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FTXHvsIHEETF Comparison

ETF 1
FTXH

First Trust Nasdaq Pharmaceuticals ETF

This fund is part of
US Health Care
-2%
Full FTXH fund page
VS
ETF 2
IHE

iShares U.S. Pharmaceuticals ETF

This fund is part of
US Health Care
-2%
Full IHE fund page

First Trust Nasdaq Pharmaceuticals ETF (FTXH) and iShares U.S. Pharmaceuticals ETF (IHE) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. FTXH is more expensive with a Total Expense Ratio (TER) of 0.6%, versus 0.38% for IHE. FTXH is up 2.6% year-to-date (YTD) with +$7M in YTD flows. IHE performs worse with 2.22% YTD performance, and +$129M in YTD flows. Run a side-by-side ETF comparison of FTXH and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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FTXH vs IHE performance and flow charts

Performance

-4.0-3.0-2.0-1.00.01.02.0%Feb 12Feb 20Feb 27Mar 6

Cumulative Flows

0 M5 M10 M15 M20 MFeb 12Feb 20Feb 27Mar 6

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Historic performance and flows
Data as of 03/12/2026
1M3MYTD1Y3Y5Y
Perf.
FTXH
IHE
-2.89%-3.87%
+3.86%+2.93%
+2.60%+2.22%
+22.74%+27.13%
+39.72%+60.07%
+37.82%+57.13%
Flows
FTXH
IHE
+$4M+$9M
+$9M+$146M
+$7M+$129M
+$10M+$248M
-$13M+$359M
+$7M+$393M
Volatility and drawdown
3M1Y3Y5Y
Volatility
FTXH
IHE
+15.86%+16.35%
+20.64%+20.48%
+15.91%+15.97%
+15.69%+15.82%
Max drawdown
FTXH
IHE
-5.21%-5.64%
-16.42%-14.18%
-19.32%-16.04%
-19.32%-16.12%
Max drawdown duration
FTXH
IHE
11d11d
165d150d
393d210d
393d669d
Trading data

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FTXH
IHE
Last sale
3/13/2026 at 1:30 PM
$33.63
$86.56
Previous close
03/12/2026
$33.78
$86.66
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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FTXH
IHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
FTXH
IHE
Last price
$33.63
$86.56
1D performance
-0.45%
-0.12%
AuM$28.72 M$996.54 M
E/R0.6%0.38%
Characteristics
FTXH
IHE
Management strategyPassivePassive
ProviderFirst TrustiShares
BenchmarkNASDAQ US Smart Pharmaceuticals IndexDow Jones U.S. Select Pharmaceuticals Index
N° of holdings4946
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateSeptember 20, 2016May 1, 2006
ESGNoNo
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Exposure

Countries

FTXH
USA
95.63%
Other
4.37%
IHE
USA
90.92%
Other
9.08%

Sectors

FTXH
Health Care
98.8%
Other
1.2%
IHE
Health Care
96.19%
Other
3.81%
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Diversification

FTXH

Total weight of top 15 holdings out of 15

71.63%
IHE

Total weight of top 15 holdings out of 15

84.8%

Top 15 holdings

Data as of January 31, 2026
FTXH
MERCK & CO INC
7.83%
JOHNSON&JOHNSON
7.66%
BRISTOL-MYERS SQUIBB
6.97%
PFIZER
6.38%
ABBVIE
6.33%
CARDINAL HEALTH
4.31%
LILLY
4.23%
BIOGEN INC
3.99%
REGENERON PHARMACEUTICALS
3.81%
GILEAD SCIENCES
3.75%
VIATRIS INC
3.71%
VERTEX PHARMACEUTICALS
3.59%
AMGEN-T
3.55%
UTD THERAPEUT
3.14%
ZOETIS INC
2.38%
IHE
JOHNSON&JOHNSON
23.72%
LILLY
22.21%
MERCK & CO INC
4.78%
BRISTOL-MYERS SQUIBB
4.57%
ZOETIS INC
4.44%
PFIZER
4.36%
ROYALTY PHARMA
4.08%
VIATRIS INC
4.00%
ELANCO ANIMAL HEALTH INC
3.20%
JAZZ PHARMACEUTICALS
2.65%
AXSOME THERA CMN STK
2.09%
CRINETICS PHARMACEUTICALS
1.41%
US45579U1097
1.15%
CORCEPT THERAPEUTICS
1.11%
LIGAND PHARMACEUTICALS
1.02%
Frequently asked questions about FTXH and IHE

How have the FTXH and IHE ETFs performed in 2026?

As of March 12, 2026, FTXH is up 2.6% year-to-date (YTD), while IHE has returned 2.22%. That puts FTXH better performer ahead so far this year.

Which ETF is attracting more investor money: FTXH or IHE?

Year-to-date, the FTXH ETF saw +$7M in flows, compared to +$129M for IHE.

Which ETF is more volatile: FTXH or IHE?

Over the past year, FTXH had a volatility of 20.64%, while IHE experienced 20.48%.

Which ETF is bigger: FTXH or IHE?

As of March 12, 2026, FTXH holds $28.72 M in assets under management (AUM), while IHE manages $996.54 M.

What sectors do the FTXH and IHE ETFs invest in?

FTXH leans toward sectors like Health Care. Meanwhile, IHE focuses on Health Care.

What are the top holdings of the FTXH ETF and IHE ETF?

FTXH top holdings include MERCK & CO INC, JOHNSON&JOHNSON and BRISTOL-MYERS SQUIBB. IHE holds in its top three: JOHNSON&JOHNSON, LILLY and MERCK & CO INC.

Which ETF is more diversified: FTXH or IHE?

FTXH holds 50 securities with 71.63% of its assets in the top 15. IHE has 56 securities and a top 15 weight of 84.8%.

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