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XHEvsPBEETF Comparison

ETF 1

XHE

State Street SPDR S&P Health Care Equipment ETF

This fund is part of

US Health Care

-1.08%

Full XHE fund page

VS

ETF 2

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

-0.67%

Full PBE fund page

State Street SPDR S&P Health Care Equipment ETF (XHE) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. XHE is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.58% for PBE. XHE is down -6.1% year-to-date (YTD) with -$6M in YTD flows. PBE performs better with -2.66% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of XHE and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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XHE vs PBE performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	XHE PBE	+4.44%+4.27%	-6.33%-3.98%	-6.10%-2.66%	+4.10%+32.11%	-16.38%+28.24%	-34.81%+3.38%
Flows	XHE PBE	+$345K+$2M	-$4M-$6M	-$6M-$2M	-$35M-$30M	-$282M-$58M	-$404M-$43M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	XHE PBE	+23.06%+19.57%	+21.27%+19.83%	+21.32%+20.15%	+24.31%+22.54%
Max drawdown	XHE PBE	-14.31%-9.36%	-18.20%-11.70%	-32.60%-22.21%	-49.90%-34.74%
Max drawdown duration	XHE PBE	57d75d	106d107d	1096d324d	1695d1540d

Trading data

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	XHE	PBE
Last sale 4/27/2026 at 1:30 PM	$82.67	$79.93
Previous close 04/24/2026	$82.71	$79.82
Consolidated volume 04/24/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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	XHE	PBE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/27/2026 at 1:30 PM

Live

Closed

	XHE	PBE
Last price	$82.67	$79.93
1D performance	-0.05%	+0.14%
AuM	$138.61 M	$249.88 M
E/R	0.35%	0.58%

Characteristics

	XHE	PBE
Management strategy	Passive	Passive
Provider	State Street Investment Management	Invesco
Benchmark	S&P Health Care Equipment Select Industry Index	Dynamic Biotech & Genome Intellidex Index
N° of holdings	61	30
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	January 26, 2011	June 23, 2005
ESG	No	No

More XHE data on Trackinsight

More PBE data on Trackinsight

Exposure

Countries

XHE

USA

92.19%

Other

7.81%

PBE

USA

92.18%

Other

7.82%

Sectors

XHE

Health Care

89.87%

Other

10.13%

PBE

Health Care

97.59%

Other

2.41%

Diversification

XHE

Total weight of top 15 holdings out of 15

26.74%

PBE

Total weight of top 15 holdings out of 15

63.66%

Top 15 holdings

Data as of March 31, 2026

XHE

TELEFLEX

1.86%

STAAR SURGICAL

1.84%

BUTTERFLY NETWORK INC

1.84%

US58507V1070

1.83%

GLAUKOS

1.82%

INTEGER HOLDINGS

1.79%

AXOGEN

1.79%

LIVANOVA

1.78%

MASIMO

1.76%

LEMAITRE VASCULAR

1.75%

ARTIVION INC

1.75%

HOLOGIC

1.74%

STERIS

1.74%

GLOBUS MEDICAL

1.72%

IRHYTHM TECHNOLOGIES

1.72%

PBE

UTD THERAPEUT

6.05%

ILLUMINA

5.24%

REGENERON PHARMACEUTICALS

5.23%

ALNYLAM PHARMACEUTICALS

5.22%

BIOGEN INC

5.16%

AMGEN-T

4.99%

GILEAD SCIENCES

4.98%

INCYTE

4.89%

BIOCRYST PHARMACEUTICALS

3.66%

PROTAGONIST THERAPEUTICS INC

3.38%

TG THERAPEUTICS

3.11%

ROYALTY PHARMA

3.05%

NEUROCRINE BIOSCIENCES

2.93%

CATALYST PHARMACEUTICALS INC

2.89%

PTC THERAPEUTI/D

2.86%

Frequently asked questions about XHE and PBE

How have the XHE and PBE ETFs performed in 2026?

As of April 24, 2026, XHE is down -6.1% year-to-date (YTD), while PBE has lost -2.66%. That puts PBE better performer ahead so far this year.

Which ETF is attracting more investor money: XHE or PBE?

Year-to-date, the XHE ETF saw -$6M in flows, compared to -$2M for PBE.

Which ETF is more volatile: XHE or PBE?

Over the past year, XHE had a volatility of 21.27%, while PBE experienced 19.83%.

Which ETF is bigger: XHE or PBE?

As of April 24, 2026, XHE holds $138.61 M in assets under management (AUM), while PBE manages $249.88 M.

What sectors do the XHE and PBE ETFs invest in?

XHE leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the XHE ETF and PBE ETF?

XHE top holdings include TELEFLEX, STAAR SURGICAL and BUTTERFLY NETWORK INC. PBE holds in its top three: UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS.

XHEvsPBEETF Comparison

State Street SPDR S&P Health Care Equipment ETF

Invesco Dynamic Biotechnology & Genome ETF

XHE vs PBE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the XHE and PBE ETFs performed in 2026?

As of April 24, 2026, XHE is down -6.1% year-to-date (YTD), while PBE has lost -2.66%. That puts PBE better performer ahead so far this year.

Which ETF is attracting more investor money: XHE or PBE?

Year-to-date, the XHE ETF saw -$6M in flows, compared to -$2M for PBE.

Which ETF is more volatile: XHE or PBE?

Over the past year, XHE had a volatility of 21.27%, while PBE experienced 19.83%.

Which ETF is bigger: XHE or PBE?

As of April 24, 2026, XHE holds $138.61 M in assets under management (AUM), while PBE manages $249.88 M.

What sectors do the XHE and PBE ETFs invest in?

XHE leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.

What are the top holdings of the XHE ETF and PBE ETF?

XHE top holdings include TELEFLEX, STAAR SURGICAL and BUTTERFLY NETWORK INC. PBE holds in its top three: UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS.

Which ETF is more diversified: XHE or PBE?

XHE holds 67 securities with 26.74% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 63.66%.

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