BBPvsHRTSETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) and Tema GLP-1, Obesity & Cardiometabolic ETF (HRTS) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 3 sector exposures: and Health Care. BBP is less expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.99% for HRTS. BBP is up 9.25% year-to-date (YTD) with +$30M in YTD flows. HRTS performs worse with -2.91% YTD performance, and -$1M in YTD flows. Run a side-by-side ETF comparison of BBP and HRTS below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs HRTS performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP HRTS | -1.38%+1.69% | +7.00%+1.34% | +9.25%-2.91% | +43.65%+19.31% | +60.05%n/a | +58.90%n/a |
| Flows | BBP HRTS | +$4M+$344K | +$26M-$339K | +$30M-$1M | +$42M-$10M | +$45M- | +$38M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP HRTS | +28.75%+17.41% | +24.06%+15.73% | +24.00%n/a | +26.36%n/a |
| Max drawdown | BBP HRTS | -7.49%-5.26% | -9.59%-10.68% | -25.54%n/a | -37.87%n/a |
| Max drawdown duration | BBP HRTS | 37d54d | 48d156d | 292dn/a | 760dn/a |
Trading data
BBP | HRTS | |
Last sale 6/12/2026 at 1:30 PM | $87.17 | $34.27 |
| Previous close 06/11/2026 | $86.80 | $34.44 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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HRTS
is actively managed and doesn’t replicate an indexBBP | HRTS | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
BBP | HRTS | |
|---|---|---|
| Last price | $87.17 | $34.27 |
| 1D performance | +0.42% | -0.47% |
| AuM | $78.43 M | $52.14 M |
| E/R | 0.79% | 0.99% |
Characteristics
BBP | HRTS | |
|---|---|---|
| Management strategy | Passive | Active |
| Provider | VIRTUS Investment Partners | Tema |
| Benchmark | LifeSci Biotechnology Products Index | - |
| N° of holdings | 55 | 38 |
| Asset class | Equities | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | November 21, 2023 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
84.13%
Other
15.87%
HRTS
USA
81.88%
Other
18.12%
Sectors
BBP
Health Care
85.97%
Other
14.03%
HRTS
Health Care
86.6%
Other
13.4%
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Diversification
BBP
Total weight of top 15 holdings out of 15
45.32%
HRTS
Total weight of top 15 holdings out of 15
61.36%
Top 15 holdings
Data as of April 30, 2026
BBP
ARROWHEAD PHARMACEUTICALS INC
3.17%
GB00BRXB0C07
3.17%
BIOGEN INC
3.14%
HALOZYME THERAPEUTICS
3.13%
AURINIA PHARMACEUTICALS INC
3.12%
SYNDAX PHARMACEUTICALS INC
3.12%
BIOMARIN PHARMACEUTICAL
3.05%
INCYTE
3.03%
REGENERON PHARMACEUTICALS
3.03%
BRIDGEBIO PHARMA
3.00%
SAREPTA THERAPEUTICS INC DE
2.95%
ARDELYX
2.92%
VERTEX PHARMACEUTICALS
2.85%
US07725L1026
2.83%
THERAVANCE BIOPHARMA
2.80%
HRTS
LILLY
9.40%
UNITEDHEALTH GRP
5.08%
US7711951043
4.92%
ASTRAZENECA
4.23%
JOHNSON&JOHNSON
4.23%
MERCK & CO INC
4.12%
DK0062498333
3.96%
THERMO FISHER SCIENTIFIC
3.92%
GILEAD SCIENCES
3.39%
NOVARTIS
3.38%
VERTEX PHARMACEUTICALS
3.14%
BRIDGEBIO PHARMA
3.03%
ABBOTT LABS
2.93%
REVOLUTION MEDICINES INC
2.89%
ABBVIE
2.74%
Frequently asked questions about BBP and HRTS
How have the BBP and HRTS ETFs performed in 2026?
As of June 12, 2026, BBP is up 9.25% year-to-date (YTD), while HRTS has lost -2.91%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or HRTS?
Year-to-date, the BBP ETF saw +$30M in flows, compared to -$1M for HRTS.
Which ETF is more volatile: BBP or HRTS?
Over the past year, BBP had a volatility of 24.06%, while HRTS experienced 15.73%.
Which ETF is bigger: BBP or HRTS?
As of June 12, 2026, BBP holds $78.43 M in assets under management (AUM), while HRTS manages $52.14 M.
What sectors do the BBP and HRTS ETFs invest in?
BBP leans toward sectors like Health Care. Meanwhile, HRTS focuses on Health Care.
What are the top holdings of the BBP ETF and HRTS ETF?
BBP top holdings include ARROWHEAD PHARMACEUTICALS INC, GB00BRXB0C07 and BIOGEN INC. HRTS holds in its top three: LILLY, UNITEDHEALTH GRP and US7711951043.
Which ETF is more diversified: BBP or HRTS?
BBP holds 59 securities with 45.32% of its assets in the top 15. HRTS has 43 securities and a top 15 weight of 61.36%.
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Latest news about BBP & HRTS
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