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AGNGvsMEDXETF Comparison

ETF 1

AGNG

Global X Aging Population ETF

This fund is part of

New Consumers & Focus

-0.87%

Full AGNG fund page

VS

ETF 2

MEDX

Horizon Kinetics Medical ETF

This fund is part of

Tomorrow's Treatments

-0.9%

Full MEDX fund page

Global X Aging Population ETF (AGNG) belongs to the New Consumers & Focus segment. Horizon Kinetics Medical ETF (MEDX) is part of the Tomorrow's Treatments segment. AGNG's top 3 sector exposures are Health Care and Real Estate. In contrast, MEDX's top sector exposures are Health Care AGNG is less expensive with a Total Expense Ratio (TER) of 0.5%, versus 0.85% for MEDX. AGNG is down -2.61% year-to-date (YTD) with +$12M in YTD flows. MEDX performs worse with -3.86% YTD performance, and -$799K in YTD flows. Run a side-by-side ETF comparison of AGNG and MEDX below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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AGNG vs MEDX performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/28/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	AGNG MEDX	-0.04%-1.24%	-5.23%-4.41%	-2.61%-3.86%	+13.71%+22.09%	+26.97%+14.33%	+24.20%n/a
Flows	AGNG MEDX	-$16K-	+$2M-$799K	+$12M-$799K	+$18M-$2M	+$4M-$3M	+$30M-

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	AGNG MEDX	+13.74%+19.22%	+12.54%+18.68%	+11.78%+16.64%	+13.58%n/a
Max drawdown	AGNG MEDX	-10.02%-10.13%	-10.02%-10.13%	-13.73%-23.05%	-25.40%n/a
Max drawdown duration	AGNG MEDX	58d58d	58d58d	323d393d	1041dn/a

Trading data

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	AGNG	MEDX
Last sale 4/29/2026 at 1:30 PM	$34.35	$31.94
Previous close 04/28/2026	$34.91	$31.95
Consolidated volume 04/28/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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MEDX

is actively managed and doesn’t replicate an index

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	AGNG	MEDX
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/29/2026 at 1:30 PM

Live

Closed

	AGNG	MEDX
Last price	$34.35	$31.94
1D performance	-1.62%	-0.02%
AuM	$81.29 M	$17.42 M
E/R	0.5%	0.85%

Characteristics

	AGNG	MEDX
Management strategy	Passive	Active
Provider	Global X	Horizon Kinetics LLC
Benchmark	Indxx Aging Population Thematic Index	-
N° of holdings	75	25
Asset class	-	-
Trailing 12m distribution yield	Join	Join
Inception date	May 9, 2016	January 27, 2023
ESG	Yes	No

More AGNG data on Trackinsight

More MEDX data on Trackinsight

Exposure

Countries

AGNG

USA

56.85%

Switzerland

10.41%

Other

32.74%

MEDX

USA

79.24%

Other

20.76%

Sectors

AGNG

Health Care

84.44%

Real Estate

8.29%

Other

7.27%

MEDX

Health Care

79%

Other

21%

Diversification

AGNG

Total weight of top 15 holdings out of 15

49.52%

MEDX

Total weight of top 15 holdings out of 15

82.03%

Top 15 holdings

Data as of March 31, 2026

AGNG

UCB

4.53%

JOHNSON&JOHNSON

4.04%

MERCK & CO INC

3.74%

ASTRAZENECA

3.73%

WELLTOWER INC

3.58%

REGENERON PHARMACEUTICALS

3.36%

ROCHE

3.28%

AMGEN-T

3.11%

CHUGAI PHARMACEUTICAL

3.06%

LILLY

3.05%

ABBVIE

3.03%

EDWARDS LIFESCIENCES

2.96%

BRISTOL-MYERS SQUIBB

2.81%

MEDTRONIC PLC

2.62%

VENTAS REIT

2.59%

MEDX

LILLY

15.47%

ABBVIE

8.50%

US66987V1098

7.50%

JOHNSON&JOHNSON

6.05%

ASTRAZENECA

5.78%

BRISTOL-MYERS SQUIBB

5.20%

IONIS PHARMACEUTICALS INC

4.70%

AMGEN-T

4.28%

MERCK & CO INC

4.12%

ALNYLAM PHARMACEUTICALS

4.07%

PFIZER

3.74%

ALKERMES

3.61%

US37733W2044

3.17%

BIOGEN INC

3.04%

REGENERON PHARMACEUTICALS

2.80%

Frequently asked questions about AGNG and MEDX

How have the AGNG and MEDX ETFs performed in 2026?

As of April 28, 2026, AGNG is down -2.61% year-to-date (YTD), while MEDX has lost -3.86%. That puts AGNG better performer ahead so far this year.

Which ETF is attracting more investor money: AGNG or MEDX?

Year-to-date, the AGNG ETF saw +$12M in flows, compared to -$799K for MEDX.

Which ETF is more volatile: AGNG or MEDX?

Over the past year, AGNG had a volatility of 12.54%, while MEDX experienced 18.68%.

Which ETF is bigger: AGNG or MEDX?

As of April 28, 2026, AGNG holds $81.29 M in assets under management (AUM), while MEDX manages $17.42 M.

What sectors do the AGNG and MEDX ETFs invest in?

AGNG leans toward sectors like Health Care and Real Estate. Meanwhile, MEDX focuses on Health Care.

What are the top holdings of the AGNG ETF and MEDX ETF?

AGNG top holdings include UCB, JOHNSON&JOHNSON and MERCK & CO INC. MEDX holds in its top three: LILLY, ABBVIE and US66987V1098.

Which ETF is more diversified: AGNG or MEDX?

AGNG holds 78 securities with 49.52% of its assets in the top 15. MEDX has 29 securities and a top 15 weight of 82.03%.

Investing in the Aging Demographics Megatrend

February 28, 2023

AGNG

AGNGvsMEDXETF Comparison

Global X Aging Population ETF

Horizon Kinetics Medical ETF

AGNG vs MEDX performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the AGNG and MEDX ETFs performed in 2026?

As of April 28, 2026, AGNG is down -2.61% year-to-date (YTD), while MEDX has lost -3.86%. That puts AGNG better performer ahead so far this year.

Which ETF is attracting more investor money: AGNG or MEDX?

Year-to-date, the AGNG ETF saw +$12M in flows, compared to -$799K for MEDX.

Which ETF is more volatile: AGNG or MEDX?

Over the past year, AGNG had a volatility of 12.54%, while MEDX experienced 18.68%.

Which ETF is bigger: AGNG or MEDX?

As of April 28, 2026, AGNG holds $81.29 M in assets under management (AUM), while MEDX manages $17.42 M.

What sectors do the AGNG and MEDX ETFs invest in?

AGNG leans toward sectors like Health Care and Real Estate. Meanwhile, MEDX focuses on Health Care.

What are the top holdings of the AGNG ETF and MEDX ETF?

AGNG top holdings include UCB, JOHNSON&JOHNSON and MERCK & CO INC. MEDX holds in its top three: LILLY, ABBVIE and US66987V1098.

Which ETF is more diversified: AGNG or MEDX?

AGNG holds 78 securities with 49.52% of its assets in the top 15. MEDX has 29 securities and a top 15 weight of 82.03%.

Investing in the Aging Demographics Megatrend

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