CANCvsHRTSETF Comparison
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Tema Oncology ETF (CANC) and Tema GLP-1, Obesity & Cardiometabolic ETF (HRTS) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. Both CANC and HRTS have the same Total Expense Ratio (TER) of 0.99%. CANC is up 5.65% year-to-date (YTD) with +$50M in YTD flows. HRTS performs worse with -7.09% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of CANC and HRTS below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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CANC vs HRTS performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/29/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | CANC HRTS | +4.36%+0.22% | +1.62%-7.83% | +5.65%-7.09% | +48.55%+15.13% | n/an/a | n/an/a |
| Flows | CANC HRTS | +$5M-$1M | +$26M-$4M | +$50M-$2M | +$70M-$12M | -- | -- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | CANC HRTS | +23.58%+16.39% | +23.48%+16.33% | n/an/a | n/an/a |
| Max drawdown | CANC HRTS | -7.99%-9.68% | -10.53%-10.68% | n/an/a | n/an/a |
| Max drawdown duration | CANC HRTS | 43d59d | 32d112d | n/an/a | n/an/a |
Trading data
CANC | HRTS | |
Last sale 4/30/2026 at 1:30 PM | $37.61 | $33.65 |
| Previous close 04/29/2026 | $36.58 | $32.83 |
| Consolidated volume 04/29/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 4/30/2026 at 1:30 PM
Live
Closed
CANC | HRTS | |
|---|---|---|
| Last price | $37.61 | $33.65 |
| 1D performance | +2.83% | +2.51% |
| AuM | $171.62 M | $48.91 M |
| E/R | 0.99% | 0.99% |
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Exposure
Countries
CANC
USA
85.51%
Other
14.49%
HRTS
USA
82.47%
Other
17.53%
Sectors
CANC
Health Care
78.17%
Other
21.83%
HRTS
Health Care
87.86%
Other
12.14%
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Diversification
CANC
Total weight of top 15 holdings out of 15
56.1%
HRTS
Total weight of top 15 holdings out of 15
61.52%
Top 15 holdings
Data as of March 31, 2026
CANC
REVOLUTION MEDICINES INC
4.95%
ASTRAZENECA
4.60%
NOVARTIS
4.45%
US7711951043
4.26%
LILLY
4.20%
BRIDGEBIO PHARMA
3.94%
COGENT BIOSCIENCES
3.88%
BRISTOL-MYERS SQUIBB
3.74%
MERCK & CO INC
3.62%
IMMUNOME
3.30%
JOHNSON&JOHNSON
3.23%
NUVALENT
3.20%
CELCUITY INC
3.07%
US3723032062
2.95%
ABBVIE
2.71%
HRTS
LILLY
9.70%
JOHNSON&JOHNSON
4.97%
US7711951043
4.94%
ASTRAZENECA
4.91%
MERCK & CO INC
4.46%
THERMO FISHER SCIENTIFIC
4.06%
UNITEDHEALTH GRP
3.79%
GILEAD SCIENCES
3.66%
NOVARTIS
3.52%
VERTEX PHARMACEUTICALS
3.30%
ABBOTT LABS
3.26%
ABBVIE
3.00%
BRIDGEBIO PHARMA
2.85%
DANAHER
2.81%
BRISTOL-MYERS SQUIBB
2.29%
Frequently asked questions about CANC and HRTS
How have the CANC and HRTS ETFs performed in 2026?
As of April 29, 2026, CANC is up 5.65% year-to-date (YTD), while HRTS has lost -7.09%. That puts CANC better performer ahead so far this year.
Which ETF is attracting more investor money: CANC or HRTS?
Year-to-date, the CANC ETF saw +$50M in flows, compared to -$2M for HRTS.
Which ETF is more volatile: CANC or HRTS?
Over the past year, CANC had a volatility of 23.48%, while HRTS experienced 16.33%.
Which ETF is bigger: CANC or HRTS?
As of April 29, 2026, CANC holds $171.62 M in assets under management (AUM), while HRTS manages $48.91 M.
What sectors do the CANC and HRTS ETFs invest in?
CANC leans toward sectors like Health Care. Meanwhile, HRTS focuses on Health Care.
What are the top holdings of the CANC ETF and HRTS ETF?
CANC top holdings include REVOLUTION MEDICINES INC, ASTRAZENECA and NOVARTIS. HRTS holds in its top three: LILLY, JOHNSON&JOHNSON and US7711951043.
Which ETF is more diversified: CANC or HRTS?
CANC holds 54 securities with 56.1% of its assets in the top 15. HRTS has 44 securities and a top 15 weight of 61.52%.
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Latest news about CANC & HRTS
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