HRTSvsIYHETF Comparison
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Tema GLP-1, Obesity & Cardiometabolic ETF (HRTS) belongs to the Tomorrow's Treatments segment. iShares U.S. Healthcare ETF (IYH) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. HRTS is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.38% for IYH. HRTS is down -2.91% year-to-date (YTD) with -$1M in YTD flows. IYH performs better with -0.6% YTD performance, and -$393M in YTD flows. Run a side-by-side ETF comparison of HRTS and IYH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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HRTS vs IYH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | HRTS IYH | +1.69%+5.09% | +1.34%+3.25% | -2.91%-0.60% | +19.31%+14.15% | n/a+21.35% | n/a+26.84% |
| Flows | HRTS IYH | +$344K+$194M | -$339K+$103M | -$1M-$393M | -$10M-$14M | --$512M | -+$30M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | HRTS IYH | +17.41%+16.35% | +15.73%+15.18% | n/a+14.20% | n/a+14.98% |
| Max drawdown | HRTS IYH | -5.26%-4.62% | -10.68%-10.72% | n/a-17.89% | n/a-17.89% |
| Max drawdown duration | HRTS IYH | 54d66d | 156d156d | n/a445d | n/a445d |
Trading data
HRTS | IYH | |
Last sale 6/12/2026 at 7:41 PM | $34.26 | $64.18 |
| Previous close 06/12/2026 | $34.44 | $64.48 |
| Consolidated volume 06/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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HRTS
is actively managed and doesn’t replicate an indexHRTS | IYH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 7:41 PM
Live
Closed
HRTS | IYH | |
|---|---|---|
| Last price | $34.26 | $64.18 |
| 1D performance | -0.51% | -0.47% |
| AuM | $52.14 M | $3.15 B |
| E/R | 0.99% | 0.38% |
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Exposure
Countries
HRTS
USA
81.88%
Other
18.12%
IYH
USA
96.67%
Other
3.33%
Sectors
HRTS
Health Care
86.6%
Other
13.4%
IYH
Health Care
97.93%
Other
2.07%
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Diversification
HRTS
Total weight of top 15 holdings out of 15
61.36%
IYH
Total weight of top 15 holdings out of 15
68.52%
Top 15 holdings
Data as of April 30, 2026
HRTS
LILLY
9.40%
UNITEDHEALTH GRP
5.08%
US7711951043
4.92%
ASTRAZENECA
4.23%
JOHNSON&JOHNSON
4.23%
MERCK & CO INC
4.12%
DK0062498333
3.96%
THERMO FISHER SCIENTIFIC
3.92%
GILEAD SCIENCES
3.39%
NOVARTIS
3.38%
VERTEX PHARMACEUTICALS
3.14%
BRIDGEBIO PHARMA
3.03%
ABBOTT LABS
2.93%
REVOLUTION MEDICINES INC
2.89%
ABBVIE
2.74%
IYH
LILLY
13.72%
JOHNSON&JOHNSON
10.14%
ABBVIE
6.86%
UNITEDHEALTH GRP
6.18%
MERCK & CO INC
4.97%
AMGEN-T
3.41%
THERMO FISHER SCIENTIFIC
3.32%
GILEAD SCIENCES
2.99%
INTUITIVE SURGICAL
2.96%
ABBOTT LABS
2.88%
PFIZER
2.78%
BRISTOL-MYERS SQUIBB
2.26%
DANAHER
2.07%
STRYKER
1.99%
VERTEX PHARMACEUTICALS
1.99%
Frequently asked questions about HRTS and IYH
How have the HRTS and IYH ETFs performed in 2026?
As of June 12, 2026, HRTS is down -2.91% year-to-date (YTD), while IYH has lost -0.6%. That puts IYH better performer ahead so far this year.
Which ETF is attracting more investor money: HRTS or IYH?
Year-to-date, the HRTS ETF saw -$1M in flows, compared to -$393M for IYH.
Which ETF is more volatile: HRTS or IYH?
Over the past year, HRTS had a volatility of 15.73%, while IYH experienced 15.18%.
Which ETF is bigger: HRTS or IYH?
As of June 12, 2026, HRTS holds $52.14 M in assets under management (AUM), while IYH manages $3.15 B.
What sectors do the HRTS and IYH ETFs invest in?
HRTS leans toward sectors like Health Care. Meanwhile, IYH focuses on Health Care.
What are the top holdings of the HRTS ETF and IYH ETF?
HRTS top holdings include LILLY, UNITEDHEALTH GRP and US7711951043. IYH holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.
Which ETF is more diversified: HRTS or IYH?
HRTS holds 43 securities with 61.36% of its assets in the top 15. IYH has 104 securities and a top 15 weight of 68.52%.
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Latest news about HRTS & IYH
Obesity and Weight-Loss Drugs: A New Thematic ETF Segment?
April 18, 2024
HRTS
Health Care Sector Down After a Cyberattack on UnitedHealth
March 4, 2024
IYH
Healthcare Stocks Rebound
August 14, 2023
IYH
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Continued tightening of the U.S. labor market
September 23, 2022
IYH
Continued tightening of the U.S. labor market
September 23, 2022
IYH
U.S. labor market facing tight conditions
July 5, 2022
IYH
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