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BBCvsARKGETF Comparison

ETF 1
BBC

Virtus LifeSci Biotech Clinical Trials ETF

This fund is part of
Tomorrow's Treatments
-0.71%
VS
ETF 2
ARKG

ARK Genomic Revolution ETF

This fund is part of
BioTech & Genomics
+0.29%

Virtus LifeSci Biotech Clinical Trials ETF (BBC) belongs to the Tomorrow's Treatments segment. ARK Genomic Revolution ETF (ARKG) is part of the BioTech & Genomics segment. Both ETFs have the same top 1 sector exposures: Healthcare. BBC is less expensive with a Total Expense Ratio (TER) of 0.65%, versus 0.75% for ARKG. BBC is up 27.77% year-to-date (YTD) with +$5M in YTD flows. ARKG performs better with 55.92% YTD performance, and +$33M in YTD flows. Run a side-by-side ETF comparison of BBC and ARKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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BBC vs ARKG performance and flow charts

Performance

-50510%Aug 11Aug 18Aug 25Sep 1Sep 8

Cumulative Flows

0 M50 M100 M150 M200 MAug 11Aug 18Aug 25Sep 1Sep 8

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Historic performance and flows
Data as of 09/11/2026
1M3MYTD1Y3Y5Y
Perf.
BBC
ARKG
-5.78%+2.07%
+17.22%+35.35%
+27.77%+55.92%
+102.82%+73.72%
+137.50%+44.39%
+6.45%-43.98%
Flows
BBC
ARKG
-+$57M
+$83K+$127M
+$5M+$33M
+$12M+$51M
+$16M-$523M
+$8M-$2.24B
Volatility and drawdown
3M1Y3Y5Y
Volatility
BBC
ARKG
+33.39%+42.98%
+36.22%+43.87%
+37.22%+43.91%
+39.64%+46.35%
Max drawdown
BBC
ARKG
-11.65%-13.89%
-14.64%-27.52%
-54.25%-46.41%
-70.43%-78.04%
Max drawdown duration
BBC
ARKG
23d32d
60d126d
340d882d
1666d1818d
Trading data

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BBC
ARKG
Last sale
9/14/2026 at 1:30 PM
$49.94
$46.80
Previous close
09/11/2026
$49.39
$45.56
Consolidated volume
09/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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ARKG
is actively managed and doesn’t replicate an index

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BBC
ARKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 9/14/2026 at 1:30 PM
Live
Closed
BBC
ARKG
Last price
$49.94
$46.80
1D performance
+1.12%
+2.72%
AuM$46.95 M$1.83 B
E/R0.65%0.75%
Characteristics
BBC
ARKG
Management strategyPassiveActive
ProviderVIRTUS Investment PartnersArk Investment
BenchmarkLifeSci Biotechnology Clinical Trials Index-
N° of holdings12731
Asset classEquities-
Trailing 12m distribution yield
Join
Join
Inception dateDecember 16, 2014April 2, 2019
ESGNoNo
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Exposure

Countries

BBC
USA
86.49%
Other
13.51%
ARKG
USA
88.43%
Other
11.57%

Sectors

BBC
Healthcare
95.06%
Other
4.94%
ARKG
Healthcare
97.99%
Other
2.01%
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Diversification

BBC

Total weight of top 15 holdings out of 15

15.32%
ARKG

Total weight of top 15 holdings out of 15

75.55%

Top 15 holdings

Data as of July 31, 2026
BBC
First Tracks Biotherapeutics, Inc.
1.57%
Monopar Therapeutics, Inc.
1.22%
MBX Biosciences, Inc.
1.14%
Zenas BioPharma, Inc.
1.09%
Xencor, Inc.
1.06%
Apogee Therapeutics, Inc.
1.00%
REGENXBIO, Inc.
0.96%
Oric Pharmaceuticals, Inc.
0.96%
Dyne Therapeutics, Inc.
0.93%
uniQure NV
0.91%
SELLAS Life Sciences Group, Inc.
0.91%
Nurix Therapeutics, Inc.
0.91%
Vor Biopharma, Inc.
0.89%
Erasca, Inc.
0.89%
Amylyx Pharmaceuticals, Inc.
0.88%
ARKG
10X Genomics, Inc.
9.41%
Twist Bioscience Corp.
7.74%
Tempus AI, Inc.
6.57%
CRISPR Therapeutics AG
6.30%
Personalis, Inc.
5.48%
Absci Corp.
5.15%
Guardant Health, Inc.
4.75%
Illumina, Inc.
4.75%
Eli Lilly & Co.
4.69%
CareDx, Inc.
4.31%
Natera, Inc.
4.14%
Beam Therapeutics, Inc.
3.78%
Compass Pathways Plc
3.26%
Recursion Pharmaceuticals, Inc.
2.63%
Adaptive Biotechnologies Corp.
2.58%
Frequently asked questions about BBC and ARKG

How have the BBC and ARKG ETFs performed in 2026?

As of September 11, 2026, BBC is up 27.77% year-to-date (YTD), while ARKG has returned 55.92%. That puts ARKG better performer ahead so far this year.

Which ETF is attracting more investor money: BBC or ARKG?

Year-to-date, the BBC ETF saw +$5M in flows, compared to +$33M for ARKG.

Which ETF is more volatile: BBC or ARKG?

Over the past year, BBC had a volatility of 36.22%, while ARKG experienced 43.87%.

Which ETF is bigger: BBC or ARKG?

As of September 11, 2026, BBC holds $46.95 M in assets under management (AUM), while ARKG manages $1.83 B.

What sectors do the BBC and ARKG ETFs invest in?

BBC leans toward sectors like Healthcare. Meanwhile, ARKG focuses on Healthcare.

What are the top holdings of the BBC ETF and ARKG ETF?

BBC top holdings include First Tracks Biotherapeutics, Inc., Monopar Therapeutics, Inc. and MBX Biosciences, Inc.. ARKG holds in its top three: 10X Genomics, Inc., Twist Bioscience Corp. and Tempus AI, Inc..

Which ETF is more diversified: BBC or ARKG?

BBC holds 127 securities with 15.32% of its assets in the top 15. ARKG has 31 securities and a top 15 weight of 75.55%.

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