BBPvsBBCETF Comparison
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Virtus LifeSci Biotech Products ETF (BBP) and Virtus LifeSci Biotech Clinical Trials ETF (BBC) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 1 sector exposures: Healthcare. BBP is less expensive with a Total Expense Ratio (TER) of 0.34%, versus 0.65% for BBC. BBP is up 28.37% year-to-date (YTD) with +$66M in YTD flows. BBC performs worse with 6.45% YTD performance, and +$5M in YTD flows. Run a side-by-side ETF comparison of BBP and BBC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBP vs BBC performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/26/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBP BBC | -2.65%-10.61% | +5.62%-16.99% | +28.37%+6.45% | +38.01%+31.73% | +119.28%+143.56% | +100.33%-4.51% |
| Flows | BBP BBC | -- | +$26M- | +$66M+$5M | +$78M+$12M | +$83M+$16M | +$76M+$8M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBP BBC | +28.32%+36.10% | +26.44%+36.84% | +24.98%+37.63% | +26.86%+39.97% |
| Max drawdown | BBP BBC | -8.70%-29.70% | -9.59%-29.70% | -25.54%-54.25% | -37.61%-70.04% |
| Max drawdown duration | BBP BBC | 68d68d | 48d68d | 292d340d | 586d1625d |
Trading data
BBP | BBC | |
Last sale 10/27/2026 at 1:30 PM | $104.89 | $42.87 |
| Previous close 10/26/2026 | $102.33 | $41.06 |
| Consolidated volume 10/26/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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BBP | BBC | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 10/27/2026 at 1:30 PM
Live
Closed
BBP | BBC | |
|---|---|---|
| Last price | $104.89 | $42.87 |
| 1D performance | +2.50% | +4.40% |
| AuM | $127.99 M | $39.12 M |
| E/R | 0.34% | 0.65% |
Characteristics
BBP | BBC | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | VIRTUS Investment Partners |
| Benchmark | LifeSci Biotechnology Products Index | LifeSci Biotechnology Clinical Trials Index |
| N° of holdings | 66 | 127 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
BBP
USA
85.98%
Other
14.02%
BBC
USA
87.24%
Other
12.76%
Sectors
BBP
Healthcare
98.44%
Other
1.56%
BBC
Healthcare
96.27%
Other
3.73%
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Diversification
BBP
Total weight of top 15 holdings out of 15
31.08%
BBC
Total weight of top 15 holdings out of 15
17.14%
Top 15 holdings
Data as of August 31, 2026
BBP
Moderna, Inc.
3.58%
Crinetics Pharmaceuticals, Inc.
2.94%
Omeros Corp.
2.49%
Iovance Biotherapeutics, Inc.
2.36%
Verastem, Inc.
2.15%
Precigen, Inc.
1.99%
Halozyme Therapeutics, Inc.
1.84%
Zai Lab Ltd.
1.82%
Kiniksa Pharmaceuticals International Plc
1.81%
Kura Oncology, Inc.
1.72%
BeOne Medicines Ltd.
1.70%
Rigel Pharmaceuticals, Inc.
1.69%
Nuvation Bio, Inc.
1.69%
ACADIA Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
BBC
Amylyx Pharmaceuticals, Inc.
1.50%
First Tracks Biotherapeutics, Inc.
1.48%
AbCellera Biologics, Inc.
1.38%
Xencor, Inc.
1.36%
Monopar Therapeutics, Inc.
1.12%
MBX Biosciences, Inc.
1.11%
uniQure NV
1.09%
Replimune Group, Inc.
1.06%
4D Molecular Therapeutics, Inc.
1.04%
SELLAS Life Sciences Group, Inc.
1.04%
Alto Neuroscience, Inc.
1.00%
LB Pharmaceuticals, Inc.
1.00%
Oric Pharmaceuticals, Inc.
0.99%
Zenas BioPharma, Inc.
0.98%
Cullinan Therapeutics, Inc.
0.98%
Frequently asked questions about BBP and BBC
How have the BBP and BBC ETFs performed in 2026?
As of October 26, 2026, BBP is up 28.37% year-to-date (YTD), while BBC has returned 6.45%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBP or BBC?
Year-to-date, the BBP ETF saw +$66M in flows, compared to +$5M for BBC.
Which ETF is more volatile: BBP or BBC?
Over the past year, BBP had a volatility of 26.44%, while BBC experienced 36.84%.
Which ETF is bigger: BBP or BBC?
As of October 26, 2026, BBP holds $127.99 M in assets under management (AUM), while BBC manages $39.12 M.
What sectors do the BBP and BBC ETFs invest in?
BBP leans toward sectors like Healthcare. Meanwhile, BBC focuses on Healthcare.
What are the top holdings of the BBP ETF and BBC ETF?
BBP top holdings include Moderna, Inc., Crinetics Pharmaceuticals, Inc. and Omeros Corp.. BBC holds in its top three: Amylyx Pharmaceuticals, Inc., First Tracks Biotherapeutics, Inc. and AbCellera Biologics, Inc..
Which ETF is more diversified: BBP or BBC?
BBP holds 66 securities with 31.08% of its assets in the top 15. BBC has 127 securities and a top 15 weight of 17.14%.
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Latest news about BBP & BBC
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