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CANCvsBBCETF Comparison
Tema Oncology ETF (CANC) and Virtus LifeSci Biotech Clinical Trials ETF (BBC) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. CANC is more expensive with a Total Expense Ratio (TER) of 0.99%, versus 0.79% for BBC. CANC is up 4.1% year-to-date (YTD) with +$41M in YTD flows. BBC performs better with 11.12% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of CANC and BBC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
CANC vs BBC performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | CANC BBC | -0.94%+5.80% | +4.18%+9.44% | +4.10%+11.12% | +43.76%+121.56% | n/a+90.43% | n/a-21.96% |
| Flows | CANC BBC | +$12M+$2M | +$49M+$6M | +$41M+$2M | +$63M+$17M | -+$11M | --$2M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | CANC BBC | +23.29%+34.38% | +25.13%+39.86% | n/a+36.22% | n/a+39.36% |
| Max drawdown | CANC BBC | -4.68%-11.00% | -17.26%-30.12% | n/a-54.25% | n/a-74.98% |
| Max drawdown duration | CANC BBC | 16d48d | 80d85d | n/a340d | n/a1822d |
CANC | BBC | |
Last sale 3/13/2026 at 1:30 PM | $35.99 | $40.65 |
| Previous close 03/12/2026 | $36.33 | $41.40 |
| Consolidated volume 03/12/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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CANC | BBC | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
CANC | BBC | |
|---|---|---|
| Last price | $35.99 | $40.65 |
| 1D performance | -0.95% | -1.81% |
| AuM | $161.18 M | $38.68 M |
| E/R | 0.99% | 0.79% |
CANC | BBC | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Tema | VIRTUS Investment Partners |
| Benchmark | - | LifeSci Biotechnology Clinical Trials Index |
| N° of holdings | 46 | 81 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | August 15, 2023 | December 16, 2014 |
| ESG | No | No |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the CANC and BBC ETFs performed in 2026?
As of March 12, 2026, CANC is up 4.1% year-to-date (YTD), while BBC has returned 11.12%. That puts BBC better performer ahead so far this year.
Which ETF is attracting more investor money: CANC or BBC?
Year-to-date, the CANC ETF saw +$41M in flows, compared to +$2M for BBC.
Which ETF is more volatile: CANC or BBC?
Over the past year, CANC had a volatility of 25.13%, while BBC experienced 39.86%.
Which ETF is bigger: CANC or BBC?
As of March 12, 2026, CANC holds $161.18 M in assets under management (AUM), while BBC manages $38.68 M.
What sectors do the CANC and BBC ETFs invest in?
CANC leans toward sectors like Health Care. Meanwhile, BBC focuses on Health Care.
What are the top holdings of the CANC ETF and BBC ETF?
CANC top holdings include REVOLUTION MEDICINES INC, BRIDGEBIO PHARMA and NOVARTIS. BBC holds in its top three: CORVUS PHARMACEUTICALS INC, ERASCA and US0223071020.
Which ETF is more diversified: CANC or BBC?
CANC holds 56 securities with 56.2% of its assets in the top 15. BBC has 122 securities and a top 15 weight of 18.83%.
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