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CANCvsOZEMETF Comparison

ETF 1
CANC

Tema Oncology ETF

This fund is part of
Tomorrow's Treatments
-2.17%
Full CANC fund page
VS
ETF 2
OZEM

Roundhill GLP-1 & Weight Loss ETF

This fund is part of
Tomorrow's Treatments
-2.17%
Full OZEM fund page

Tema Oncology ETF (CANC) and Roundhill GLP-1 & Weight Loss ETF (OZEM) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.59% for OZEM. CANC is up 4.1% year-to-date (YTD) with +$41M in YTD flows. OZEM performs worse with -7.16% YTD performance, and +$16M in YTD flows. Run a side-by-side ETF comparison of CANC and OZEM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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CANC vs OZEM performance and flow charts

Performance

-10.0-5.00.0%Feb 12Feb 20Feb 27Mar 6

Cumulative Flows

0 M2 M4 M6 M8 M10 M12 MFeb 12Feb 20Feb 27Mar 6

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/12/2026
1M3MYTD1Y3Y5Y
Perf.
CANC
OZEM
-0.94%-10.89%
+4.18%-7.23%
+4.10%-7.16%
+43.76%+31.31%
n/an/a
n/an/a
Flows
CANC
OZEM
+$12M+$3M
+$49M+$16M
+$41M+$16M
+$63M+$10M
--
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
CANC
OZEM
+23.29%+22.47%
+25.13%+25.49%
n/an/a
n/an/a
Max drawdown
CANC
OZEM
-4.68%-14.23%
-17.26%-15.51%
n/an/a
n/an/a
Max drawdown duration
CANC
OZEM
16d45d
80d42d
n/an/a
n/an/a
Trading data

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CANC
OZEM
Last sale
3/13/2026 at 1:30 PM
$35.99
$31.33
Previous close
03/12/2026
$36.33
$31.59
Consolidated volume
03/12/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
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Main metrics
Last update 3/13/2026 at 1:30 PM
Live
Closed
CANC
OZEM
Last price
$35.99
$31.33
1D performance
-0.95%
-0.80%
AuM$161.18 M$55.72 M
E/R0.99%0.59%
Characteristics
CANC
OZEM
Management strategyActiveActive
ProviderTemaRoundhill Investments
Benchmark--
N° of holdings4620
Asset class--
Trailing 12m distribution yield
Join
Join
Inception dateAugust 15, 2023May 21, 2024
ESGNoNo
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Exposure

Countries

CANC
USA
88.08%
Other
11.92%
OZEM
USA
63.33%
Cayman Islands
9%
Other
27.67%

Sectors

CANC
Health Care
80.79%
Other
19.21%
OZEM
Health Care
65.61%
Other
34.39%
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Diversification

CANC

Total weight of top 15 holdings out of 15

56.2%
OZEM

Total weight of top 15 holdings out of 15

84.13%

Top 15 holdings

Data as of January 31, 2026
CANC
REVOLUTION MEDICINES INC
6.31%
BRIDGEBIO PHARMA
4.61%
NOVARTIS
4.56%
ASTRAZENECA
4.33%
US7711951043
4.14%
LILLY
3.94%
BRISTOL-MYERS SQUIBB
3.89%
US3723032062
3.68%
MERCK & CO INC
3.49%
COGENT BIOSCIENCES
3.42%
NUVALENT
3.25%
IMMUNOME
2.96%
CELCUITY INC
2.67%
AMGEN-T
2.51%
JOHNSON&JOHNSON
2.44%
OZEM
US6701002056
22.10%
LILLY
14.43%
US86366E1064
4.93%
ROCHE
4.21%
PFIZER
3.92%
CHUGAI PHARMACEUTICAL
3.92%
ZEALAND PHARMA
3.84%
HANMI PHARM
3.77%
PHARMA INC
3.72%
VIKING THERPTC/D
3.60%
AMGEN-T
3.54%
INNOVENT BIOLOGICS INC
3.29%
SHANGHAI FOSUN PHARMACEUTICAL (GRP)I
3.20%
US0463531089
3.06%
REGENERON PHARMACEUTICALS
2.60%
Frequently asked questions about CANC and OZEM

How have the CANC and OZEM ETFs performed in 2026?

As of March 12, 2026, CANC is up 4.1% year-to-date (YTD), while OZEM has lost -7.16%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: CANC or OZEM?

Year-to-date, the CANC ETF saw +$41M in flows, compared to +$16M for OZEM.

Which ETF is more volatile: CANC or OZEM?

Over the past year, CANC had a volatility of 25.13%, while OZEM experienced 25.49%.

Which ETF is bigger: CANC or OZEM?

As of March 12, 2026, CANC holds $161.18 M in assets under management (AUM), while OZEM manages $55.72 M.

What sectors do the CANC and OZEM ETFs invest in?

CANC leans toward sectors like Health Care. Meanwhile, OZEM focuses on Health Care.

What are the top holdings of the CANC ETF and OZEM ETF?

CANC top holdings include REVOLUTION MEDICINES INC, BRIDGEBIO PHARMA and NOVARTIS. OZEM holds in its top three: US6701002056, LILLY and US86366E1064.

Which ETF is more diversified: CANC or OZEM?

CANC holds 56 securities with 56.2% of its assets in the top 15. OZEM has 24 securities and a top 15 weight of 84.13%.

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