BBCvsBBPETF Comparison
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Virtus LifeSci Biotech Clinical Trials ETF (BBC) and Virtus LifeSci Biotech Products ETF (BBP) belong to the same industry segment: Tomorrow's Treatments. Both ETFs have the same top 1 sector exposures: Healthcare. BBC is more expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.34% for BBP. BBC is up 27.77% year-to-date (YTD) with +$5M in YTD flows. BBP performs better with 29.59% YTD performance, and +$61M in YTD flows. Run a side-by-side ETF comparison of BBC and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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BBC vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/11/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | BBC BBP | -5.78%+1.58% | +17.22%+19.06% | +27.77%+29.59% | +102.82%+46.60% | +137.50%+94.97% | +6.45%+99.54% |
| Flows | BBC BBP | -+$16M | +$83K+$31M | +$5M+$61M | +$12M+$72M | +$16M+$78M | +$8M+$71M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | BBC BBP | +33.39%+25.64% | +36.22%+25.15% | +37.22%+24.71% | +39.64%+26.61% |
| Max drawdown | BBC BBP | -11.65%-9.34% | -14.64%-9.59% | -54.25%-25.54% | -70.43%-37.61% |
| Max drawdown duration | BBC BBP | 23d39d | 60d48d | 340d292d | 1666d586d |
Trading data
BBC | BBP | |
Last sale 9/11/2026 at 1:30 PM | $49.39 | $103.46 |
| Previous close 09/10/2026 | $49.91 | $103.47 |
| Consolidated volume 09/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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BBC | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 9/11/2026 at 1:30 PM
Live
Closed
BBC | BBP | |
|---|---|---|
| Last price | $49.39 | $103.46 |
| 1D performance | -1.05% | -0.01% |
| AuM | $46.95 M | $124.03 M |
| E/R | 0.65% | 0.34% |
Characteristics
BBC | BBP | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | VIRTUS Investment Partners | VIRTUS Investment Partners |
| Benchmark | LifeSci Biotechnology Clinical Trials Index | LifeSci Biotechnology Products Index |
| N° of holdings | 127 | 66 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | December 16, 2014 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
BBC
USA
86.49%
Other
13.51%
BBP
USA
86.5%
Other
13.5%
Sectors
BBC
Healthcare
95.06%
Other
4.94%
BBP
Healthcare
98.2%
Other
1.8%
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Diversification
BBC
Total weight of top 15 holdings out of 15
15.32%
BBP
Total weight of top 15 holdings out of 15
26.78%
Top 15 holdings
Data as of July 31, 2026
BBC
First Tracks Biotherapeutics, Inc.
1.57%
Monopar Therapeutics, Inc.
1.22%
MBX Biosciences, Inc.
1.14%
Zenas BioPharma, Inc.
1.09%
Xencor, Inc.
1.06%
Apogee Therapeutics, Inc.
1.00%
REGENXBIO, Inc.
0.96%
Oric Pharmaceuticals, Inc.
0.96%
Dyne Therapeutics, Inc.
0.93%
uniQure NV
0.91%
SELLAS Life Sciences Group, Inc.
0.91%
Nurix Therapeutics, Inc.
0.91%
Vor Biopharma, Inc.
0.89%
Erasca, Inc.
0.89%
Amylyx Pharmaceuticals, Inc.
0.88%
BBP
Crinetics Pharmaceuticals, Inc.
3.24%
Verastem, Inc.
1.98%
Nuvation Bio, Inc.
1.80%
Omeros Corp.
1.73%
Geron Corp.
1.72%
BridgeBio Pharma, Inc.
1.68%
Agios Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
BeOne Medicines Ltd.
1.64%
Kiniksa Pharmaceuticals International Plc
1.63%
Precigen, Inc.
1.62%
Xeris Biopharma Holdings, Inc.
1.61%
ACADIA Pharmaceuticals, Inc.
1.60%
Iovance Biotherapeutics, Inc.
1.60%
Rhythm Pharmaceuticals, Inc.
1.60%
Frequently asked questions about BBC and BBP
How have the BBC and BBP ETFs performed in 2026?
As of September 11, 2026, BBC is up 27.77% year-to-date (YTD), while BBP has returned 29.59%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: BBC or BBP?
Year-to-date, the BBC ETF saw +$5M in flows, compared to +$61M for BBP.
Which ETF is more volatile: BBC or BBP?
Over the past year, BBC had a volatility of 36.22%, while BBP experienced 25.15%.
Which ETF is bigger: BBC or BBP?
As of September 11, 2026, BBC holds $46.95 M in assets under management (AUM), while BBP manages $124.03 M.
What sectors do the BBC and BBP ETFs invest in?
BBC leans toward sectors like Healthcare. Meanwhile, BBP focuses on Healthcare.
What are the top holdings of the BBC ETF and BBP ETF?
BBC top holdings include First Tracks Biotherapeutics, Inc., Monopar Therapeutics, Inc. and MBX Biosciences, Inc.. BBP holds in its top three: Crinetics Pharmaceuticals, Inc., Verastem, Inc. and Nuvation Bio, Inc..
Which ETF is more diversified: BBC or BBP?
BBC holds 127 securities with 15.32% of its assets in the top 15. BBP has 66 securities and a top 15 weight of 26.78%.
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Latest news about BBC & BBP
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