Keep tabs on your favorite ETFs with a personalized weekly tracker. Create a Watchlist now →
GNOMvsXPHETF Comparison
Global X Genomics & Biotechnology ETF - USD (GNOM) belongs to the BioTech & Genomics segment. SPDR S&P Pharmaceuticals ETF (XPH) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. GNOM is more expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.35% for XPH. GNOM is down -0.99% year-to-date (YTD) with -$2M in YTD flows. XPH performs worse with -1.12% YTD performance, and +$88M in YTD flows. Run a side-by-side ETF comparison of GNOM and XPH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
GNOM vs XPH performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | GNOM XPH | -2.35%-3.45% | -3.29%-1.36% | -0.99%-1.12% | +29.80%+29.22% | -6.02%+42.98% | -51.80%+9.16% |
| Flows | GNOM XPH | -+$12M | -$4M+$95M | -$2M+$88M | -$19M+$111M | -$115M+$48M | +$11M+$36M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | GNOM XPH | +23.45%+20.33% | +30.08%+23.08% | +28.53%+19.01% | +33.47%+20.26% |
| Max drawdown | GNOM XPH | -10.89%-5.97% | -22.14%-17.10% | -46.50%-23.45% | -72.17%-33.10% |
| Max drawdown duration | GNOM XPH | 48d14d | 113d140d | 1031d322d | 1714d1706d |
GNOM | XPH | |
Last sale 3/12/2026 at 1:30 PM | $43.61 | $53.64 |
| Previous close 03/11/2026 | $45.00 | $55.49 |
| Consolidated volume 03/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Create an account to view replication metrics
GNOM | XPH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
GNOM | XPH | |
|---|---|---|
| Last price | $43.61 | $53.64 |
| 1D performance | -3.09% | -3.33% |
| AuM | $49.36 M | $313.37 M |
| E/R | 0.5% | 0.35% |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the GNOM and XPH ETFs performed in 2026?
As of March 11, 2026, GNOM is down -0.99% year-to-date (YTD), while XPH has lost -1.12%. That puts GNOM better performer ahead so far this year.
Which ETF is attracting more investor money: GNOM or XPH?
Year-to-date, the GNOM ETF saw -$2M in flows, compared to +$88M for XPH.
Which ETF is more volatile: GNOM or XPH?
Over the past year, GNOM had a volatility of 30.08%, while XPH experienced 23.08%.
Which ETF is bigger: GNOM or XPH?
As of March 11, 2026, GNOM holds $49.36 M in assets under management (AUM), while XPH manages $313.37 M.
What sectors do the GNOM and XPH ETFs invest in?
GNOM leans toward sectors like Health Care. Meanwhile, XPH focuses on Health Care.
What are the top holdings of the GNOM ETF and XPH ETF?
GNOM top holdings include MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070. XPH holds in its top three: LIQUIDIA CORPORATION, US55287L1017 and AXSOME THERA CMN STK.
Which ETF is more diversified: GNOM or XPH?
GNOM holds 48 securities with 63.95% of its assets in the top 15. XPH has 57 securities and a top 15 weight of 32.4%.
Donald Trump’s Executive Orders: ETF Bulls and Bears
Analyzing the Potential ETF Winners & Losers from The Weight-Loss Drug Craze
Have you tried our ETF Compare tool?
Compare ETFs like a pro. Analyze fees, performance, exposure & holdings side-by-side.