BBPvsOZEMETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) and Roundhill GLP-1 & Weight Loss ETF (OZEM) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Healthcare. BBP is less expensive with a Total Expense Ratio (TER) of 0.34%, versus 0.59% for OZEM. BBP is up 21.54% year-to-date (YTD) with +$40M in YTD flows. OZEM performs worse with -5.02% YTD performance, and +$22M in YTD flows. Run a side-by-side ETF comparison of BBP and OZEM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs OZEM performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP OZEM | +0.94%-0.73% | +15.67%+5.00% | +21.54%-5.02% | +56.59%+23.49% | +81.31%n/a | +94.15%n/a |
| Flows | BBP OZEM | +$10M+$10M | +$28M+$9M | +$40M+$22M | +$52M+$22M | +$55M- | +$48M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP OZEM | +26.32%+21.47% | +24.02%+22.73% | +24.33%n/a | +26.47%n/a |
| Max drawdown | BBP OZEM | -7.49%-6.63% | -9.59%-19.51% | -25.54%n/a | -37.61%n/a |
| Max drawdown duration | BBP OZEM | 44d51d | 48d182d | 292dn/a | 586dn/a |
Trading data
BBP | OZEM | |
Last sale 7/28/2026 at 1:30 PM | $97.69 | $32.81 |
| Previous close 07/27/2026 | $97.26 | $32.55 |
| Consolidated volume 07/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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OZEM
is actively managed and doesn’t replicate an indexBBP | OZEM | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/28/2026 at 1:30 PM
Live
Closed
BBP | OZEM | |
|---|---|---|
| Last price | $97.69 | $32.81 |
| 1D performance | +0.45% | +0.80% |
| AuM | $96.94 M | $62.51 M |
| E/R | 0.34% | 0.59% |
Characteristics
BBP | OZEM | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | VIRTUS Investment Partners | Roundhill Investments |
| Benchmark | LifeSci Biotechnology Products Index | - |
| N° of holdings | 66 | 24 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | May 21, 2024 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
89.11%
Other
10.89%
OZEM
USA
44.42%
Denmark
19.13%
China
16.37%
Other
20.08%
Sectors
BBP
Healthcare
89.47%
Other
10.53%
OZEM
Healthcare
99.56%
Other
0.44%
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Diversification
BBP
Total weight of top 15 holdings out of 15
87.15%
OZEM
Total weight of top 15 holdings out of 15
82.24%
Top 15 holdings
Data as of June 30, 2026
BBP
Verastem, Inc.
44.58%
Legend Biotech Corp.
41.98%
Agios Pharmaceuticals, Inc.
0.05%
BioCryst Pharmaceuticals, Inc.
0.05%
BioMarin Pharmaceutical, Inc.
0.05%
Rigel Pharmaceuticals, Inc.
0.05%
Crinetics Pharmaceuticals, Inc.
0.05%
Madrigal Pharmaceuticals, Inc.
0.05%
BioNTech SE
0.05%
Iovance Biotherapeutics, Inc.
0.05%
Rhythm Pharmaceuticals, Inc.
0.05%
Alnylam Pharmaceuticals, Inc.
0.05%
Incyte Corp.
0.05%
Sarepta Therapeutics, Inc.
0.05%
Omeros Corp.
0.05%
OZEM
Novo Nordisk A/S
13.29%
Eli Lilly & Co.
13.07%
Pfizer Inc.
6.58%
Kailera Therapeutics, Inc.
6.00%
Viking Therapeutics, Inc.
5.84%
CSPC Pharmaceutical Group Ltd.
5.22%
Chugai Pharmaceutical Co., Ltd.
4.53%
Ascletis Pharma, Inc.
3.95%
Zealand Pharma A/S
3.93%
Amgen, Inc.
3.89%
AstraZeneca PLC
3.89%
Hanmi Pharmaceutical Co., Ltd.
3.33%
Roche Holding AG
3.12%
Structure Therapeutics, Inc.
2.89%
MBX Biosciences, Inc.
2.71%
Frequently asked questions about BBP and OZEM
How have the BBP and OZEM ETFs performed in 2026?
As of July 27, 2026, BBP is up 21.54% year-to-date (YTD), while OZEM has lost -5.02%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or OZEM?
Year-to-date, the BBP ETF saw +$40M in flows, compared to +$22M for OZEM.
Which ETF is more volatile: BBP or OZEM?
Over the past year, BBP had a volatility of 24.02%, while OZEM experienced 22.73%.
Which ETF is bigger: BBP or OZEM?
As of July 27, 2026, BBP holds $96.94 M in assets under management (AUM), while OZEM manages $62.51 M.
What sectors do the BBP and OZEM ETFs invest in?
BBP leans toward sectors like Healthcare. Meanwhile, OZEM focuses on Healthcare.
What are the top holdings of the BBP ETF and OZEM ETF?
BBP top holdings include Verastem, Inc., Legend Biotech Corp. and Agios Pharmaceuticals, Inc.. OZEM holds in its top three: Novo Nordisk A/S, Eli Lilly & Co. and Pfizer Inc..
Which ETF is more diversified: BBP or OZEM?
BBP holds 66 securities with 87.15% of its assets in the top 15. OZEM has 24 securities and a top 15 weight of 82.24%.
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Latest news about BBP & OZEM
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