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XLVIvsPBPHETF Comparison

ETF 1
XLVI

State Street Health Care Select Sector SPDR Premium Income Fund

This fund is part of
Options Strategies
+0.4%
VS
ETF 2
PBPH

Portfolio Building Block World Pharma and Biotech Index ETF

This fund is part of
DM Large & Mid Cap
+1.12%

State Street Health Care Select Sector SPDR Premium Income Fund (XLVI) belongs to the Options Strategies segment. Portfolio Building Block World Pharma and Biotech Index ETF (PBPH) is part of the DM Large & Mid Cap segment. Both ETFs have the same top 3 sector exposures: and Health Care. XLVI is more expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.13% for PBPH. XLVI is up 2.27% year-to-date (YTD) with +$4M in YTD flows. PBPH performs better with 2.87% YTD performance, and +$830M in YTD flows. Run a side-by-side ETF comparison of XLVI and PBPH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XLVI vs PBPH performance and flow charts

Performance

-1.00.01.02.03.04.05.0%May 12May 19May 26Jun 2Jun 9

Cumulative Flows

0 M5 M10 M15 M20 M25 MMay 12May 19May 26Jun 2Jun 9

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Historic performance and flows
Data as of 06/12/2026
1M3MYTD1Y3Y5Y
Perf.
XLVI
PBPH
+4.57%+3.38%
+3.73%+1.37%
+2.27%+2.87%
n/an/a
n/an/a
n/an/a
Flows
XLVI
PBPH
+$2M+$25M
+$2M+$95M
+$4M+$830M
--
--
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
XLVI
PBPH
+13.13%+17.19%
n/an/a
n/an/a
n/an/a
Max drawdown
XLVI
PBPH
-4.28%-5.84%
n/an/a
n/an/a
n/an/a
Max drawdown duration
XLVI
PBPH
65d56d
n/an/a
n/an/a
n/an/a
Trading data

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XLVI
PBPH
Last sale
6/12/2026 at 1:30 PM
$25.64
$25.97
Previous close
06/11/2026
$25.60
$26.08
Consolidated volume
06/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of May 29, 2026
1-year trailing difference

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XLVI
is actively managed and doesn’t replicate an index

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XLVI
PBPH
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
XLVI
PBPH
Last price
$25.64
$25.97
1D performance
+0.14%
-0.44%
AuM$15.12 M$812.18 M
E/R0.35%0.13%
Characteristics
XLVI
PBPH
Management strategyActivePassive
ProviderState Street Investment ManagementTidal
Benchmark-BITA Global Pharma and Biotech Select Index
N° of holdings5549
Asset class--
Trailing 12m distribution yield
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Inception dateJuly 30, 2025November 24, 2025
ESGNoNo
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Exposure

Countries

XLVI
USA
96.67%
Other
3.33%
PBPH
USA
62.04%
Other
37.96%

Sectors

XLVI
Health Care
97.69%
Other
2.31%
PBPH
Health Care
88.29%
Other
11.71%
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Diversification

XLVI

Total weight of top 15 holdings out of 15

70.39%
PBPH

Total weight of top 15 holdings out of 15

67.47%

Top 15 holdings

Data as of April 30, 2026
XLVI
LILLY
13.98%
JOHNSON&JOHNSON
10.46%
ABBVIE
7.05%
UNITEDHEALTH GRP
6.34%
MERCK & CO INC
5.12%
AMGEN-T
3.52%
THERMO FISHER SCIENTIFIC
3.40%
INTUITIVE SURGICAL
3.07%
GILEAD SCIENCES
3.06%
ABBOTT LABS
2.98%
PFIZER
2.87%
BRISTOL-MYERS SQUIBB
2.33%
DANAHER
2.13%
VERTEX PHARMACEUTICALS
2.05%
STRYKER
2.05%
PBPH
LILLY
12.31%
JOHNSON&JOHNSON
9.12%
ABBVIE
5.86%
NOVARTIS
4.60%
MERCK & CO INC
4.57%
AMGEN-T
4.35%
GILEAD SCIENCES
4.23%
PFIZER
4.06%
NOVO-NORDISK
3.52%
BRISTOL-MYERS SQUIBB
3.13%
VERTEX PHARMACEUTICALS
2.88%
GSK PLC
2.73%
SANOFI SA
2.69%
REGENERON PHARMACEUTICALS
2.03%
CSL
1.39%
Frequently asked questions about XLVI and PBPH

How have the XLVI and PBPH ETFs performed in 2026?

As of June 12, 2026, XLVI is up 2.27% year-to-date (YTD), while PBPH has returned 2.87%. That puts PBPH better performer ahead so far this year.

Which ETF is attracting more investor money: XLVI or PBPH?

Year-to-date, the XLVI ETF saw +$4M in flows, compared to +$830M for PBPH.

Which ETF is bigger: XLVI or PBPH?

As of June 12, 2026, XLVI holds $15.12 M in assets under management (AUM), while PBPH manages $812.18 M.

What sectors do the XLVI and PBPH ETFs invest in?

XLVI leans toward sectors like Health Care. Meanwhile, PBPH focuses on Health Care.

What are the top holdings of the XLVI ETF and PBPH ETF?

XLVI top holdings include LILLY, JOHNSON&JOHNSON and ABBVIE. PBPH holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.

Which ETF is more diversified: XLVI or PBPH?

XLVI holds 58 securities with 70.39% of its assets in the top 15. PBPH has 49 securities and a top 15 weight of 67.47%.

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