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SPDR S&P Health Care Services ETF (XHS) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. XHS is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.58% for PBE. XHS is down -1.55% year-to-date (YTD) with +$6M in YTD flows. PBE performs worse with -3.89% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of XHS and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHS PBE | -0.71%-3.57% | -2.04%-1.26% | -1.55%-3.89% | +11.15%+20.46% | +26.55%+31.83% | +1.67%+10.46% |
| Flows | XHS PBE | -$8M-$3M | +$2M+$969K | +$6M+$135K | -$3M-$32M | -$36M-$56M | -$38M-$39M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHS PBE | +17.76%+18.21% | +19.20%+22.16% | +18.15%+20.15% | +21.13%+22.81% |
| Max drawdown | XHS PBE | -5.98%-9.23% | -12.54%-16.18% | -17.78%-22.21% | -32.53%-34.74% |
| Max drawdown duration | XHS PBE | 63d62d | 128d107d | 362d324d | 1716d1540d |
XHS | PBE | |
Last sale 3/11/2026 at 1:30 PM | $104.90 | $78.26 |
| Previous close 03/10/2026 | $105.14 | $78.82 |
| Consolidated volume 03/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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XHS | PBE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
XHS | PBE | |
|---|---|---|
| Last price | $104.90 | $78.26 |
| 1D performance | -0.23% | -0.71% |
| AuM | $87.35 M | $249.34 M |
| E/R | 0.35% | 0.58% |
XHS | PBE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | SPDR | Invesco |
| Benchmark | S&P Health Care Services Select Industry Index | Dynamic Biotech & Genome Intellidex Index |
| N° of holdings | 52 | 30 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 28, 2011 | June 23, 2005 |
| ESG | No | No |
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
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