ARKGvsXPHETF Comparison
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ARK Genomic Revolution ETF (ARKG) belongs to the BioTech & Genomics segment. State Street SPDR S&P Pharmaceuticals ETF (XPH) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Healthcare. ARKG is more expensive with a Total Expense Ratio (TER) of 0.75%, versus 0.35% for XPH. ARKG is up 29.47% year-to-date (YTD) with +$39M in YTD flows. XPH performs worse with 21.25% YTD performance, and +$175M in YTD flows. Run a side-by-side ETF comparison of ARKG and XPH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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ARKG vs XPH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | ARKG XPH | -1.87%+5.40% | +27.92%+18.17% | +29.47%+21.25% | +45.31%+57.72% | +4.16%+66.18% | -54.66%+39.78% |
| Flows | ARKG XPH | +$81M+$74M | +$62M+$60M | +$39M+$175M | -$3M+$200M | -$550M+$128M | -$2.57B+$141M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | ARKG XPH | +44.86%+24.45% | +42.64%+22.22% | +43.40%+20.31% | +45.98%+20.88% |
| Max drawdown | ARKG XPH | -13.14%-8.13% | -27.52%-11.78% | -51.67%-23.45% | -79.29%-31.59% |
| Max drawdown duration | ARKG XPH | 18d41d | 126d50d | 1058d322d | 1814d1566d |
Trading data
ARKG | XPH | |
Last sale 7/27/2026 at 1:30 PM | $37.75 | $68.52 |
| Previous close 07/24/2026 | $37.81 | $67.95 |
| Consolidated volume 07/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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ARKG
is actively managed and doesn’t replicate an indexARKG | XPH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
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Main metrics
Last update 7/27/2026 at 1:30 PM
Live
Closed
ARKG | XPH | |
|---|---|---|
| Last price | $37.75 | $68.52 |
| 1D performance | -0.16% | +0.84% |
| AuM | $1.53 B | $475.04 M |
| E/R | 0.75% | 0.35% |
Characteristics
ARKG | XPH | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Ark Investment | State Street Investment Management |
| Benchmark | - | S&P Pharmaceuticals Select Industry Index |
| N° of holdings | 31 | 63 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 2, 2019 | June 19, 2006 |
| ESG | No | No |
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Exposure
Countries
ARKG
USA
86.99%
Other
13.01%
XPH
USA
90.15%
Other
9.85%
Sectors
ARKG
Healthcare
96.93%
Other
3.07%
XPH
Healthcare
94.73%
Other
5.27%
Diversification
ARKG
Total weight of top 15 holdings out of 15
74.95%
XPH
Total weight of top 15 holdings out of 15
29.74%
Top 15 holdings
Data as of June 30, 2026
ARKG
Twist Bioscience Corp.
9.15%
Tempus AI, Inc.
7.64%
Absci Corp.
7.01%
10X Genomics, Inc.
7.00%
CRISPR Therapeutics AG
6.56%
Personalis, Inc.
6.19%
Beam Therapeutics, Inc.
4.34%
Guardant Health, Inc.
4.28%
Natera, Inc.
4.11%
Illumina, Inc.
3.98%
Veracyte, Inc.
3.24%
CareDx, Inc.
3.08%
Recursion Pharmaceuticals, Inc.
2.85%
Eli Lilly & Co.
2.81%
Compass Pathways Plc
2.70%
XPH
MBX Biosciences, Inc.
2.72%
Alumis, Inc.
2.14%
Trevi Therapeutics, Inc.
2.12%
Enliven Therapeutics, Inc.
2.09%
Amylyx Pharmaceuticals, Inc.
2.04%
Veradermics, Inc.
2.02%
Ligand Pharmaceuticals, Inc.
1.94%
Nuvation Bio, Inc.
1.89%
Edgewise Therapeutics, Inc.
1.88%
Nektar Therapeutics
1.88%
Liquidia Corp.
1.86%
Maze Therapeutics, Inc.
1.85%
Harrow, Inc.
1.81%
EyePoint, Inc.
1.77%
Amneal Pharmaceuticals, Inc.
1.72%
Frequently asked questions about ARKG and XPH
How have the ARKG and XPH ETFs performed in 2026?
As of July 24, 2026, ARKG is up 29.47% year-to-date (YTD), while XPH has returned 21.25%. That puts ARKG better performer ahead so far this year.
Which ETF is attracting more investor money: ARKG or XPH?
Year-to-date, the ARKG ETF saw +$39M in flows, compared to +$175M for XPH.
Which ETF is more volatile: ARKG or XPH?
Over the past year, ARKG had a volatility of 42.64%, while XPH experienced 22.22%.
Which ETF is bigger: ARKG or XPH?
As of July 24, 2026, ARKG holds $1.53 B in assets under management (AUM), while XPH manages $475.04 M.
What sectors do the ARKG and XPH ETFs invest in?
ARKG leans toward sectors like Healthcare. Meanwhile, XPH focuses on Healthcare.
What are the top holdings of the ARKG ETF and XPH ETF?
ARKG top holdings include Twist Bioscience Corp., Tempus AI, Inc. and Absci Corp.. XPH holds in its top three: MBX Biosciences, Inc., Alumis, Inc. and Trevi Therapeutics, Inc..
Which ETF is more diversified: ARKG or XPH?
ARKG holds 31 securities with 74.95% of its assets in the top 15. XPH has 63 securities and a top 15 weight of 29.74%.
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