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XHEvsGNOMETF Comparison
SPDR S&P Health Care Equipment ETF (XHE) belongs to the US Health Care segment. Global X Genomics & Biotechnology ETF - USD (GNOM) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. XHE is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.5% for GNOM. XHE is down -6.79% year-to-date (YTD) with -$4M in YTD flows. GNOM performs better with -0.99% YTD performance, and -$2M in YTD flows. Run a side-by-side ETF comparison of XHE and GNOM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
XHE vs GNOM performance and flow charts
Performance
Cumulative Flows
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHE GNOM | -4.63%-2.35% | -8.38%-3.29% | -6.79%-0.99% | -1.88%+29.80% | -7.27%-6.02% | -31.62%-51.80% |
| Flows | XHE GNOM | -- | -$7M-$4M | -$4M-$2M | -$44M-$19M | -$295M-$115M | -$430M+$11M |
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHE GNOM | +18.94%+23.45% | +23.53%+30.08% | +21.07%+28.53% | +24.17%+33.47% |
| Max drawdown | XHE GNOM | -12.38%-10.89% | -14.34%-22.14% | -32.63%-46.50% | -49.90%-72.17% |
| Max drawdown duration | XHE GNOM | 62d48d | 241d113d | 1053d1031d | 1651d1714d |
XHE | GNOM | |
Last sale 3/12/2026 at 1:30 PM | $79.80 | $43.93 |
| Previous close 03/11/2026 | $82.04 | $45.00 |
| Consolidated volume 03/11/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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XHE | GNOM | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
XHE | GNOM | |
|---|---|---|
| Last price | $79.80 | $43.93 |
| 1D performance | -2.73% | -2.38% |
| AuM | $139.64 M | $49.36 M |
| E/R | 0.35% | 0.5% |
Countries
Sectors
Diversification
Total weight of top 15 holdings out of 15
Total weight of top 15 holdings out of 15
Top 15 holdings
How have the XHE and GNOM ETFs performed in 2026?
As of March 11, 2026, XHE is down -6.79% year-to-date (YTD), while GNOM has lost -0.99%. That puts GNOM better performer ahead so far this year.
Which ETF is attracting more investor money: XHE or GNOM?
Year-to-date, the XHE ETF saw -$4M in flows, compared to -$2M for GNOM.
Which ETF is more volatile: XHE or GNOM?
Over the past year, XHE had a volatility of 23.53%, while GNOM experienced 30.08%.
Which ETF is bigger: XHE or GNOM?
As of March 11, 2026, XHE holds $139.64 M in assets under management (AUM), while GNOM manages $49.36 M.
What sectors do the XHE and GNOM ETFs invest in?
XHE leans toward sectors like Health Care. Meanwhile, GNOM focuses on Health Care.
What are the top holdings of the XHE ETF and GNOM ETF?
XHE top holdings include NEOGEN, INTEGER HOLDINGS and PENUMBRA. GNOM holds in its top three: MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070.
Which ETF is more diversified: XHE or GNOM?
XHE holds 64 securities with 30.47% of its assets in the top 15. GNOM has 48 securities and a top 15 weight of 63.95%.
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