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XHSvsPBEETF Comparison

ETF 1

XHS

State Street SPDR S&P Health Care Services ETF

This fund is part of

US Health Care

-1.03%

Full XHS fund page

VS

ETF 2

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

+0.3%

Full PBE fund page

State Street SPDR S&P Health Care Services ETF (XHS) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. XHS's top 3 sector exposures are Healthcare, Consumer Non-Cyclicals and Business Services. In contrast, PBE's top sector exposures are Healthcare. XHS is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.59% for PBE. XHS is up 32.24% year-to-date (YTD) with +$103M in YTD flows. PBE performs worse with 21.44% YTD performance, and +$113M in YTD flows. Run a side-by-side ETF comparison of XHS and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XHS vs PBE performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 10/23/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	XHS PBE	+5.46%+2.54%	+7.08%+9.63%	+32.24%+21.44%	+35.98%+36.89%	+78.28%+84.49%	+36.44%+33.87%
Flows	XHS PBE	-$13M-$947K	+$3M+$111M	+$103M+$113M	+$107M+$115M	+$74M+$62M	+$37M+$65M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	XHS PBE	+17.05%+21.41%	+17.59%+19.97%	+18.30%+20.69%	+21.37%+22.69%
Max drawdown	XHS PBE	-5.21%-5.97%	-11.97%-11.70%	-14.46%-22.21%	-29.93%-32.63%
Max drawdown duration	XHS PBE	30d46d	121d166d	250d324d	1477d1468d

Trading data

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	XHS	PBE
Last sale 10/23/2026 at 1:30 PM	$141.40	$98.72
Previous close 10/22/2026	$142.69	$99.38
Consolidated volume 10/22/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of September 30, 2026

1-year trailing difference

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	XHS	PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 10/23/2026 at 1:30 PM

Live

Closed

	XHS	PBE
Last price	$141.40	$98.72
1D performance	-0.90%	-0.66%
AuM	$221.73 M	$429.04 M
E/R	0.35%	0.59%

Characteristics

	XHS	PBE
Management strategy	Passive	Passive
Provider	State Street Investment Management	Invesco
Benchmark	S&P Health Care Services Select Industry Index	Dynamic Biotech & Genome Intellidex Index
N° of holdings	59	30
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	September 28, 2011	June 23, 2005
ESG	No	No

More XHS data on Trackinsight

More PBE data on Trackinsight

Exposure

Countries

XHS

USA

99.94%

Other

0.06%

PBE

USA

97.22%

Other

2.78%

Sectors

XHS

Healthcare

95.16%

Other

4.84%

PBE

Healthcare

100%

Other

0%

Diversification

XHS

Total weight of top 15 holdings out of 15

33.1%

PBE

Total weight of top 15 holdings out of 15

63.67%

Top 15 holdings

Data as of August 31, 2026

XHS

Tenet Healthcare Corp.

2.65%

NeoGenomics, Inc.

2.60%

Lifestance Health Group, Inc.

2.58%

GeneDx Holdings Corp.

2.56%

Hinge Health, Inc.

2.45%

RadNet, Inc.

2.14%

Concentra Group Holdings Parent, Inc.

2.08%

Aveanna Healthcare Holdings, Inc.

2.07%

Labcorp Holdings, Inc.

2.03%

U.S. Physical Therapy, Inc.

2.03%

PACS Group, Inc.

2.02%

Addus HomeCare Corp.

2.02%

Guardant Health, Inc.

1.99%

Chemed Corp.

1.96%

Quest Diagnostics, Inc.

1.93%

PBE

CareDx, Inc.

5.49%

Amgen, Inc.

5.38%

Regeneron Pharmaceuticals, Inc.

5.26%

Vertex Pharmaceuticals, Inc.

5.21%

Royalty Pharma Plc

4.76%

Biogen, Inc.

4.75%

Gilead Sciences, Inc.

4.61%

United Therapeutics Corp.

3.77%

Omeros Corp.

3.73%

Repligen Corp.

3.57%

Illumina, Inc.

3.54%

Halozyme Therapeutics, Inc.

3.51%

Bio-Techne Corp.

3.41%

Protagonist Therapeutics, Inc.

3.37%

Alnylam Pharmaceuticals, Inc.

3.31%

Frequently asked questions about XHS and PBE

How have the XHS and PBE ETFs performed in 2026?

As of October 23, 2026, XHS is up 32.24% year-to-date (YTD), while PBE has returned 21.44%. That puts XHS better performer ahead so far this year.

Which ETF is attracting more investor money: XHS or PBE?

Year-to-date, the XHS ETF saw +$103M in flows, compared to +$113M for PBE.

Which ETF is more volatile: XHS or PBE?

Over the past year, XHS had a volatility of 17.59%, while PBE experienced 19.97%.

Which ETF is bigger: XHS or PBE?

As of October 23, 2026, XHS holds $221.73 M in assets under management (AUM), while PBE manages $429.04 M.

What sectors do the XHS and PBE ETFs invest in?

XHS leans toward sectors like Healthcare. Meanwhile, PBE focuses on Healthcare.

What are the top holdings of the XHS ETF and PBE ETF?

XHS top holdings include Tenet Healthcare Corp., NeoGenomics, Inc. and Lifestance Health Group, Inc.. PBE holds in its top three: CareDx, Inc., Amgen, Inc. and Regeneron Pharmaceuticals, Inc..

XHSvsPBEETF Comparison

State Street SPDR S&P Health Care Services ETF

Invesco Dynamic Biotechnology & Genome ETF

XHS vs PBE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the XHS and PBE ETFs performed in 2026?

As of October 23, 2026, XHS is up 32.24% year-to-date (YTD), while PBE has returned 21.44%. That puts XHS better performer ahead so far this year.

Which ETF is attracting more investor money: XHS or PBE?

Year-to-date, the XHS ETF saw +$103M in flows, compared to +$113M for PBE.

Which ETF is more volatile: XHS or PBE?

Over the past year, XHS had a volatility of 17.59%, while PBE experienced 19.97%.

Which ETF is bigger: XHS or PBE?

As of October 23, 2026, XHS holds $221.73 M in assets under management (AUM), while PBE manages $429.04 M.

What sectors do the XHS and PBE ETFs invest in?

XHS leans toward sectors like Healthcare. Meanwhile, PBE focuses on Healthcare.

What are the top holdings of the XHS ETF and PBE ETF?

XHS top holdings include Tenet Healthcare Corp., NeoGenomics, Inc. and Lifestance Health Group, Inc.. PBE holds in its top three: CareDx, Inc., Amgen, Inc. and Regeneron Pharmaceuticals, Inc..

Which ETF is more diversified: XHS or PBE?

XHS holds 59 securities with 33.1% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 63.67%.

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