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XLVIvsTMEDETF Comparison

ETF 1

XLVI

State Street Health Care Select Sector SPDR Premium Income Fund

This fund is part of

Options Strategies

-0.18%

Full XLVI fund page

VS

ETF 2

TMED

T. Rowe Price Health Care ETF

This fund is part of

US Health Care

+1.38%

Full TMED fund page

State Street Health Care Select Sector SPDR Premium Income Fund (XLVI) belongs to the Options Strategies segment. T. Rowe Price Health Care ETF (TMED) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. XLVI is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.44% for TMED. XLVI is up 2.13% year-to-date (YTD) with +$4M in YTD flows. TMED performs better with 5.76% YTD performance, and +$3M in YTD flows. Run a side-by-side ETF comparison of XLVI and TMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XLVI vs TMED performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 06/09/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	XLVI TMED	+6.44%+3.81%	+1.06%+4.78%	+2.13%+5.76%	n/a+26.55%	n/an/a	n/an/a
Flows	XLVI TMED	+$2M-$2M	+$2M-$53K	+$4M+$3M	-+$17M	--	--

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	XLVI TMED	+13.59%+21.31%	n/a+18.08%	n/an/a	n/an/a
Max drawdown	XLVI TMED	-6.06%-7.71%	n/a-11.09%	n/an/a	n/an/a
Max drawdown duration	XLVI TMED	86d29d	n/a125d	n/an/a	n/an/a

Trading data

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	XLVI	TMED
Last sale 6/10/2026 at 1:30 PM	$25.50	$31.40
Previous close 06/09/2026	$25.60	$31.97
Consolidated volume 06/09/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Main metrics

Last update 6/10/2026 at 1:30 PM

Live

Closed

	XLVI	TMED
Last price	$25.50	$31.40
1D performance	-0.38%	-1.77%
AuM	$14.84 M	$20.40 M
E/R	0.35%	0.44%

Characteristics

	XLVI	TMED
Management strategy	Active	Active
Provider	State Street Investment Management	T. Rowe Price
Benchmark	-	-
N° of holdings	55	74
Asset class	-	-
Trailing 12m distribution yield	Join	Join
Inception date	July 30, 2025	June 11, 2025
ESG	No	No

More XLVI data on Trackinsight

More TMED data on Trackinsight

Exposure

Countries

XLVI

USA

96.67%

Other

3.33%

TMED

USA

85.53%

Other

14.47%

Sectors

XLVI

Health Care

97.69%

Other

2.31%

TMED

Health Care

87.36%

Other

12.64%

Diversification

XLVI

Total weight of top 15 holdings out of 15

70.39%

TMED

Total weight of top 15 holdings out of 15

53.6%

Top 15 holdings

Data as of April 30, 2026

XLVI

LILLY

13.98%

JOHNSON&JOHNSON

10.46%

ABBVIE

7.05%

UNITEDHEALTH GRP

6.34%

MERCK & CO INC

5.12%

AMGEN-T

3.52%

THERMO FISHER SCIENTIFIC

3.40%

INTUITIVE SURGICAL

3.07%

GILEAD SCIENCES

3.06%

ABBOTT LABS

2.98%

PFIZER

2.87%

BRISTOL-MYERS SQUIBB

2.33%

DANAHER

2.13%

VERTEX PHARMACEUTICALS

2.05%

STRYKER

2.05%

TMED

LILLY

14.29%

UNITEDHEALTH GRP

8.22%

GILEAD SCIENCES

4.61%

THERMO FISHER SCIENTIFIC

4.23%

ABBOTT LABS

3.82%

DANAHER

2.60%

STRYKER

2.08%

HUMANA

1.91%

DYNE THERAPEUTICS INC

1.79%

ALNYLAM PHARMACEUTICALS

1.75%

WEST PHARM SVCS

1.75%

BOSTON SCIENTIFIC

1.72%

WATERS

1.64%

AGILENT TECHNOLOGIES

1.63%

MEDTRONIC PLC

1.56%

Frequently asked questions about XLVI and TMED

XLVIvsTMEDETF Comparison

State Street Health Care Select Sector SPDR Premium Income Fund

T. Rowe Price Health Care ETF

XLVI vs TMED performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the XLVI and TMED ETFs performed in 2026?

As of June 9, 2026, XLVI is up 2.13% year-to-date (YTD), while TMED has returned 5.76%. That puts TMED better performer ahead so far this year.

Which ETF is attracting more investor money: XLVI or TMED?

Year-to-date, the XLVI ETF saw +$4M in flows, compared to +$3M for TMED.

Which ETF is bigger: XLVI or TMED?

As of June 9, 2026, XLVI holds $14.84 M in assets under management (AUM), while TMED manages $20.40 M.

What sectors do the XLVI and TMED ETFs invest in?

XLVI leans toward sectors like Health Care. Meanwhile, TMED focuses on Health Care.

What are the top holdings of the XLVI ETF and TMED ETF?

XLVI top holdings include LILLY, JOHNSON&JOHNSON and ABBVIE. TMED holds in its top three: LILLY, UNITEDHEALTH GRP and GILEAD SCIENCES.

Which ETF is more diversified: XLVI or TMED?

XLVI holds 58 securities with 70.39% of its assets in the top 15. TMED has 79 securities and a top 15 weight of 53.6%.

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