XHSvsBBPETF Comparison
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State Street SPDR S&P Health Care Services ETF (XHS) belongs to the US Health Care segment. Virtus LifeSci Biotech Products ETF (BBP) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 3 sector exposures: and Health Care. XHS is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.79% for BBP. XHS is up 1.76% year-to-date (YTD) with +$9M in YTD flows. BBP performs better with 6.67% YTD performance, and +$12M in YTD flows. Run a side-by-side ETF comparison of XHS and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XHS vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHS BBP | +7.11%+5.15% | -2.43%+2.18% | +1.76%+6.67% | +14.80%+51.84% | +21.34%+65.27% | -0.83%+58.71% |
| Flows | XHS BBP | +$1M+$8M | -$5M+$12M | +$9M+$12M | -$3M+$27M | -$30M+$27M | -$34M+$17M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHS BBP | +18.84%+28.39% | +17.87%+24.04% | +18.09%+23.76% | +21.14%+26.19% |
| Max drawdown | XHS BBP | -11.77%-9.59% | -12.54%-9.81% | -17.78%-25.54% | -32.53%-38.24% |
| Max drawdown duration | XHS BBP | 88d48d | 128d36d | 362d292d | 1761d915d |
Trading data
XHS | BBP | |
Last sale 4/24/2026 at 7:59 PM | $108.86 | $84.11 |
| Previous close 04/24/2026 | $107.79 | $86.08 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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XHS | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/24/2026 at 7:59 PM
Live
Closed
XHS | BBP | |
|---|---|---|
| Last price | $108.86 | $84.11 |
| 1D performance | +0.99% | -2.30% |
| AuM | $93.51 M | $59.56 M |
| E/R | 0.35% | 0.79% |
Characteristics
XHS | BBP | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | VIRTUS Investment Partners |
| Benchmark | S&P Health Care Services Select Industry Index | LifeSci Biotechnology Products Index |
| N° of holdings | 51 | 56 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 28, 2011 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
XHS
USA
99.89%
Other
0.11%
BBP
USA
89.45%
Other
10.55%
Sectors
XHS
Health Care
86.56%
Other
13.44%
BBP
Health Care
88.78%
Other
11.22%
Diversification
XHS
Total weight of top 15 holdings out of 15
30.62%
BBP
Total weight of top 15 holdings out of 15
33.42%
Top 15 holdings
Data as of March 31, 2026
XHS
MEDNAX
2.18%
HEALTHEQUITY I/D
2.15%
GUARDANT HEALTH INC
2.12%
CORVEL
2.08%
US10950A1060
2.08%
CIGNA
2.06%
HUMANA
2.05%
ELEVANCE HEALTH INC
2.04%
DAVITA INC
2.00%
US5049221055
1.99%
ACADIA HEALTHCARE COMPANY
1.98%
CARDINAL HEALTH
1.98%
ALIGNMENT HEALTHCARE
1.98%
QUEST DIAGNOSTICS
1.97%
PROGYNY INC
1.96%
BBP
BIOCRYST PHARMACEUTICALS
2.50%
ROIVANT SCIENCES LTD
2.45%
SYNDAX PHARMACEUTICALS INC
2.40%
GILEAD SCIENCES
2.25%
GERON
2.24%
GB00BRXB0C07
2.23%
KALVISTA PHARMACEUTICALS INC
2.22%
AMGEN-T
2.20%
AXSOME THERA CMN STK
2.20%
AGIOS PHARMA/D
2.18%
BIOGEN INC
2.17%
UTD THERAPEUT
2.13%
LIGAND PHARMACEUTICALS
2.13%
BIOMARIN PHARMACEUTICAL
2.06%
EXELIXIS
2.05%
Frequently asked questions about XHS and BBP
How have the XHS and BBP ETFs performed in 2026?
As of April 24, 2026, XHS is up 1.76% year-to-date (YTD), while BBP has returned 6.67%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: XHS or BBP?
Year-to-date, the XHS ETF saw +$9M in flows, compared to +$12M for BBP.
Which ETF is more volatile: XHS or BBP?
Over the past year, XHS had a volatility of 17.87%, while BBP experienced 24.04%.
Which ETF is bigger: XHS or BBP?
As of April 24, 2026, XHS holds $93.51 M in assets under management (AUM), while BBP manages $59.56 M.
What sectors do the XHS and BBP ETFs invest in?
XHS leans toward sectors like Health Care. Meanwhile, BBP focuses on Health Care.
What are the top holdings of the XHS ETF and BBP ETF?
XHS top holdings include MEDNAX, HEALTHEQUITY I/D and GUARDANT HEALTH INC. BBP holds in its top three: BIOCRYST PHARMACEUTICALS, ROIVANT SCIENCES LTD and SYNDAX PHARMACEUTICALS INC.
Which ETF is more diversified: XHS or BBP?
XHS holds 58 securities with 30.62% of its assets in the top 15. BBP has 61 securities and a top 15 weight of 33.42%.
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