XLVIvsIYHETF Comparison
ETF 1
XLVI
State Street Health Care Select Sector SPDR Premium Income Fund
This fund is part of
Options Strategies
-0.49%
VS
State Street Health Care Select Sector SPDR Premium Income Fund (XLVI) belongs to the Options Strategies segment. iShares U.S. Healthcare ETF (IYH) is part of the US Health Care segment. XLVI's top 2 sector exposures are Healthcare and Consumer Non-Cyclicals. In contrast, IYH's top sector exposures are Healthcare, Non-Corporate and Finance. XLVI is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.37% for IYH. XLVI is up 5.69% year-to-date (YTD) with +$14M in YTD flows. IYH performs better with 8.18% YTD performance, and -$211M in YTD flows. Run a side-by-side ETF comparison of XLVI and IYH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XLVI vs IYH performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/10/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XLVI IYH | -3.75%-1.60% | +3.97%+9.50% | +5.69%+8.18% | +16.54%+22.40% | n/a+29.64% | n/a+28.79% |
| Flows | XLVI IYH | +$4M-$116M | +$11M+$169M | +$14M-$211M | +$25M+$269M | --$303M | --$49M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XLVI IYH | +11.87%+19.35% | +11.09%+16.38% | n/a+14.97% | n/a+15.44% |
| Max drawdown | XLVI IYH | -4.77%-5.80% | -8.21%-10.72% | n/a-17.89% | n/a-17.89% |
| Max drawdown duration | XLVI IYH | 16d22d | 115d169d | n/a445d | n/a445d |
Trading data
XLVI | IYH | |
Last sale 9/11/2026 at 1:30 PM | $25.71 | $69.92 |
| Previous close 09/10/2026 | $25.73 | $70.00 |
| Consolidated volume 09/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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XLVI
is actively managed and doesn’t replicate an indexXLVI | IYH | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/11/2026 at 1:30 PM
Live
Closed
XLVI | IYH | |
|---|---|---|
| Last price | $25.71 | $69.92 |
| 1D performance | -0.07% | -0.11% |
| AuM | $25.47 M | $3.61 B |
| E/R | 0.35% | 0.37% |
Characteristics
XLVI | IYH | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | State Street Investment Management | iShares |
| Benchmark | - | Russell 1000 Health Care RIC 22.5/45 Capped Gross Index |
| N° of holdings | 59 | 101 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | July 30, 2025 | June 12, 2000 |
| ESG | No | No |
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Exposure
Countries
XLVI
USA
97.34%
Other
2.66%
IYH
USA
96.84%
Other
3.16%
Sectors
XLVI
Healthcare
97.32%
Other
2.68%
IYH
Healthcare
99.75%
Other
0.25%
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Diversification
XLVI
Total weight of top 15 holdings out of 15
71.63%
IYH
Total weight of top 15 holdings out of 15
69.24%
Top 15 holdings
Data as of July 31, 2026
XLVI
Eli Lilly & Co.
15.45%
Johnson & Johnson
10.49%
AbbVie, Inc.
7.54%
UnitedHealth Group, Inc.
6.40%
Merck & Co., Inc.
5.47%
Thermo Fisher Scientific, Inc.
3.63%
Amgen, Inc.
3.53%
Abbott Laboratories
3.13%
Gilead Sciences, Inc.
2.75%
Pfizer Inc.
2.42%
Bristol Myers Squibb Co.
2.27%
CVS Health Corp.
2.27%
Intuitive Surgical, Inc.
2.13%
Danaher Corp.
2.09%
Vertex Pharmaceuticals, Inc.
2.06%
IYH
Eli Lilly & Co.
15.09%
Johnson & Johnson
10.09%
AbbVie, Inc.
7.46%
UnitedHealth Group, Inc.
6.23%
Merck & Co., Inc.
5.25%
Thermo Fisher Scientific, Inc.
3.51%
Amgen, Inc.
3.42%
Abbott Laboratories
2.99%
Gilead Sciences, Inc.
2.67%
Pfizer Inc.
2.32%
Bristol Myers Squibb Co.
2.17%
Intuitive Surgical, Inc.
2.04%
Danaher Corp.
2.03%
Vertex Pharmaceuticals, Inc.
2.00%
Stryker Corp.
1.97%
Frequently asked questions about XLVI and IYH
How have the XLVI and IYH ETFs performed in 2026?
As of September 10, 2026, XLVI is up 5.69% year-to-date (YTD), while IYH has returned 8.18%. That puts IYH better performer ahead so far this year.
Which ETF is attracting more investor money: XLVI or IYH?
Year-to-date, the XLVI ETF saw +$14M in flows, compared to -$211M for IYH.
Which ETF is more volatile: XLVI or IYH?
Over the past year, XLVI had a volatility of 11.09%, while IYH experienced 16.38%.
Which ETF is bigger: XLVI or IYH?
As of September 10, 2026, XLVI holds $25.47 M in assets under management (AUM), while IYH manages $3.61 B.
What sectors do the XLVI and IYH ETFs invest in?
XLVI leans toward sectors like Healthcare. Meanwhile, IYH focuses on Healthcare.
What are the top holdings of the XLVI ETF and IYH ETF?
XLVI top holdings include Eli Lilly & Co., Johnson & Johnson and AbbVie, Inc.. IYH holds in its top three: Eli Lilly & Co., Johnson & Johnson and AbbVie, Inc..
Which ETF is more diversified: XLVI or IYH?
XLVI holds 59 securities with 71.63% of its assets in the top 15. IYH has 101 securities and a top 15 weight of 69.24%.
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Latest news about XLVI & IYH
Health Care Sector Down After a Cyberattack on UnitedHealth
March 4, 2024
IYH
Healthcare Stocks Rebound
August 14, 2023
IYH
Continued tightening of the U.S. labor market
September 23, 2022
IYH
U.S. labor market facing tight conditions
July 5, 2022
IYH
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