FTXHvsIHEETF Comparison
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First Trust Nasdaq Pharmaceuticals ETF (FTXH) and iShares U.S. Pharmaceuticals ETF (IHE) belong to the same industry segment: US Health Care. FTXH's top 1 sector exposures are Healthcare. In contrast, IHE's top sector exposures are Healthcare and Non-Corporate. FTXH is more expensive with a Total Expense Ratio (TER) of 0.6%, versus 0.37% for IHE. FTXH is up 23.32% year-to-date (YTD) with +$978M in YTD flows. IHE performs worse with 20.01% YTD performance, and +$599M in YTD flows. Run a side-by-side ETF comparison of FTXH and IHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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FTXH vs IHE performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/10/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | FTXH IHE | +0.75%-1.66% | +14.81%+6.69% | +23.32%+20.01% | +46.70%+43.32% | +58.20%+67.13% | +66.91%+75.14% |
| Flows | FTXH IHE | +$41M+$22M | +$968M+$602M | +$978M+$599M | +$981M+$756M | +$973M+$848M | +$977M+$853M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | FTXH IHE | +20.07%+19.74% | +17.74%+18.28% | +16.99%+17.01% | +16.34%+16.58% |
| Max drawdown | FTXH IHE | -5.34%-6.47% | -7.50%-8.48% | -19.32%-16.04% | -19.32%-16.12% |
| Max drawdown duration | FTXH IHE | 16d23d | 99d81d | 393d210d | 393d669d |
Trading data
FTXH | IHE | |
Last sale 9/11/2026 at 7:59 PM | $40.45 | $101.91 |
| Previous close 09/11/2026 | $40.52 | $101.07 |
| Consolidated volume 09/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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FTXH | IHE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/11/2026 at 7:59 PM
Live
Closed
FTXH | IHE | |
|---|---|---|
| Last price | $40.45 | $101.91 |
| 1D performance | -0.17% | +0.83% |
| AuM | $1.04 B | $1.62 B |
| E/R | 0.6% | 0.37% |
Characteristics
FTXH | IHE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | NASDAQ US Smart Pharmaceuticals Index | Dow Jones U.S. Select Pharmaceuticals Index |
| N° of holdings | 49 | 57 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 20, 2016 | May 1, 2006 |
| ESG | No | No |
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Exposure
Countries
FTXH
USA
95.79%
Other
4.21%
IHE
USA
95.81%
Other
4.19%
Sectors
FTXH
Healthcare
99.86%
Other
0.14%
IHE
Healthcare
99.62%
Other
0.38%
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Diversification
FTXH
Total weight of top 15 holdings out of 15
66.98%
IHE
Total weight of top 15 holdings out of 15
84.32%
Top 15 holdings
Data as of July 31, 2026
FTXH
Merck & Co., Inc.
7.58%
Eli Lilly & Co.
7.43%
AbbVie, Inc.
7.11%
Johnson & Johnson
6.78%
Bristol Myers Squibb Co.
6.61%
Amgen, Inc.
3.53%
Biogen, Inc.
3.52%
Vertex Pharmaceuticals, Inc.
3.43%
Viatris, Inc.
3.40%
Regeneron Pharmaceuticals, Inc.
3.34%
Pfizer Inc.
3.17%
Cardinal Health, Inc.
3.14%
Gilead Sciences, Inc.
3.03%
Incyte Corp.
2.48%
United Therapeutics Corp.
2.43%
IHE
Johnson & Johnson
21.85%
Eli Lilly & Co.
20.71%
Bristol Myers Squibb Co.
4.75%
Viatris, Inc.
4.56%
Merck & Co., Inc.
4.44%
Royalty Pharma Plc
4.41%
Pfizer Inc.
3.96%
Zoetis, Inc.
3.81%
Jazz Pharmaceuticals Plc
3.58%
Elanco Animal Health, Inc.
2.92%
Corcept Therapeutics, Inc.
2.49%
Axsome Therapeutics, Inc.
2.24%
Crinetics Pharmaceuticals, Inc.
1.95%
Liquidia Corp.
1.35%
Ligand Pharmaceuticals, Inc.
1.31%
Frequently asked questions about FTXH and IHE
How have the FTXH and IHE ETFs performed in 2026?
As of September 10, 2026, FTXH is up 23.32% year-to-date (YTD), while IHE has returned 20.01%. That puts FTXH better performer ahead so far this year.
Which ETF is attracting more investor money: FTXH or IHE?
Year-to-date, the FTXH ETF saw +$978M in flows, compared to +$599M for IHE.
Which ETF is more volatile: FTXH or IHE?
Over the past year, FTXH had a volatility of 17.74%, while IHE experienced 18.28%.
Which ETF is bigger: FTXH or IHE?
As of September 10, 2026, FTXH holds $1.04 B in assets under management (AUM), while IHE manages $1.62 B.
What sectors do the FTXH and IHE ETFs invest in?
FTXH leans toward sectors like Healthcare. Meanwhile, IHE focuses on Healthcare.
What are the top holdings of the FTXH ETF and IHE ETF?
FTXH top holdings include Merck & Co., Inc., Eli Lilly & Co. and AbbVie, Inc.. IHE holds in its top three: Johnson & Johnson, Eli Lilly & Co. and Bristol Myers Squibb Co..
Which ETF is more diversified: FTXH or IHE?
FTXH holds 49 securities with 66.98% of its assets in the top 15. IHE has 57 securities and a top 15 weight of 84.32%.
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