BBCvsPSCHETF Comparison
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Virtus LifeSci Biotech Clinical Trials ETF (BBC) belongs to the Tomorrow's Treatments segment. Invesco S&P SmallCap Health Care ETF (PSCH) is part of the US Health Care segment. Both ETFs have the same top 1 sector exposures: Healthcare. BBC is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.29% for PSCH. BBC is up 27.77% year-to-date (YTD) with +$5M in YTD flows. PSCH performs worse with 20.15% YTD performance, and +$7M in YTD flows. Run a side-by-side ETF comparison of BBC and PSCH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBC vs PSCH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/11/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBC PSCH | -5.78%-3.68% | +17.22%+10.91% | +27.77%+20.15% | +102.82%+27.21% | +137.50%+34.16% | +6.45%-14.30% |
| Flows | BBC PSCH | -+$5M | +$83K+$25M | +$5M+$7M | +$12M+$2M | +$16M-$109M | +$8M-$207M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBC PSCH | +33.39%+15.77% | +36.22%+19.45% | +37.22%+21.81% | +39.64%+22.88% |
| Max drawdown | BBC PSCH | -11.65%-5.62% | -14.64%-15.36% | -54.25%-22.80% | -70.43%-45.76% |
| Max drawdown duration | BBC PSCH | 23d23d | 60d168d | 340d488d | 1666d1768d |
Trading data
BBC | PSCH | |
Last sale 9/14/2026 at 1:30 PM | $49.94 | $53.33 |
| Previous close 09/11/2026 | $49.39 | $52.95 |
| Consolidated volume 09/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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BBC | PSCH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 9/14/2026 at 1:30 PM
Live
Closed
BBC | PSCH | |
|---|---|---|
| Last price | $49.94 | $53.33 |
| 1D performance | +1.12% | +0.72% |
| AuM | $46.95 M | $179.04 M |
| E/R | 0.65% | 0.29% |
Characteristics
BBC | PSCH | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | Invesco |
| Benchmark | LifeSci Biotechnology Clinical Trials Index | S&P SmallCap 600 Capped Health Care Index |
| N° of holdings | 127 | 69 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | April 7, 2010 |
| ESG | No | No |
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Exposure
Countries
BBC
USA
86.49%
Other
13.51%
PSCH
USA
95.04%
Other
4.96%
Sectors
BBC
Healthcare
95.06%
Other
4.94%
PSCH
Healthcare
100%
Other
0%
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Diversification
BBC
Total weight of top 15 holdings out of 15
15.32%
PSCH
Total weight of top 15 holdings out of 15
48.1%
Top 15 holdings
Data as of July 31, 2026
BBC
First Tracks Biotherapeutics, Inc.
1.57%
Monopar Therapeutics, Inc.
1.22%
MBX Biosciences, Inc.
1.14%
Zenas BioPharma, Inc.
1.09%
Xencor, Inc.
1.06%
Apogee Therapeutics, Inc.
1.00%
REGENXBIO, Inc.
0.96%
Oric Pharmaceuticals, Inc.
0.96%
Dyne Therapeutics, Inc.
0.93%
uniQure NV
0.91%
SELLAS Life Sciences Group, Inc.
0.91%
Nurix Therapeutics, Inc.
0.91%
Vor Biopharma, Inc.
0.89%
Erasca, Inc.
0.89%
Amylyx Pharmaceuticals, Inc.
0.88%
PSCH
Glaukos Corp.
4.96%
Corcept Therapeutics, Inc.
4.64%
Alkermes Plc
4.21%
Protagonist Therapeutics, Inc.
4.20%
TG Therapeutics, Inc.
3.68%
PTC Therapeutics, Inc.
3.23%
Liquidia Corp.
3.19%
Teleflex, Inc.
3.11%
Ligand Pharmaceuticals, Inc.
3.01%
Indivior Pharmaceuticals, Inc.
2.55%
Merit Medical Systems, Inc.
2.52%
RadNet, Inc.
2.34%
Veracyte, Inc.
2.32%
ICU Medical, Inc.
2.17%
Concentra Group Holdings Parent, Inc.
1.96%
Frequently asked questions about BBC and PSCH
How have the BBC and PSCH ETFs performed in 2026?
As of September 11, 2026, BBC is up 27.77% year-to-date (YTD), while PSCH has returned 20.15%. That puts BBC better performer ahead so far this year.
Which ETF is attracting more investor money: BBC or PSCH?
Year-to-date, the BBC ETF saw +$5M in flows, compared to +$7M for PSCH.
Which ETF is more volatile: BBC or PSCH?
Over the past year, BBC had a volatility of 36.22%, while PSCH experienced 19.45%.
Which ETF is bigger: BBC or PSCH?
As of September 11, 2026, BBC holds $46.95 M in assets under management (AUM), while PSCH manages $179.04 M.
What sectors do the BBC and PSCH ETFs invest in?
BBC leans toward sectors like Healthcare. Meanwhile, PSCH focuses on Healthcare.
What are the top holdings of the BBC ETF and PSCH ETF?
BBC top holdings include First Tracks Biotherapeutics, Inc., Monopar Therapeutics, Inc. and MBX Biosciences, Inc.. PSCH holds in its top three: Glaukos Corp., Corcept Therapeutics, Inc. and Alkermes Plc.
Which ETF is more diversified: BBC or PSCH?
BBC holds 127 securities with 15.32% of its assets in the top 15. PSCH has 69 securities and a top 15 weight of 48.1%.
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Latest news about BBC & PSCH
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