FTXHvsIHEETF Comparison
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First Trust Nasdaq Pharmaceuticals ETF (FTXH) and iShares U.S. Pharmaceuticals ETF (IHE) belong to the same industry segment: US Health Care. Both ETFs have the same top 3 sector exposures: and Health Care. FTXH is more expensive with a Total Expense Ratio (TER) of 0.6%, versus 0.38% for IHE. FTXH is up 9.46% year-to-date (YTD) with +$10M in YTD flows. IHE performs better with 12.18% YTD performance, and +$30M in YTD flows. Run a side-by-side ETF comparison of FTXH and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FTXH vs IHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FTXH IHE | +4.89%+7.66% | +6.69%+9.75% | +9.46%+12.18% | +38.27%+42.29% | +43.75%+69.67% | +46.87%+64.77% |
| Flows | FTXH IHE | -$2M+$38M | +$3M-$98M | +$10M+$30M | +$7M+$164M | -$3M+$261M | +$5M+$294M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FTXH IHE | +17.83%+19.63% | +17.06%+17.30% | +16.29%+16.52% | +15.91%+16.23% |
| Max drawdown | FTXH IHE | -4.47%-4.47% | -7.50%-8.48% | -19.32%-16.04% | -19.32%-16.12% |
| Max drawdown duration | FTXH IHE | 32d15d | 99d81d | 393d210d | 393d669d |
Trading data
FTXH | IHE | |
Last sale 6/12/2026 at 1:30 PM | $36.01 | $94.75 |
| Previous close 06/12/2026 | $36.09 | $95.07 |
| Consolidated volume 06/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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FTXH | IHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
FTXH | IHE | |
|---|---|---|
| Last price | $36.01 | $94.75 |
| 1D performance | -0.21% | -0.34% |
| AuM | $34.18 M | $981.06 M |
| E/R | 0.6% | 0.38% |
Characteristics
FTXH | IHE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | NASDAQ US Smart Pharmaceuticals Index | Dow Jones U.S. Select Pharmaceuticals Index |
| N° of holdings | 47 | 45 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 20, 2016 | May 1, 2006 |
| ESG | No | No |
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Exposure
Countries
FTXH
USA
93.7%
Other
6.3%
IHE
USA
90.2%
Other
9.8%
Sectors
FTXH
Health Care
97.61%
Other
2.39%
IHE
Health Care
95.09%
Other
4.91%
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Diversification
FTXH
Total weight of top 15 holdings out of 15
69.57%
IHE
Total weight of top 15 holdings out of 15
83.6%
Top 15 holdings
Data as of April 30, 2026
FTXH
BRISTOL-MYERS SQUIBB
7.25%
JOHNSON&JOHNSON
7.12%
MERCK & CO INC
6.90%
ABBVIE
6.61%
LILLY
6.45%
VIATRIS INC
3.85%
PFIZER
3.72%
BIOGEN INC
3.71%
REGENERON PHARMACEUTICALS
3.63%
CARDINAL HEALTH
3.48%
ZOETIS INC
3.45%
AMGEN-T
3.40%
GILEAD SCIENCES
3.37%
VERTEX PHARMACEUTICALS
3.36%
UTD THERAPEUT
3.26%
IHE
JOHNSON&JOHNSON
21.40%
LILLY
21.14%
ROYALTY PHARMA
4.85%
VIATRIS INC
4.75%
BRISTOL-MYERS SQUIBB
4.57%
PFIZER
4.42%
ZOETIS INC
4.34%
MERCK & CO INC
4.25%
JAZZ PHARMACEUTICALS
3.40%
ELANCO ANIMAL HEALTH INC
3.07%
AXSOME THERA CMN STK
2.43%
US45579U1097
1.27%
TERNS PHARMACEUTICALS
1.26%
LIGAND PHARMACEUTICALS
1.25%
CORCEPT THERAPEUTICS
1.20%
Frequently asked questions about FTXH and IHE
How have the FTXH and IHE ETFs performed in 2026?
As of June 12, 2026, FTXH is up 9.46% year-to-date (YTD), while IHE has returned 12.18%. That puts IHE better performer ahead so far this year.
Which ETF is attracting more investor money: FTXH or IHE?
Year-to-date, the FTXH ETF saw +$10M in flows, compared to +$30M for IHE.
Which ETF is more volatile: FTXH or IHE?
Over the past year, FTXH had a volatility of 17.06%, while IHE experienced 17.3%.
Which ETF is bigger: FTXH or IHE?
As of June 12, 2026, FTXH holds $34.18 M in assets under management (AUM), while IHE manages $981.06 M.
What sectors do the FTXH and IHE ETFs invest in?
FTXH leans toward sectors like Health Care. Meanwhile, IHE focuses on Health Care.
What are the top holdings of the FTXH ETF and IHE ETF?
FTXH top holdings include BRISTOL-MYERS SQUIBB, JOHNSON&JOHNSON and MERCK & CO INC. IHE holds in its top three: JOHNSON&JOHNSON, LILLY and ROYALTY PHARMA.
Which ETF is more diversified: FTXH or IHE?
FTXH holds 47 securities with 69.57% of its assets in the top 15. IHE has 57 securities and a top 15 weight of 83.6%.
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