ARKGvsBBCETF Comparison
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ARK Genomic Revolution ETF (ARKG) belongs to the BioTech & Genomics segment. Virtus LifeSci Biotech Clinical Trials ETF (BBC) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 1 sector exposures: Healthcare. ARKG is more expensive with a Total Expense Ratio (TER) of 0.75%, versus 0.65% for BBC. ARKG is up 55.92% year-to-date (YTD) with +$33M in YTD flows. BBC performs worse with 27.77% YTD performance, and +$5M in YTD flows. Run a side-by-side ETF comparison of ARKG and BBC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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ARKG vs BBC performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/11/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | ARKG BBC | +2.07%-5.78% | +35.35%+17.22% | +55.92%+27.77% | +73.72%+102.82% | +44.39%+137.50% | -43.98%+6.45% |
| Flows | ARKG BBC | +$57M- | +$127M+$83K | +$33M+$5M | +$51M+$12M | -$523M+$16M | -$2.24B+$8M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | ARKG BBC | +42.98%+33.39% | +43.87%+36.22% | +43.91%+37.22% | +46.35%+39.64% |
| Max drawdown | ARKG BBC | -13.89%-11.65% | -27.52%-14.64% | -46.41%-54.25% | -78.04%-70.43% |
| Max drawdown duration | ARKG BBC | 32d23d | 126d60d | 882d340d | 1818d1666d |
Trading data
ARKG | BBC | |
Last sale 9/11/2026 at 1:30 PM | $45.56 | $49.39 |
| Previous close 09/10/2026 | $45.38 | $49.91 |
| Consolidated volume 09/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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ARKG
is actively managed and doesn’t replicate an indexARKG | BBC | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/11/2026 at 1:30 PM
Live
Closed
ARKG | BBC | |
|---|---|---|
| Last price | $45.56 | $49.39 |
| 1D performance | +0.40% | -1.05% |
| AuM | $1.83 B | $46.95 M |
| E/R | 0.75% | 0.65% |
Characteristics
ARKG | BBC | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | Ark Investment | VIRTUS Investment Partners |
| Benchmark | - | LifeSci Biotechnology Clinical Trials Index |
| N° of holdings | 31 | 127 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 2, 2019 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
ARKG
USA
88.43%
Other
11.57%
BBC
USA
86.49%
Other
13.51%
Sectors
ARKG
Healthcare
97.99%
Other
2.01%
BBC
Healthcare
95.06%
Other
4.94%
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Diversification
ARKG
Total weight of top 15 holdings out of 15
75.55%
BBC
Total weight of top 15 holdings out of 15
15.32%
Top 15 holdings
Data as of July 31, 2026
ARKG
10X Genomics, Inc.
9.41%
Twist Bioscience Corp.
7.74%
Tempus AI, Inc.
6.57%
CRISPR Therapeutics AG
6.30%
Personalis, Inc.
5.48%
Absci Corp.
5.15%
Guardant Health, Inc.
4.75%
Illumina, Inc.
4.75%
Eli Lilly & Co.
4.69%
CareDx, Inc.
4.31%
Natera, Inc.
4.14%
Beam Therapeutics, Inc.
3.78%
Compass Pathways Plc
3.26%
Recursion Pharmaceuticals, Inc.
2.63%
Adaptive Biotechnologies Corp.
2.58%
BBC
First Tracks Biotherapeutics, Inc.
1.57%
Monopar Therapeutics, Inc.
1.22%
MBX Biosciences, Inc.
1.14%
Zenas BioPharma, Inc.
1.09%
Xencor, Inc.
1.06%
Apogee Therapeutics, Inc.
1.00%
REGENXBIO, Inc.
0.96%
Oric Pharmaceuticals, Inc.
0.96%
Dyne Therapeutics, Inc.
0.93%
uniQure NV
0.91%
SELLAS Life Sciences Group, Inc.
0.91%
Nurix Therapeutics, Inc.
0.91%
Vor Biopharma, Inc.
0.89%
Erasca, Inc.
0.89%
Amylyx Pharmaceuticals, Inc.
0.88%
Frequently asked questions about ARKG and BBC
How have the ARKG and BBC ETFs performed in 2026?
As of September 11, 2026, ARKG is up 55.92% year-to-date (YTD), while BBC has returned 27.77%. That puts ARKG better performer ahead so far this year.
Which ETF is attracting more investor money: ARKG or BBC?
Year-to-date, the ARKG ETF saw +$33M in flows, compared to +$5M for BBC.
Which ETF is more volatile: ARKG or BBC?
Over the past year, ARKG had a volatility of 43.87%, while BBC experienced 36.22%.
Which ETF is bigger: ARKG or BBC?
As of September 11, 2026, ARKG holds $1.83 B in assets under management (AUM), while BBC manages $46.95 M.
What sectors do the ARKG and BBC ETFs invest in?
ARKG leans toward sectors like Healthcare. Meanwhile, BBC focuses on Healthcare.
What are the top holdings of the ARKG ETF and BBC ETF?
ARKG top holdings include 10X Genomics, Inc., Twist Bioscience Corp. and Tempus AI, Inc.. BBC holds in its top three: First Tracks Biotherapeutics, Inc., Monopar Therapeutics, Inc. and MBX Biosciences, Inc..
Which ETF is more diversified: ARKG or BBC?
ARKG holds 31 securities with 75.55% of its assets in the top 15. BBC has 127 securities and a top 15 weight of 15.32%.
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Latest news about ARKG & BBC
Small-Cap Biotech ETFs: High-Risk, High-Reward Opportunities
September 18, 2025
BBC
Biotech ETFs – Investing in Health Innovation
July 21, 2022
ARKG
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