XHEvsBBPETF Comparison
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State Street SPDR S&P Health Care Equipment ETF (XHE) belongs to the US Health Care segment. Virtus LifeSci Biotech Products ETF (BBP) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 3 sector exposures: and Health Care. XHE is less expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.79% for BBP. XHE is down -6.1% year-to-date (YTD) with -$6M in YTD flows. BBP performs better with 6.67% YTD performance, and +$12M in YTD flows. Run a side-by-side ETF comparison of XHE and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XHE vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHE BBP | +4.44%+5.15% | -6.33%+2.18% | -6.10%+6.67% | +4.10%+51.84% | -16.38%+65.27% | -34.81%+58.71% |
| Flows | XHE BBP | +$345K+$8M | -$4M+$12M | -$6M+$12M | -$35M+$27M | -$282M+$27M | -$404M+$17M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHE BBP | +23.06%+28.39% | +21.27%+24.04% | +21.32%+23.76% | +24.31%+26.19% |
| Max drawdown | XHE BBP | -14.31%-9.59% | -18.20%-9.81% | -32.60%-25.54% | -49.90%-38.24% |
| Max drawdown duration | XHE BBP | 57d48d | 106d36d | 1096d292d | 1695d915d |
Trading data
XHE | BBP | |
Last sale 4/27/2026 at 1:30 PM | $82.67 | $83.62 |
| Previous close 04/24/2026 | $82.71 | $84.11 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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XHE | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
XHE | BBP | |
|---|---|---|
| Last price | $82.67 | $83.62 |
| 1D performance | -0.05% | -0.57% |
| AuM | $138.61 M | $59.56 M |
| E/R | 0.35% | 0.79% |
Characteristics
XHE | BBP | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | VIRTUS Investment Partners |
| Benchmark | S&P Health Care Equipment Select Industry Index | LifeSci Biotechnology Products Index |
| N° of holdings | 61 | 56 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 26, 2011 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
XHE
USA
92.19%
Other
7.81%
BBP
USA
89.45%
Other
10.55%
Sectors
XHE
Health Care
89.87%
Other
10.13%
BBP
Health Care
88.78%
Other
11.22%
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Diversification
XHE
Total weight of top 15 holdings out of 15
26.74%
BBP
Total weight of top 15 holdings out of 15
33.42%
Top 15 holdings
Data as of March 31, 2026
XHE
TELEFLEX
1.86%
STAAR SURGICAL
1.84%
BUTTERFLY NETWORK INC
1.84%
US58507V1070
1.83%
GLAUKOS
1.82%
INTEGER HOLDINGS
1.79%
AXOGEN
1.79%
LIVANOVA
1.78%
MASIMO
1.76%
LEMAITRE VASCULAR
1.75%
ARTIVION INC
1.75%
HOLOGIC
1.74%
STERIS
1.74%
GLOBUS MEDICAL
1.72%
IRHYTHM TECHNOLOGIES
1.72%
BBP
BIOCRYST PHARMACEUTICALS
2.50%
ROIVANT SCIENCES LTD
2.45%
SYNDAX PHARMACEUTICALS INC
2.40%
GILEAD SCIENCES
2.25%
GERON
2.24%
GB00BRXB0C07
2.23%
KALVISTA PHARMACEUTICALS INC
2.22%
AMGEN-T
2.20%
AXSOME THERA CMN STK
2.20%
AGIOS PHARMA/D
2.18%
BIOGEN INC
2.17%
UTD THERAPEUT
2.13%
LIGAND PHARMACEUTICALS
2.13%
BIOMARIN PHARMACEUTICAL
2.06%
EXELIXIS
2.05%
Frequently asked questions about XHE and BBP
How have the XHE and BBP ETFs performed in 2026?
As of April 24, 2026, XHE is down -6.1% year-to-date (YTD), while BBP has returned 6.67%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: XHE or BBP?
Year-to-date, the XHE ETF saw -$6M in flows, compared to +$12M for BBP.
Which ETF is more volatile: XHE or BBP?
Over the past year, XHE had a volatility of 21.27%, while BBP experienced 24.04%.
Which ETF is bigger: XHE or BBP?
As of April 24, 2026, XHE holds $138.61 M in assets under management (AUM), while BBP manages $59.56 M.
What sectors do the XHE and BBP ETFs invest in?
XHE leans toward sectors like Health Care. Meanwhile, BBP focuses on Health Care.
What are the top holdings of the XHE ETF and BBP ETF?
XHE top holdings include TELEFLEX, STAAR SURGICAL and BUTTERFLY NETWORK INC. BBP holds in its top three: BIOCRYST PHARMACEUTICALS, ROIVANT SCIENCES LTD and SYNDAX PHARMACEUTICALS INC.
Which ETF is more diversified: XHE or BBP?
XHE holds 67 securities with 26.74% of its assets in the top 15. BBP has 61 securities and a top 15 weight of 33.42%.
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