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XLVIvsBMEDETF Comparison

ETF 1

XLVI

State Street Health Care Select Sector SPDR Premium Income Fund

This fund is part of

Options Strategies

-0.17%

Full XLVI fund page

VS

ETF 2

BMED

iShares Health Innovation Active ETF

This fund is part of

Healthcare Technology

-0.26%

Full BMED fund page

State Street Health Care Select Sector SPDR Premium Income Fund (XLVI) belongs to the Options Strategies segment. iShares Health Innovation Active ETF (BMED) is part of the Healthcare Technology segment. XLVI's top 3 sector exposures are Healthcare and Consumer Non-Cyclicals. In contrast, BMED's top sector exposures are Healthcare and Non-Corporate. XLVI is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.77% for BMED. XLVI is up 5.2% year-to-date (YTD) with +$7M in YTD flows. BMED performs worse with 1.7% YTD performance, and +$4M in YTD flows. Run a side-by-side ETF comparison of XLVI and BMED below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XLVI vs BMED performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 07/22/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	XLVI BMED	+3.88%+4.43%	+7.81%+9.15%	+5.20%+1.70%	n/a+20.98%	n/a+25.40%	n/a+4.73%
Flows	XLVI BMED	+$2M-	+$5M-	+$7M+$4M	-+$6M	-+$4M	-+$5M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	XLVI BMED	+12.38%+17.47%	n/a+16.01%	n/a+16.05%	n/a+17.72%
Max drawdown	XLVI BMED	-2.06%-4.62%	n/a-14.71%	n/a-19.76%	n/a-33.96%
Max drawdown duration	XLVI BMED	7d19d	n/a183d	n/a237d	n/a1586d

Trading data

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	XLVI	BMED
Last sale 7/24/2026 at 1:30 PM	$26.52	$30.73
Previous close 07/23/2026	$26.33	$30.76
Consolidated volume 07/23/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Main metrics

Last update 7/24/2026 at 1:30 PM

Live

Closed

	XLVI	BMED
Last price	$26.52	$30.73
1D performance	+0.72%	-0.09%
AuM	$18.27 M	$11.06 M
E/R	0.35%	0.77%

Characteristics

	XLVI	BMED
Management strategy	Active	Active
Provider	State Street Investment Management	iShares
Benchmark	-	-
N° of holdings	59	52
Asset class	-	-
Trailing 12m distribution yield	Join	Join
Inception date	July 30, 2025	September 29, 2020
ESG	No	No

More XLVI data on Trackinsight

More BMED data on Trackinsight

Exposure

Countries

XLVI

USA

100.53%

Other

-0.53%

BMED

USA

88.93%

Other

11.07%

Sectors

XLVI

Healthcare

100.33%

Other

-0.33%

BMED

Healthcare

97.21%

Other

2.79%

Diversification

XLVI

Total weight of top 15 holdings out of 15

74.76%

BMED

Total weight of top 15 holdings out of 15

59.83%

Top 15 holdings

Data as of June 30, 2026

XLVI

Eli Lilly & Co.

17.01%

Johnson & Johnson

10.96%

AbbVie, Inc.

7.97%

UnitedHealth Group, Inc.

6.77%

Merck & Co., Inc.

5.69%

Amgen, Inc.

3.50%

Thermo Fisher Scientific, Inc.

3.34%

Abbott Laboratories

2.83%

Gilead Sciences, Inc.

2.81%

Intuitive Surgical, Inc.

2.53%

Pfizer Inc.

2.46%

CVS Health Corp.

2.37%

Vertex Pharmaceuticals, Inc.

2.26%

Danaher Corp.

2.15%

Bristol Myers Squibb Co.

2.11%

BMED

Merck & Co., Inc.

5.90%

Johnson & Johnson

5.13%

Gilead Sciences, Inc.

4.77%

Edwards Lifesciences Corp.

4.70%

BlackRock Cash Funds - Treasury

4.08%

Biogen, Inc.

3.79%

Moderna, Inc.

3.78%

Thermo Fisher Scientific, Inc.

3.69%

Charles River Laboratories International, Inc.

3.67%

Danaher Corp.

3.59%

Waters Corp.

3.52%

AbbVie, Inc.

3.49%

Amgen, Inc.

3.44%

Mettler-Toledo International, Inc.

3.17%

Vertex Pharmaceuticals, Inc.

3.11%

Frequently asked questions about XLVI and BMED

How have the XLVI and BMED ETFs performed in 2026?

As of July 22, 2026, XLVI is up 5.2% year-to-date (YTD), while BMED has returned 1.7%. That puts XLVI better performer ahead so far this year.

Which ETF is attracting more investor money: XLVI or BMED?

Year-to-date, the XLVI ETF saw +$7M in flows, compared to +$4M for BMED.

Which ETF is bigger: XLVI or BMED?

As of July 22, 2026, XLVI holds $18.27 M in assets under management (AUM), while BMED manages $11.06 M.

What sectors do the XLVI and BMED ETFs invest in?

XLVI leans toward sectors like Healthcare. Meanwhile, BMED focuses on Healthcare.

What are the top holdings of the XLVI ETF and BMED ETF?

XLVI top holdings include Eli Lilly & Co., Johnson & Johnson and AbbVie, Inc.. BMED holds in its top three: Merck & Co., Inc., Johnson & Johnson and Gilead Sciences, Inc..

XLVIvsBMEDETF Comparison

State Street Health Care Select Sector SPDR Premium Income Fund

iShares Health Innovation Active ETF

XLVI vs BMED performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the XLVI and BMED ETFs performed in 2026?

As of July 22, 2026, XLVI is up 5.2% year-to-date (YTD), while BMED has returned 1.7%. That puts XLVI better performer ahead so far this year.

Which ETF is attracting more investor money: XLVI or BMED?

Year-to-date, the XLVI ETF saw +$7M in flows, compared to +$4M for BMED.

Which ETF is bigger: XLVI or BMED?

As of July 22, 2026, XLVI holds $18.27 M in assets under management (AUM), while BMED manages $11.06 M.

What sectors do the XLVI and BMED ETFs invest in?

XLVI leans toward sectors like Healthcare. Meanwhile, BMED focuses on Healthcare.

What are the top holdings of the XLVI ETF and BMED ETF?

XLVI top holdings include Eli Lilly & Co., Johnson & Johnson and AbbVie, Inc.. BMED holds in its top three: Merck & Co., Inc., Johnson & Johnson and Gilead Sciences, Inc..

Which ETF is more diversified: XLVI or BMED?

XLVI holds 59 securities with 74.76% of its assets in the top 15. BMED has 55 securities and a top 15 weight of 59.83%.

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