XHEvsBBPETF Comparison
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State Street SPDR S&P Health Care Equipment ETF (XHE) belongs to the US Health Care segment. Virtus LifeSci Biotech Products ETF (BBP) is part of the Tomorrow's Treatments segment. XHE's top 2 sector exposures are Healthcare and Finance. In contrast, BBP's top sector exposures are Healthcare. XHE is more expensive with a Total Expense Ratio (TER) of 0.35%, versus 0.34% for BBP. XHE is up 3.73% year-to-date (YTD) with +$13M in YTD flows. BBP performs better with 32.02% YTD performance, and +$50M in YTD flows. Run a side-by-side ETF comparison of XHE and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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XHE vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/09/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | XHE BBP | -3.04%+4.09% | +10.11%+23.23% | +3.73%+32.02% | +10.83%+49.71% | +9.19%+98.63% | -30.39%+100.65% |
| Flows | XHE BBP | +$5M+$5M | +$14M+$20M | +$13M+$50M | +$2M+$62M | -$264M+$68M | -$380M+$61M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | XHE BBP | +24.07%+25.85% | +22.81%+25.14% | +22.21%+24.72% | +24.83%+26.61% |
| Max drawdown | XHE BBP | -5.67%-9.34% | -18.20%-9.59% | -24.35%-25.54% | -49.37%-37.61% |
| Max drawdown duration | XHE BBP | 21d39d | 207d48d | 565d292d | 1771d586d |
Trading data
XHE | BBP | |
Last sale 9/10/2026 at 1:30 PM | $89.53 | $103.47 |
| Previous close 09/09/2026 | $91.41 | $105.52 |
| Consolidated volume 09/09/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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XHE | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/10/2026 at 1:30 PM
Live
Closed
XHE | BBP | |
|---|---|---|
| Last price | $89.53 | $103.47 |
| 1D performance | -2.06% | -1.94% |
| AuM | $173.68 M | $115.83 M |
| E/R | 0.35% | 0.34% |
Characteristics
XHE | BBP | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | State Street Investment Management | VIRTUS Investment Partners |
| Benchmark | S&P Health Care Equipment Select Industry Index | LifeSci Biotechnology Products Index |
| N° of holdings | 66 | 66 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | January 26, 2011 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
XHE
USA
93.56%
Other
6.44%
BBP
USA
86.5%
Other
13.5%
Sectors
XHE
Healthcare
98.72%
Other
1.28%
BBP
Healthcare
98.2%
Other
1.8%
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Diversification
XHE
Total weight of top 15 holdings out of 15
30.19%
BBP
Total weight of top 15 holdings out of 15
26.78%
Top 15 holdings
Data as of July 31, 2026
XHE
AtriCure, Inc.
2.14%
Glaukos Corp.
2.13%
Dentsply Sirona, Inc.
2.08%
Enovis Corp.
2.07%
Integer Holdings Corp.
2.07%
Butterfly Network, Inc.
2.06%
Neogen Corp.
2.05%
Artivion, Inc.
2.05%
Baxter International, Inc.
2.01%
CONMED Corp.
1.99%
Merit Medical Systems, Inc.
1.98%
QuidelOrtho Corp.
1.94%
ICU Medical, Inc.
1.88%
Tandem Diabetes Care, Inc.
1.88%
Inspire Medical Systems, Inc.
1.85%
BBP
Crinetics Pharmaceuticals, Inc.
3.24%
Verastem, Inc.
1.98%
Nuvation Bio, Inc.
1.80%
Omeros Corp.
1.73%
Geron Corp.
1.72%
BridgeBio Pharma, Inc.
1.68%
Agios Pharmaceuticals, Inc.
1.67%
Protagonist Therapeutics, Inc.
1.65%
BeOne Medicines Ltd.
1.64%
Kiniksa Pharmaceuticals International Plc
1.63%
Precigen, Inc.
1.62%
Xeris Biopharma Holdings, Inc.
1.61%
ACADIA Pharmaceuticals, Inc.
1.60%
Iovance Biotherapeutics, Inc.
1.60%
Rhythm Pharmaceuticals, Inc.
1.60%
Frequently asked questions about XHE and BBP
How have the XHE and BBP ETFs performed in 2026?
As of September 9, 2026, XHE is up 3.73% year-to-date (YTD), while BBP has returned 32.02%. That puts BBP better performer ahead so far this year.
Which ETF is attracting more investor money: XHE or BBP?
Year-to-date, the XHE ETF saw +$13M in flows, compared to +$50M for BBP.
Which ETF is more volatile: XHE or BBP?
Over the past year, XHE had a volatility of 22.81%, while BBP experienced 25.14%.
Which ETF is bigger: XHE or BBP?
As of September 9, 2026, XHE holds $173.68 M in assets under management (AUM), while BBP manages $115.83 M.
What sectors do the XHE and BBP ETFs invest in?
XHE leans toward sectors like Healthcare. Meanwhile, BBP focuses on Healthcare.
What are the top holdings of the XHE ETF and BBP ETF?
XHE top holdings include AtriCure, Inc., Glaukos Corp. and Dentsply Sirona, Inc.. BBP holds in its top three: Crinetics Pharmaceuticals, Inc., Verastem, Inc. and Nuvation Bio, Inc..
Which ETF is more diversified: XHE or BBP?
XHE holds 66 securities with 30.19% of its assets in the top 15. BBP has 66 securities and a top 15 weight of 26.78%.
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