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XHEvsPBEETF Comparison
SPDR S&P Health Care Equipment ETF (XHE) belongs to the US Health Care segment. Invesco Dynamic Biotechnology & Genome ETF (PBE) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. XHE is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.58% for PBE. XHE is down -7.18% year-to-date (YTD) with -$4M in YTD flows. PBE performs better with -3.89% YTD performance, and +$135K in YTD flows. Run a side-by-side ETF comparison of XHE and PBE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
XHE vs PBE performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHE PBE | -5.57%-3.57% | -8.58%-1.26% | -7.18%-3.89% | -2.13%+20.46% | -6.66%+31.83% | -30.59%+10.46% |
| Flows | XHE PBE | --$3M | -$4M+$969K | -$4M+$135K | -$44M-$32M | -$295M-$56M | -$430M-$39M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHE PBE | +18.92%+18.21% | +23.53%+22.16% | +21.08%+20.15% | +24.18%+22.81% |
| Max drawdown | XHE PBE | -12.38%-9.23% | -14.34%-16.18% | -32.63%-22.21% | -49.90%-34.74% |
| Max drawdown duration | XHE PBE | 61d62d | 241d107d | 1052d324d | 1650d1540d |
XHE | PBE | |
Last sale 3/11/2026 at 1:30 PM | $82.04 | $78.26 |
| Previous close 03/10/2026 | $81.73 | $78.82 |
| Consolidated volume 03/10/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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XHE | PBE | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
XHE | PBE | |
|---|---|---|
| Last price | $82.04 | $78.26 |
| 1D performance | +0.38% | -0.71% |
| AuM | $139.06 M | $249.34 M |
| E/R | 0.35% | 0.58% |
XHE | PBE | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | SPDR | Invesco |
| Benchmark | S&P Health Care Equipment Select Industry Index | Dynamic Biotech & Genome Intellidex Index |
| N° of holdings | 61 | 30 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 26, 2011 | June 23, 2005 |
| ESG | No | No |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the XHE and PBE ETFs performed in 2026?
As of March 10, 2026, XHE is down -7.18% year-to-date (YTD), while PBE has lost -3.89%. That puts PBE better performer ahead so far this year.
Which ETF is attracting more investor money: XHE or PBE?
Year-to-date, the XHE ETF saw -$4M in flows, compared to +$135K for PBE.
Which ETF is more volatile: XHE or PBE?
Over the past year, XHE had a volatility of 23.53%, while PBE experienced 22.16%.
Which ETF is bigger: XHE or PBE?
As of March 10, 2026, XHE holds $139.06 M in assets under management (AUM), while PBE manages $249.34 M.
What sectors do the XHE and PBE ETFs invest in?
XHE leans toward sectors like Health Care. Meanwhile, PBE focuses on Health Care.
What are the top holdings of the XHE ETF and PBE ETF?
XHE top holdings include NEOGEN, INTEGER HOLDINGS and PENUMBRA. PBE holds in its top three: ILLUMINA, GILEAD SCIENCES and AMGEN-T.
Which ETF is more diversified: XHE or PBE?
XHE holds 64 securities with 30.47% of its assets in the top 15. PBE has 30 securities and a top 15 weight of 61.48%.
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