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XLVIvsTMEDETF Comparison

ETF 1
XLVI

The Health Care Select Sector SPDR Premium Income Fund

This fund is part of
Options Strategies
-0.04%
Full XLVI fund page
VS
ETF 2
TMED

T. Rowe Price Health Care ETF

This fund is part of
US Health Care
-0.31%
Full TMED fund page

The Health Care Select Sector SPDR Premium Income Fund (XLVI) belongs to the Options Strategies segment. T. Rowe Price Health Care ETF (TMED) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. XLVI is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.44% for TMED. XLVI is up 0.28% year-to-date (YTD) with +$2M in YTD flows. TMED performs worse with 0.13% YTD performance, and +$3M in YTD flows. Run a side-by-side ETF comparison of XLVI and TMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XLVI vs TMED performance and flow charts

Performance

-1.00.01.02.03.04.0%Feb 10Feb 18Feb 25Mar 4Mar 11

Cumulative Flows

0 M0.5 M1 M1.5 M2 M2.5 M3 MFeb 10Feb 18Feb 25Mar 4Mar 11

Get all the metrics on this page, and more, through a reliable ETF data feed

Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
XLVI
TMED
-1.07%+1.16%
+1.89%+1.57%
+0.28%+0.13%
n/an/a
n/an/a
n/an/a
Flows
XLVI
TMED
+$788K+$1M
+$3M+$4M
+$2M+$3M
--
--
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
XLVI
TMED
+10.15%+16.57%
n/an/a
n/an/a
n/an/a
Max drawdown
XLVI
TMED
-3.26%-7.14%
n/an/a
n/an/a
n/an/a
Max drawdown duration
XLVI
TMED
10d47d
n/an/a
n/an/a
n/an/a
Trading data

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XLVI
TMED
Last sale
3/11/2026 at 7:59 PM
$25.92
$28.95
Previous close
03/11/2026
$25.98
$29.57
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
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Main metrics
Last update 3/11/2026 at 7:59 PM
Live
Closed
XLVI
TMED
Last price
$25.92
$28.95
1D performance
-0.23%
-2.11%
AuM$13.24 M$19.32 M
E/R0.35%0.44%
Characteristics
XLVI
TMED
Management strategyActiveActive
ProviderSPDRT. Rowe Price
Benchmark--
N° of holdings5774
Asset class--
Trailing 12m distribution yield
Join
Join
Inception dateJuly 30, 2025June 11, 2025
ESGNoNo
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Exposure

Countries

XLVI
USA
96.37%
Other
3.63%
TMED
USA
85.25%
Other
14.75%

Sectors

XLVI
Health Care
97.65%
Other
2.35%
TMED
Health Care
86.52%
Other
13.48%
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Diversification

XLVI

Total weight of top 15 holdings out of 15

69.69%
TMED

Total weight of top 15 holdings out of 15

56.46%

Top 15 holdings

Data as of January 31, 2026
XLVI
LILLY
14.60%
JOHNSON&JOHNSON
9.71%
ABBVIE
6.99%
MERCK & CO INC
4.85%
UNITEDHEALTH GRP
4.61%
THERMO FISHER SCIENTIFIC
3.85%
ABBOTT LABS
3.37%
AMGEN-T
3.26%
INTUITIVE SURGICAL
3.17%
GILEAD SCIENCES
3.12%
PFIZER
2.66%
BOSTON SCIENTIFIC
2.46%
DANAHER
2.44%
MEDTRONIC PLC
2.34%
STRYKER
2.25%
TMED
LILLY
15.36%
UNITEDHEALTH GRP
6.90%
GILEAD SCIENCES
4.56%
ABBOTT LABS
4.23%
THERMO FISHER SCIENTIFIC
3.98%
DANAHER
3.15%
BECTON DICKINSON AND CO
2.59%
ELANCO ANIMAL HEALTH INC
2.53%
CYTOKINETICS
2.50%
MEDTRONIC PLC
2.22%
ERASCA
1.89%
AMERISOURCEBERGEN
1.78%
STRYKER
1.67%
ARCELLX
1.57%
DYNE THERAPEUTICS INC
1.53%
Frequently asked questions about XLVI and TMED

How have the XLVI and TMED ETFs performed in 2026?

As of March 11, 2026, XLVI is up 0.28% year-to-date (YTD), while TMED has returned 0.13%. That puts XLVI better performer ahead so far this year.

Which ETF is attracting more investor money: XLVI or TMED?

Year-to-date, the XLVI ETF saw +$2M in flows, compared to +$3M for TMED.

Which ETF is bigger: XLVI or TMED?

As of March 11, 2026, XLVI holds $13.24 M in assets under management (AUM), while TMED manages $19.32 M.

What sectors do the XLVI and TMED ETFs invest in?

XLVI leans toward sectors like Health Care. Meanwhile, TMED focuses on Health Care.

What are the top holdings of the XLVI ETF and TMED ETF?

XLVI top holdings include LILLY, JOHNSON&JOHNSON and ABBVIE. TMED holds in its top three: LILLY, UNITEDHEALTH GRP and GILEAD SCIENCES.

Which ETF is more diversified: XLVI or TMED?

XLVI holds 60 securities with 69.69% of its assets in the top 15. TMED has 80 securities and a top 15 weight of 56.46%.

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