ARKGvsXPHETF Comparison
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ARK Genomic Revolution ETF (ARKG) belongs to the BioTech & Genomics segment. State Street SPDR S&P Pharmaceuticals ETF (XPH) is part of the US Health Care segment. ARKG's top 3 sector exposures are Health Care and Information Technology. In contrast, XPH's top sector exposures are Health Care ARKG is more expensive with a Total Expense Ratio (TER) of 0.75%, versus 0.35% for XPH. ARKG is up 2.37% year-to-date (YTD) with +$35M in YTD flows. XPH performs better with 4.54% YTD performance, and +$116M in YTD flows. Run a side-by-side ETF comparison of ARKG and XPH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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ARKG vs XPH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/30/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | ARKG XPH | +20.56%+7.12% | -1.72%+2.92% | +2.37%+4.54% | +35.83%+46.34% | +2.31%+43.33% | -66.16%+26.51% |
| Flows | ARKG XPH | +$50M+$25M | +$8M+$54M | +$35M+$116M | -$14M+$141M | -$531M+$48M | -$3.01B+$74M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | ARKG XPH | +43.80%+24.27% | +41.90%+21.12% | +42.68%+19.51% | +45.42%+20.49% |
| Max drawdown | ARKG XPH | -19.13%-11.78% | -27.52%-11.78% | -51.98%-23.45% | -80.16%-31.59% |
| Max drawdown duration | ARKG XPH | 73d50d | 98d50d | 1016d322d | 1766d1566d |
Trading data
ARKG | XPH | |
Last sale 5/1/2026 at 1:30 PM | $30.30 | $58.49 |
| Previous close 04/29/2026 | $29.87 | $57.61 |
| Consolidated volume 04/29/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of April 30, 2026
1-year trailing difference
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ARKG
is actively managed and doesn’t replicate an indexARKG | XPH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 5/1/2026 at 1:30 PM
Live
Closed
ARKG | XPH | |
|---|---|---|
| Last price | $30.30 | $58.49 |
| 1D performance | +1.44% | +1.53% |
| AuM | $1.24 B | $360.20 M |
| E/R | 0.75% | 0.35% |
Characteristics
ARKG | XPH | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Ark Investment | State Street Investment Management |
| Benchmark | - | S&P Pharmaceuticals Select Industry Index |
| N° of holdings | 27 | 48 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 2, 2019 | June 19, 2006 |
| ESG | No | No |
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Exposure
Countries
ARKG
USA
70.4%
Switzerland
9.23%
Other
20.37%
XPH
USA
87.77%
Other
12.23%
Sectors
ARKG
Health Care
78.38%
Other
21.62%
XPH
Health Care
82.36%
Other
17.64%
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Diversification
ARKG
Total weight of top 15 holdings out of 15
62.5%
XPH
Total weight of top 15 holdings out of 15
30.65%
Top 15 holdings
Data as of March 31, 2026
ARKG
CRISPR THERAPEUTICS
9.23%
10X GENOMICS INC
6.30%
BEAM THERAPEUTICS
4.86%
PERSONALIS INC
4.69%
NATERA
4.48%
ILLUMINA
4.45%
GUARDANT HEALTH INC
4.21%
INTELLIA THERAPEUTICS INC
3.58%
CAREDX INC/D
3.56%
RECURSION PHARMACEUTICALS
3.54%
ABSCI
3.27%
VERACYTE INC/D
2.98%
ADAPTIVE BIOTECHNOLOGIES
2.71%
NURIX THERAPEUTICS
2.45%
SEMA4 HOLDINGS CORP
2.19%
XPH
US29337E1029
2.45%
CORCEPT THERAPEUTICS
2.29%
TERNS PHARMACEUTICALS
2.16%
PERRIGO CO PLC
2.10%
AXSOME THERA CMN STK
2.03%
INNOVIVA INC
1.99%
MERCK & CO INC
1.98%
PFIZER
1.97%
ROYALTY PHARMA
1.97%
ELANCO ANIMAL HEALTH INC
1.96%
JAZZ PHARMACEUTICALS
1.96%
ESPERION THERAPEUTICS
1.95%
EDGEWISE THERAPEUTICS
1.95%
US55287L1017
1.95%
BRISTOL-MYERS SQUIBB
1.94%
Frequently asked questions about ARKG and XPH
How have the ARKG and XPH ETFs performed in 2026?
As of April 30, 2026, ARKG is up 2.37% year-to-date (YTD), while XPH has returned 4.54%. That puts XPH better performer ahead so far this year.
Which ETF is attracting more investor money: ARKG or XPH?
Year-to-date, the ARKG ETF saw +$35M in flows, compared to +$116M for XPH.
Which ETF is more volatile: ARKG or XPH?
Over the past year, ARKG had a volatility of 41.9%, while XPH experienced 21.12%.
Which ETF is bigger: ARKG or XPH?
As of April 30, 2026, ARKG holds $1.24 B in assets under management (AUM), while XPH manages $360.20 M.
What sectors do the ARKG and XPH ETFs invest in?
ARKG leans toward sectors like Health Care. Meanwhile, XPH focuses on Health Care.
What are the top holdings of the ARKG ETF and XPH ETF?
ARKG top holdings include CRISPR THERAPEUTICS, 10X GENOMICS INC and BEAM THERAPEUTICS. XPH holds in its top three: US29337E1029, CORCEPT THERAPEUTICS and TERNS PHARMACEUTICALS.
Which ETF is more diversified: ARKG or XPH?
ARKG holds 27 securities with 62.5% of its assets in the top 15. XPH has 57 securities and a top 15 weight of 30.65%.
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