XHSvsWDNAETF Comparison
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State Street SPDR S&P Health Care Services ETF (XHS) belongs to the US Health Care segment. WisdomTree BioRevolution Fund (WDNA) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. XHS is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.45% for WDNA. XHS is up 14.1% year-to-date (YTD) with +$13M in YTD flows. WDNA performs worse with 6.38% YTD performance, and -$357K in YTD flows. Run a side-by-side ETF comparison of XHS and WDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XHS vs WDNA performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 06/12/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHS WDNA | +7.30%+0.35% | +18.28%+4.10% | +14.10%+6.38% | +25.29%+41.07% | +34.73%+6.24% | +7.94%-27.71% |
| Flows | XHS WDNA | +$1M- | +$8M- | +$13M-$357K | +$79K-$357K | -$23M-$524K | -$74M+$2M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHS WDNA | +16.63%+24.10% | +17.99%+25.60% | +17.97%+24.90% | +21.22%+24.83% |
| Max drawdown | XHS WDNA | -5.61%-9.07% | -11.97%-11.90% | -17.78%-37.80% | -32.53%-58.58% |
| Max drawdown duration | XHS WDNA | 21d54d | 121d141d | 362d901d | 1786d1744d |
Trading data
XHS | WDNA | |
Last sale 6/12/2026 at 1:30 PM | $122.08 | $18.01 |
| Previous close 06/11/2026 | $121.70 | $18.02 |
| Consolidated volume 06/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of May 29, 2026
1-year trailing difference
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XHS | WDNA | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 6/12/2026 at 1:30 PM
Live
Closed
XHS | WDNA | |
|---|---|---|
| Last price | $122.08 | $18.01 |
| 1D performance | +0.31% | -0.08% |
| AuM | $109.72 M | $2.34 M |
| E/R | 0.35% | 0.45% |
Characteristics
XHS | WDNA | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | WisdomTree |
| Benchmark | S&P Health Care Services Select Industry Index | WisdomTree BioRevolution Index |
| N° of holdings | 51 | 72 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 28, 2011 | June 3, 2021 |
| ESG | No | No |
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Exposure
Countries
XHS
USA
99.91%
Other
0.09%
WDNA
USA
82.87%
Other
17.13%
Sectors
XHS
Health Care
86.95%
Other
13.05%
WDNA
Health Care
79.21%
Other
20.79%
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Diversification
XHS
Total weight of top 15 holdings out of 15
33.75%
WDNA
Total weight of top 15 holdings out of 15
39.77%
Top 15 holdings
Data as of April 30, 2026
XHS
CENTENE
2.76%
HUMANA
2.55%
MOLINA HLTHCRE
2.44%
ELEVANCE HEALTH INC
2.39%
UNITEDHEALTH GRP
2.39%
ALIGNMENT HEALTHCARE
2.31%
CLOVER HEALTH INV CORP
2.28%
APOLLO MEDICAL HOLDINGS INC
2.25%
US10950A1060
2.14%
MEDNAX
2.10%
PRIVIA HEALTH GROUP
2.07%
CIGNA
2.05%
CVS HEALTH CORP
2.03%
CORVEL
2.00%
ACADIA HEALTHCARE COMPANY
2.00%
WDNA
TWIST BIOSCIENCE CORP
3.90%
LILLY
3.44%
MODERNA INC
3.21%
JOHNSON&JOHNSON
3.16%
UTD THERAPEUT
3.07%
IMMUNOME
2.90%
DARLING INGREDIENTS INC
2.65%
STOKE THERAPEUTICS INC
2.46%
US88023B1035
2.34%
CORTEVA INC
2.22%
BEAM THERAPEUTICS
2.12%
ASTRAZENECA
2.12%
CH1300646267
2.12%
IONIS PHARMACEUTICALS INC
2.08%
NATERA
1.98%
Frequently asked questions about XHS and WDNA
How have the XHS and WDNA ETFs performed in 2026?
As of June 12, 2026, XHS is up 14.1% year-to-date (YTD), while WDNA has returned 6.38%. That puts XHS better performer ahead so far this year.
Which ETF is attracting more investor money: XHS or WDNA?
Year-to-date, the XHS ETF saw +$13M in flows, compared to -$357K for WDNA.
Which ETF is more volatile: XHS or WDNA?
Over the past year, XHS had a volatility of 17.99%, while WDNA experienced 25.6%.
Which ETF is bigger: XHS or WDNA?
As of June 12, 2026, XHS holds $109.72 M in assets under management (AUM), while WDNA manages $2.34 M.
What sectors do the XHS and WDNA ETFs invest in?
XHS leans toward sectors like Health Care. Meanwhile, WDNA focuses on Health Care.
What are the top holdings of the XHS ETF and WDNA ETF?
XHS top holdings include CENTENE, HUMANA and MOLINA HLTHCRE. WDNA holds in its top three: TWIST BIOSCIENCE CORP, LILLY and MODERNA INC.
Which ETF is more diversified: XHS or WDNA?
XHS holds 58 securities with 33.75% of its assets in the top 15. WDNA has 80 securities and a top 15 weight of 39.77%.
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