

87.86%

Other

12.14%

PBPH

Health Care

85.65%

Other

14.35%

Diversification

HRTS

Total weight of top 15 holdings out of 15

61.52%

PBPH

Total weight of top 15 holdings out of 15

71.34%

Top 15 holdings

Data as of March 31, 2026

HRTS

LILLY

9.70%

JOHNSON&JOHNSON

4.97%

US7711951043

4.94%

ASTRAZENECA

4.91%

MERCK & CO INC

4.46%

THERMO FISHER SCIENTIFIC

4.06%

UNITEDHEALTH GRP

3.79%

GILEAD SCIENCES

3.66%

NOVARTIS

3.52%

VERTEX PHARMACEUTICALS

3.30%

ABBOTT LABS

3.26%

ABBVIE

3.00%

BRIDGEBIO PHARMA

2.85%

DANAHER

2.81%

BRISTOL-MYERS SQUIBB

2.29%

PBPH

LILLY

12.31%

JOHNSON&JOHNSON

9.59%

ABBVIE

6.19%

MERCK & CO INC

4.79%

NOVARTIS

4.64%

CH1499059983

4.47%

GILEAD SCIENCES

4.42%

AMGEN-T

4.38%

PFIZER

4.13%

BRISTOL-MYERS SQUIBB

3.18%

DK0062498333

2.96%

VERTEX PHARMACEUTICALS

2.94%

SANOFI SA

2.68%

GSK PLC

2.67%

REGENERON PHARMACEUTICALS

2.00%

Frequently asked questions about HRTS and PBPH

How have the HRTS and PBPH ETFs performed in 2026?

As of April 29, 2026, HRTS is down -7.09% year-to-date (YTD), while PBPH has lost -2.73%. That puts PBPH better performer ahead so far this year.

Which ETF is attracting more investor money: HRTS or PBPH?

Year-to-date, the HRTS ETF saw -$2M in flows, compared to +$787M for PBPH.

Which ETF is bigger: HRTS or PBPH?

As of April 29, 2026, HRTS holds $48.91 M in assets under management (AUM), while PBPH manages $725.81 M.

What sectors do the HRTS and PBPH ETFs invest in?

HRTS leans toward sectors like Health Care. Meanwhile, PBPH focuses on Health Care.

What are the top holdings of the HRTS ETF and PBPH ETF?

HRTS top holdings include LILLY, JOHNSON&JOHNSON and US7711951043. PBPH holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.

Which ETF is more diversified: HRTS or PBPH?

HRTS holds 44 securities with 61.52% of its assets in the top 15. PBPH has 52 securities and a top 15 weight of 71.34%.

A Deep Dive into the New Amplify Weight Loss Drug & Treatment ETF (THNR)

June 7, 2024

HRTS

Obesity and Weight-Loss Drugs: A New Thematic ETF Segment?

April 18, 2024

HRTS

HRTSvsPBPHETF Comparison

Tema GLP-1, Obesity & Cardiometabolic ETF

Portfolio Building Block World Pharma and Biotech Index ETF

HRTS vs PBPH performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the HRTS and PBPH ETFs performed in 2026?

As of April 29, 2026, HRTS is down -7.09% year-to-date (YTD), while PBPH has lost -2.73%. That puts PBPH better performer ahead so far this year.

Which ETF is attracting more investor money: HRTS or PBPH?

Year-to-date, the HRTS ETF saw -$2M in flows, compared to +$787M for PBPH.

Which ETF is bigger: HRTS or PBPH?

As of April 29, 2026, HRTS holds $48.91 M in assets under management (AUM), while PBPH manages $725.81 M.

What sectors do the HRTS and PBPH ETFs invest in?

HRTS leans toward sectors like Health Care. Meanwhile, PBPH focuses on Health Care.

What are the top holdings of the HRTS ETF and PBPH ETF?

HRTS top holdings include LILLY, JOHNSON&JOHNSON and US7711951043. PBPH holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.

Which ETF is more diversified: HRTS or PBPH?

HRTS holds 44 securities with 61.52% of its assets in the top 15. PBPH has 52 securities and a top 15 weight of 71.34%.

A Deep Dive into the New Amplify Weight Loss Drug & Treatment ETF (THNR)

Obesity and Weight-Loss Drugs: A New Thematic ETF Segment?

Active Trader Report: Use of Leveraged & Inverse ETFs Way Up