BBPvsOZEMETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) and Roundhill GLP-1 & Weight Loss ETF (OZEM) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.59% for OZEM. BBP is up 9.25% year-to-date (YTD) with +$30M in YTD flows. OZEM performs worse with -10.57% YTD performance, and +$12M in YTD flows. Run a side-by-side ETF comparison of BBP and OZEM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs OZEM performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP OZEM | -1.38%-3.86% | +7.00%-3.67% | +9.25%-10.57% | +43.65%+11.27% | +60.05%n/a | +58.90%n/a |
| Flows | BBP OZEM | +$4M+$2M | +$26M-$4M | +$30M+$12M | +$42M+$9M | +$45M- | +$38M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP OZEM | +28.75%+20.46% | +24.06%+22.78% | +24.00%n/a | +26.36%n/a |
| Max drawdown | BBP OZEM | -7.49%-8.22% | -9.59%-19.51% | -25.54%n/a | -37.87%n/a |
| Max drawdown duration | BBP OZEM | 37d54d | 48d137d | 292dn/a | 760dn/a |
Trading data
BBP | OZEM | |
Last sale 6/12/2026 at 1:30 PM | $87.17 | $30.56 |
| Previous close 06/11/2026 | $86.80 | $30.85 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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OZEM
is actively managed and doesn’t replicate an indexBBP | OZEM | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
BBP | OZEM | |
|---|---|---|
| Last price | $87.17 | $30.56 |
| 1D performance | +0.42% | -0.95% |
| AuM | $78.43 M | $49.70 M |
| E/R | 0.79% | 0.59% |
Characteristics
BBP | OZEM | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | VIRTUS Investment Partners | Roundhill Investments |
| Benchmark | LifeSci Biotechnology Products Index | - |
| N° of holdings | 55 | 19 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | May 21, 2024 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
84.13%
Other
15.87%
OZEM
USA
57.73%
Cayman Islands
12.38%
Other
29.89%
Sectors
BBP
Health Care
85.97%
Other
14.03%
OZEM
Health Care
72.31%
Other
27.69%
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Diversification
BBP
Total weight of top 15 holdings out of 15
45.32%
OZEM
Total weight of top 15 holdings out of 15
84.11%
Top 15 holdings
Data as of April 30, 2026
BBP
ARROWHEAD PHARMACEUTICALS INC
3.17%
GB00BRXB0C07
3.17%
BIOGEN INC
3.14%
HALOZYME THERAPEUTICS
3.13%
AURINIA PHARMACEUTICALS INC
3.12%
SYNDAX PHARMACEUTICALS INC
3.12%
BIOMARIN PHARMACEUTICAL
3.05%
INCYTE
3.03%
REGENERON PHARMACEUTICALS
3.03%
BRIDGEBIO PHARMA
3.00%
SAREPTA THERAPEUTICS INC DE
2.95%
ARDELYX
2.92%
VERTEX PHARMACEUTICALS
2.85%
US07725L1026
2.83%
THERAVANCE BIOPHARMA
2.80%
OZEM
LILLY
15.27%
US6701002056
14.79%
PFIZER
7.24%
VIKING THERPTC/D
5.38%
PHARMA INC
5.06%
INNOVENT BIOLOGICS INC
5.05%
CH1499059983
4.12%
AMGEN-T
3.83%
ZEALAND PHARMA
3.78%
HANMI PHARM
3.67%
ASTRAZENECA
3.60%
SHANGHAI FOSUN PHARMACEUTICAL (GRP)I
3.25%
REGENERON PHARMACEUTICALS
3.22%
CHUGAI PHARMACEUTICAL
3.00%
CSPC PHARMACEUTICAL GROUP LTD
2.85%
Frequently asked questions about BBP and OZEM
How have the BBP and OZEM ETFs performed in 2026?
As of June 12, 2026, BBP is up 9.25% year-to-date (YTD), while OZEM has lost -10.57%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or OZEM?
Year-to-date, the BBP ETF saw +$30M in flows, compared to +$12M for OZEM.
Which ETF is more volatile: BBP or OZEM?
Over the past year, BBP had a volatility of 24.06%, while OZEM experienced 22.78%.
Which ETF is bigger: BBP or OZEM?
As of June 12, 2026, BBP holds $78.43 M in assets under management (AUM), while OZEM manages $49.70 M.
What sectors do the BBP and OZEM ETFs invest in?
BBP leans toward sectors like Health Care. Meanwhile, OZEM focuses on Health Care.
What are the top holdings of the BBP ETF and OZEM ETF?
BBP top holdings include ARROWHEAD PHARMACEUTICALS INC, GB00BRXB0C07 and BIOGEN INC. OZEM holds in its top three: LILLY, US6701002056 and PFIZER.
Which ETF is more diversified: BBP or OZEM?
BBP holds 59 securities with 45.32% of its assets in the top 15. OZEM has 25 securities and a top 15 weight of 84.11%.
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