XHEvsIBBQETF Comparison
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State Street SPDR S&P Health Care Equipment ETF (XHE) and Invesco Nasdaq Biotechnology ETF (IBBQ) belong to the same industry segment: US Health Care. XHE's top 2 sector exposures are Healthcare and Finance. In contrast, IBBQ's top sector exposures are Healthcare and Non-Energy Materials. XHE is more expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.19% for IBBQ. XHE is up 5.71% year-to-date (YTD) with -$9M in YTD flows. IBBQ performs better with 25.64% YTD performance, and +$38M in YTD flows. Run a side-by-side ETF comparison of XHE and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XHE vs IBBQ performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHE IBBQ | +1.69%+0.32% | +6.51%+9.87% | +5.71%+25.64% | +13.97%+36.17% | +39.19%+100.45% | -24.85%+50.62% |
| Flows | XHE IBBQ | -$40M+$14M | -$10M+$35M | -$9M+$38M | -$12M+$55M | -$223M+$74M | -$399M+$52M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHE IBBQ | +20.36%+25.72% | +22.70%+22.50% | +21.88%+21.20% | +24.86%+22.22% |
| Max drawdown | XHE IBBQ | -9.09%-8.58% | -18.20%-8.58% | -24.35%-23.78% | -49.37%-34.86% |
| Max drawdown duration | XHE IBBQ | 69d69d | 207d69d | 565d375d | 1819d1429d |
Trading data
XHE | IBBQ | |
Last sale 10/27/2026 at 1:30 PM | $93.25 | $35.38 |
| Previous close 10/27/2026 | $93.09 | $34.68 |
| Consolidated volume 10/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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XHE | IBBQ | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/27/2026 at 1:30 PM
Live
Closed
XHE | IBBQ | |
|---|---|---|
| Last price | $93.25 | $35.38 |
| 1D performance | +0.17% | +2.01% |
| AuM | $153.71 M | $117.67 M |
| E/R | 0.35% | 0.19% |
Characteristics
XHE | IBBQ | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | Invesco |
| Benchmark | S&P Health Care Equipment Select Industry Index | NASDAQ Biotechnology Index |
| N° of holdings | 67 | 249 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 26, 2011 | June 9, 2021 |
| ESG | No | No |
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Exposure
Countries
XHE
USA
93.57%
Other
6.43%
IBBQ
USA
88.22%
Other
11.78%
Sectors
XHE
Healthcare
97.47%
Other
2.53%
IBBQ
Healthcare
99.99%
Other
0.01%
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Diversification
XHE
Total weight of top 15 holdings out of 15
30.96%
IBBQ
Total weight of top 15 holdings out of 15
52.06%
Top 15 holdings
Data as of August 31, 2026
XHE
AtriCure, Inc.
2.59%
Strive, Inc. (United States)
2.47%
Inspire Medical Systems, Inc.
2.19%
Glaukos Corp.
2.16%
Butterfly Network, Inc.
2.15%
CONMED Corp.
2.02%
Integer Holdings Corp.
2.02%
Tandem Diabetes Care, Inc.
2.00%
Merit Medical Systems, Inc.
1.99%
Artivion, Inc.
1.94%
Haemonetics Corp.
1.93%
UFP Technologies, Inc.
1.89%
Baxter International, Inc.
1.88%
Becton, Dickinson & Co.
1.87%
Neogen Corp.
1.86%
IBBQ
Amgen, Inc.
8.60%
Vertex Pharmaceuticals, Inc.
8.10%
Gilead Sciences, Inc.
7.34%
Regeneron Pharmaceuticals, Inc.
5.26%
Moderna, Inc.
3.58%
Revolution Medicines, Inc.
2.97%
Illumina, Inc.
2.18%
Biogen, Inc.
2.07%
Alnylam Pharmaceuticals, Inc.
2.00%
argenx SE
1.84%
Royalty Pharma Plc
1.73%
Roivant Sciences Ltd.
1.71%
Insmed, Inc.
1.66%
Incyte Corp.
1.61%
United Therapeutics Corp.
1.42%
Frequently asked questions about XHE and IBBQ
How have the XHE and IBBQ ETFs performed in 2026?
As of October 27, 2026, XHE is up 5.71% year-to-date (YTD), while IBBQ has returned 25.64%. That puts IBBQ better performer ahead so far this year.
Which ETF is attracting more investor money: XHE or IBBQ?
Year-to-date, the XHE ETF saw -$9M in flows, compared to +$38M for IBBQ.
Which ETF is more volatile: XHE or IBBQ?
Over the past year, XHE had a volatility of 22.7%, while IBBQ experienced 22.5%.
Which ETF is bigger: XHE or IBBQ?
As of October 27, 2026, XHE holds $153.71 M in assets under management (AUM), while IBBQ manages $117.67 M.
What sectors do the XHE and IBBQ ETFs invest in?
XHE leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.
What are the top holdings of the XHE ETF and IBBQ ETF?
XHE top holdings include AtriCure, Inc., Strive, Inc. (United States) and Inspire Medical Systems, Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: XHE or IBBQ?
XHE holds 67 securities with 30.96% of its assets in the top 15. IBBQ has 249 securities and a top 15 weight of 52.06%.
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