FXHvsIHEETF Comparison
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First Trust Health Care AlphaDEX Fund ETF (FXH) and iShares U.S. Pharmaceuticals ETF (IHE) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. FXH is more expensive with a Total Expense Ratio (TER) of 0.61%, versus 0.38% for IHE. FXH is down -1.02% year-to-date (YTD) with -$56M in YTD flows. IHE performs better with 0.36% YTD performance, and +$68M in YTD flows. Run a side-by-side ETF comparison of FXH and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FXH vs IHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/28/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FXH IHE | +6.72%+0.73% | -2.22%-1.40% | -1.02%+0.36% | +14.25%+27.46% | +4.49%+46.45% | -1.02%+54.17% |
| Flows | FXH IHE | +$354K-$61M | -$62M-$33M | -$56M+$68M | -$118M+$199M | -$713M+$299M | -$500M+$332M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FXH IHE | +17.09%+18.53% | +16.22%+17.93% | +15.23%+16.13% | +16.68%+16.00% |
| Max drawdown | FXH IHE | -9.86%-8.48% | -12.07%-9.18% | -17.89%-16.04% | -29.40%-16.12% |
| Max drawdown duration | FXH IHE | 58d59d | 111d82d | 331d210d | 1695d669d |
Trading data
FXH | IHE | |
Last sale 4/30/2026 at 1:30 PM | $112.93 | $87.63 |
| Previous close 04/29/2026 | $111.91 | $84.82 |
| Consolidated volume 04/29/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of April 29, 2026
1-year trailing difference
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FXH | IHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/30/2026 at 1:30 PM
Live
Closed
FXH | IHE | |
|---|---|---|
| Last price | $112.93 | $87.63 |
| 1D performance | +0.91% | +3.31% |
| AuM | $870.97 M | $915.85 M |
| E/R | 0.61% | 0.38% |
Characteristics
FXH | IHE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | StrataQuant Health Care Index | Dow Jones U.S. Select Pharmaceuticals Index |
| N° of holdings | 71 | 45 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | May 8, 2007 | May 1, 2006 |
| ESG | No | No |
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Exposure
Countries
FXH
USA
95.47%
Other
4.53%
IHE
USA
90.65%
Other
9.35%
Sectors
FXH
Health Care
93.76%
Other
6.24%
IHE
Health Care
95.58%
Other
4.42%
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Diversification
FXH
Total weight of top 15 holdings out of 15
35.37%
IHE
Total weight of top 15 holdings out of 15
84.72%
Top 15 holdings
Data as of March 31, 2026
FXH
ACADIA HEALTHCARE COMPANY
3.83%
APELLIS PHARMACEUTICALS
2.95%
PFIZER
2.63%
BIOGEN INC
2.40%
CARDINAL HEALTH
2.37%
HCA HEALTHCARE
2.33%
INCYTE
2.19%
IONIS PHARMACEUTICALS INC
2.18%
INSMED
2.17%
UTD THERAPEUT
2.15%
MERCK & CO INC
2.11%
NATERA
2.04%
LILLY
2.04%
MEDPACE HOLDINGS INC
2.00%
AMGEN-T
1.98%
IHE
JOHNSON&JOHNSON
23.02%
LILLY
21.05%
MERCK & CO INC
4.74%
PFIZER
4.71%
ROYALTY PHARMA
4.70%
BRISTOL-MYERS SQUIBB
4.63%
ZOETIS INC
4.52%
VIATRIS INC
4.35%
ELANCO ANIMAL HEALTH INC
3.32%
JAZZ PHARMACEUTICALS
3.21%
AXSOME THERA CMN STK
2.00%
TERNS PHARMACEUTICALS
1.27%
LIGAND PHARMACEUTICALS
1.10%
US45579U1097
1.06%
CORCEPT THERAPEUTICS
1.05%
Frequently asked questions about FXH and IHE
How have the FXH and IHE ETFs performed in 2026?
As of April 28, 2026, FXH is down -1.02% year-to-date (YTD), while IHE has returned 0.36%. That puts IHE better performer ahead so far this year.
Which ETF is attracting more investor money: FXH or IHE?
Year-to-date, the FXH ETF saw -$56M in flows, compared to +$68M for IHE.
Which ETF is more volatile: FXH or IHE?
Over the past year, FXH had a volatility of 16.22%, while IHE experienced 17.93%.
Which ETF is bigger: FXH or IHE?
As of April 28, 2026, FXH holds $870.97 M in assets under management (AUM), while IHE manages $915.85 M.
What sectors do the FXH and IHE ETFs invest in?
FXH leans toward sectors like Health Care. Meanwhile, IHE focuses on Health Care.
What are the top holdings of the FXH ETF and IHE ETF?
FXH top holdings include ACADIA HEALTHCARE COMPANY, APELLIS PHARMACEUTICALS and PFIZER. IHE holds in its top three: JOHNSON&JOHNSON, LILLY and MERCK & CO INC.
Which ETF is more diversified: FXH or IHE?
FXH holds 75 securities with 35.37% of its assets in the top 15. IHE has 57 securities and a top 15 weight of 84.72%.
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