BBCvsPSCHETF Comparison
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Virtus LifeSci Biotech Clinical Trials ETF (BBC) belongs to the Tomorrow's Treatments segment. Invesco S&P SmallCap Health Care ETF (PSCH) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Healthcare. BBC is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.29% for PSCH. BBC is up 28.23% year-to-date (YTD) with +$5M in YTD flows. PSCH performs worse with 20.01% YTD performance, and -$10M in YTD flows. Run a side-by-side ETF comparison of BBC and PSCH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBC vs PSCH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBC PSCH | -5.49%+1.16% | +8.79%+17.86% | +28.23%+20.01% | +126.14%+35.45% | +122.92%+21.50% | +14.49%-15.34% |
| Flows | BBC PSCH | +$83K+$2M | +$5M+$9M | +$5M-$10M | +$11M-$12M | +$15M-$133M | +$6M-$230M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBC PSCH | +38.48%+17.28% | +35.85%+20.10% | +37.04%+21.87% | +39.65%+22.90% |
| Max drawdown | BBC PSCH | -11.52%-2.96% | -14.64%-15.36% | -54.25%-22.80% | -70.93%-46.32% |
| Max drawdown duration | BBC PSCH | 44d20d | 60d168d | 340d488d | 1754d1789d |
Trading data
BBC | PSCH | |
Last sale 7/27/2026 at 7:57 PM | $49.74 | $53.21 |
| Previous close 07/27/2026 | $49.67 | $52.91 |
| Consolidated volume 07/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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BBC | PSCH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/27/2026 at 7:57 PM
Live
Closed
BBC | PSCH | |
|---|---|---|
| Last price | $49.74 | $53.21 |
| 1D performance | +0.14% | +0.56% |
| AuM | $47.12 M | $162.43 M |
| E/R | 0.65% | 0.29% |
Characteristics
BBC | PSCH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | Invesco |
| Benchmark | LifeSci Biotechnology Clinical Trials Index | S&P SmallCap 600 Capped Health Care Index |
| N° of holdings | 125 | 75 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | April 7, 2010 |
| ESG | No | No |
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Exposure
Countries
BBC
USA
85.4%
Other
14.6%
PSCH
USA
95.33%
Other
4.67%
Sectors
BBC
Healthcare
95.19%
Other
4.81%
PSCH
Healthcare
100%
Other
0%
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Diversification
BBC
Total weight of top 15 holdings out of 15
14.01%
PSCH
Total weight of top 15 holdings out of 15
49.48%
Top 15 holdings
Data as of June 30, 2026
BBC
uniQure NV
1.18%
REGENXBIO, Inc.
1.01%
Apogee Therapeutics, Inc.
0.99%
Monopar Therapeutics, Inc.
0.97%
Jade Biosciences, Inc.
0.94%
Aktis Oncology, Inc.
0.94%
MBX Biosciences, Inc.
0.94%
Biohaven Ltd.
0.90%
Kymera Therapeutics, Inc.
0.89%
Cullinan Therapeutics, Inc.
0.89%
SELLAS Life Sciences Group, Inc.
0.89%
Generate Biomedicines, Inc.
0.88%
Nurix Therapeutics, Inc.
0.87%
Intellia Therapeutics, Inc.
0.87%
4D Molecular Therapeutics, Inc.
0.86%
PSCH
Molina Healthcare, Inc.
5.29%
BrightSpring Health Services, Inc.
4.82%
Krystal Biotech, Inc.
4.32%
Alkermes Plc
4.06%
Glaukos Corp.
3.75%
Corcept Therapeutics, Inc.
3.69%
Protagonist Therapeutics, Inc.
3.26%
TG Therapeutics, Inc.
3.25%
PTC Therapeutics, Inc.
3.10%
Ligand Pharmaceuticals, Inc.
2.69%
Teleflex, Inc.
2.54%
Liquidia Corp.
2.43%
Indivior Pharmaceuticals, Inc.
2.25%
Veracyte, Inc.
2.13%
RadNet, Inc.
1.90%
Frequently asked questions about BBC and PSCH
How have the BBC and PSCH ETFs performed in 2026?
As of July 27, 2026, BBC is up 28.23% year-to-date (YTD), while PSCH has returned 20.01%. That puts BBC better performer ahead so far this year.
Which ETF is attracting more investor money: BBC or PSCH?
Year-to-date, the BBC ETF saw +$5M in flows, compared to -$10M for PSCH.
Which ETF is more volatile: BBC or PSCH?
Over the past year, BBC had a volatility of 35.85%, while PSCH experienced 20.1%.
Which ETF is bigger: BBC or PSCH?
As of July 27, 2026, BBC holds $47.12 M in assets under management (AUM), while PSCH manages $162.43 M.
What sectors do the BBC and PSCH ETFs invest in?
BBC leans toward sectors like Healthcare. Meanwhile, PSCH focuses on Healthcare.
What are the top holdings of the BBC ETF and PSCH ETF?
BBC top holdings include uniQure NV, REGENXBIO, Inc. and Apogee Therapeutics, Inc.. PSCH holds in its top three: Molina Healthcare, Inc., BrightSpring Health Services, Inc. and Krystal Biotech, Inc..
Which ETF is more diversified: BBC or PSCH?
BBC holds 125 securities with 14.01% of its assets in the top 15. PSCH has 75 securities and a top 15 weight of 49.48%.
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Latest news about BBC & PSCH
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