BBCvsBBPETF Comparison
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Virtus LifeSci Biotech Clinical Trials ETF (BBC) and Virtus LifeSci Biotech Products ETF (BBP) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 1 sector exposures: Healthcare. BBC is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.34% for BBP. BBC is up 13.68% year-to-date (YTD) with +$2M in YTD flows. BBP performs better with 32.94% YTD performance, and +$66M in YTD flows. Run a side-by-side ETF comparison of BBC and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBC vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/28/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBC BBP | -4.54%+0.82% | -10.21%+8.63% | +13.68%+32.94% | +39.31%+43.37% | +159.89%+129.74% | +0.98%+103.99% |
| Flows | BBC BBP | -$2M- | -$2M+$26M | +$2M+$66M | +$10M+$78M | +$14M+$83M | +$6M+$76M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBC BBP | +37.13%+28.51% | +37.04%+26.50% | +37.66%+24.95% | +40.00%+26.86% |
| Max drawdown | BBC BBP | -29.70%-8.70% | -29.70%-9.59% | -54.25%-25.54% | -70.04%-37.61% |
| Max drawdown duration | BBC BBP | 70d70d | 70d48d | 340d292d | 1625d586d |
Trading data
BBC | BBP | |
Last sale 10/28/2026 at 7:57 PM | $43.95 | $106.18 |
| Previous close 10/28/2026 | $42.87 | $104.89 |
| Consolidated volume 10/28/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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BBC | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 10/28/2026 at 7:57 PM
Live
Closed
BBC | BBP | |
|---|---|---|
| Last price | $43.95 | $106.18 |
| 1D performance | +2.51% | +1.23% |
| AuM | $39.58 M | $132.54 M |
| E/R | 0.65% | 0.34% |
Characteristics
BBC | BBP | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | VIRTUS Investment Partners |
| Benchmark | LifeSci Biotechnology Clinical Trials Index | LifeSci Biotechnology Products Index |
| N° of holdings | 127 | 66 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
BBC
USA
87.24%
Other
12.76%
BBP
USA
85.98%
Other
14.02%
Sectors
BBC
Healthcare
96.27%
Other
3.73%
BBP
Healthcare
98.44%
Other
1.56%
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Diversification
BBC
Total weight of top 15 holdings out of 15
17.14%
BBP
Total weight of top 15 holdings out of 15
31.08%
Top 15 holdings
Data as of August 31, 2026
BBC
Amylyx Pharmaceuticals, Inc.
1.50%
First Tracks Biotherapeutics, Inc.
1.48%
AbCellera Biologics, Inc.
1.38%
Xencor, Inc.
1.36%
Monopar Therapeutics, Inc.
1.12%
MBX Biosciences, Inc.
1.11%
uniQure NV
1.09%
Replimune Group, Inc.
1.06%
4D Molecular Therapeutics, Inc.
1.04%
SELLAS Life Sciences Group, Inc.
1.04%
Alto Neuroscience, Inc.
1.00%
LB Pharmaceuticals, Inc.
1.00%
Oric Pharmaceuticals, Inc.
0.99%
Zenas BioPharma, Inc.
0.98%
Cullinan Therapeutics, Inc.
0.98%
BBP
Moderna, Inc.
3.58%
Crinetics Pharmaceuticals, Inc.
2.94%
Omeros Corp.
2.49%
Iovance Biotherapeutics, Inc.
2.36%
Verastem, Inc.
2.15%
Precigen, Inc.
1.99%
Halozyme Therapeutics, Inc.
1.84%
Zai Lab Ltd.
1.82%
Kiniksa Pharmaceuticals International Plc
1.81%
Kura Oncology, Inc.
1.72%
BeOne Medicines Ltd.
1.70%
Rigel Pharmaceuticals, Inc.
1.69%
Nuvation Bio, Inc.
1.69%
ACADIA Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
Frequently asked questions about BBC and BBP
How have the BBC and BBP ETFs performed in 2026?
As of October 28, 2026, BBC is up 13.68% year-to-date (YTD), while BBP has returned 32.94%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBC or BBP?
Year-to-date, the BBC ETF saw +$2M in flows, compared to +$66M for BBP.
Which ETF is more volatile: BBC or BBP?
Over the past year, BBC had a volatility of 37.04%, while BBP experienced 26.5%.
Which ETF is bigger: BBC or BBP?
As of October 28, 2026, BBC holds $39.58 M in assets under management (AUM), while BBP manages $132.54 M.
What sectors do the BBC and BBP ETFs invest in?
BBC leans toward sectors like Healthcare. Meanwhile, BBP focuses on Healthcare.
What are the top holdings of the BBC ETF and BBP ETF?
BBC top holdings include Amylyx Pharmaceuticals, Inc., First Tracks Biotherapeutics, Inc. and AbCellera Biologics, Inc.. BBP holds in its top three: Moderna, Inc., Crinetics Pharmaceuticals, Inc. and Omeros Corp..
Which ETF is more diversified: BBC or BBP?
BBC holds 127 securities with 17.14% of its assets in the top 15. BBP has 66 securities and a top 15 weight of 31.08%.
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Latest news about BBC & BBP
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