XHEvsIBBQETF Comparison
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State Street SPDR S&P Health Care Equipment ETF (XHE) and Invesco Nasdaq Biotechnology ETF (IBBQ) belong to the same industry segment: US Health Care. XHE's top 2 sector exposures are Healthcare and Finance. In contrast, IBBQ's top sector exposures are Healthcare and Non-Energy Materials. XHE is more expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.19% for IBBQ. XHE is up 3.73% year-to-date (YTD) with +$13M in YTD flows. IBBQ performs better with 23.27% YTD performance, and +$19M in YTD flows. Run a side-by-side ETF comparison of XHE and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XHE vs IBBQ performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/09/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHE IBBQ | -3.04%+2.35% | +10.11%+19.52% | +3.73%+23.27% | +10.83%+46.13% | +9.19%+74.55% | -30.39%+34.66% |
| Flows | XHE IBBQ | +$5M+$15M | +$14M+$18M | +$13M+$19M | +$2M+$38M | -$264M+$54M | -$380M+$28M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHE IBBQ | +24.07%+24.31% | +22.81%+21.65% | +22.21%+20.89% | +24.83%+22.08% |
| Max drawdown | XHE IBBQ | -5.67%-6.21% | -18.20%-8.38% | -24.35%-23.78% | -49.37%-37.23% |
| Max drawdown duration | XHE IBBQ | 21d31d | 207d48d | 565d375d | 1771d1485d |
Trading data
XHE | IBBQ | |
Last sale 9/10/2026 at 1:30 PM | $89.53 | $34.41 |
| Previous close 09/09/2026 | $91.41 | $34.93 |
| Consolidated volume 09/09/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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XHE | IBBQ | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/10/2026 at 1:30 PM
Live
Closed
XHE | IBBQ | |
|---|---|---|
| Last price | $89.53 | $34.41 |
| 1D performance | -2.06% | -1.48% |
| AuM | $173.68 M | $97.02 M |
| E/R | 0.35% | 0.19% |
Characteristics
XHE | IBBQ | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | Invesco |
| Benchmark | S&P Health Care Equipment Select Industry Index | NASDAQ Biotechnology Index |
| N° of holdings | 66 | 249 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 26, 2011 | June 9, 2021 |
| ESG | No | No |
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Exposure
Countries
XHE
USA
93.56%
Other
6.44%
IBBQ
USA
88.05%
Other
11.95%
Sectors
XHE
Healthcare
98.72%
Other
1.28%
IBBQ
Healthcare
99.91%
Other
0.09%
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Diversification
XHE
Total weight of top 15 holdings out of 15
30.19%
IBBQ
Total weight of top 15 holdings out of 15
50.47%
Top 15 holdings
Data as of July 31, 2026
XHE
AtriCure, Inc.
2.14%
Glaukos Corp.
2.13%
Dentsply Sirona, Inc.
2.08%
Enovis Corp.
2.07%
Integer Holdings Corp.
2.07%
Butterfly Network, Inc.
2.06%
Neogen Corp.
2.05%
Artivion, Inc.
2.05%
Baxter International, Inc.
2.01%
CONMED Corp.
1.99%
Merit Medical Systems, Inc.
1.98%
QuidelOrtho Corp.
1.94%
ICU Medical, Inc.
1.88%
Tandem Diabetes Care, Inc.
1.88%
Inspire Medical Systems, Inc.
1.85%
IBBQ
Amgen, Inc.
8.55%
Vertex Pharmaceuticals, Inc.
8.03%
Gilead Sciences, Inc.
7.34%
Regeneron Pharmaceuticals, Inc.
5.08%
Revolution Medicines, Inc.
2.73%
Alnylam Pharmaceuticals, Inc.
2.71%
Biogen, Inc.
2.19%
Illumina, Inc.
2.09%
Royalty Pharma Plc
1.86%
Incyte Corp.
1.80%
argenx SE
1.73%
Roivant Sciences Ltd.
1.68%
Insmed, Inc.
1.58%
United Therapeutics Corp.
1.58%
Moderna, Inc.
1.53%
Frequently asked questions about XHE and IBBQ
How have the XHE and IBBQ ETFs performed in 2026?
As of September 9, 2026, XHE is up 3.73% year-to-date (YTD), while IBBQ has returned 23.27%. That puts IBBQ better performer ahead so far this year.
Which ETF is attracting more investor money: XHE or IBBQ?
Year-to-date, the XHE ETF saw +$13M in flows, compared to +$19M for IBBQ.
Which ETF is more volatile: XHE or IBBQ?
Over the past year, XHE had a volatility of 22.81%, while IBBQ experienced 21.65%.
Which ETF is bigger: XHE or IBBQ?
As of September 9, 2026, XHE holds $173.68 M in assets under management (AUM), while IBBQ manages $97.02 M.
What sectors do the XHE and IBBQ ETFs invest in?
XHE leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.
What are the top holdings of the XHE ETF and IBBQ ETF?
XHE top holdings include AtriCure, Inc., Glaukos Corp. and Dentsply Sirona, Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: XHE or IBBQ?
XHE holds 66 securities with 30.19% of its assets in the top 15. IBBQ has 249 securities and a top 15 weight of 50.47%.
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