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WDNAvsIBBQETF Comparison

ETF 1
WDNA

WisdomTree BioRevolution Fund

This fund is part of
BioTech & Genomics
-4.83%
VS
ETF 2
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-0.56%

WisdomTree BioRevolution Fund (WDNA) belongs to the BioTech & Genomics segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. WDNA's top 3 sector exposures are Healthcare, Non-Energy Materials and Consumer Non-Cyclicals. In contrast, IBBQ's top sector exposures are Healthcare and Non-Energy Materials. WDNA is more expensive with a Total Expense Ratio (TER) of 0.45%, versus 0.19% for IBBQ. WDNA is up 38.88% year-to-date (YTD) with +$1M in YTD flows. IBBQ performs worse with 26.71% YTD performance, and +$40M in YTD flows. Run a side-by-side ETF comparison of WDNA and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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WDNA vs IBBQ performance and flow charts

Performance

-6.0-4.0-2.00.02.04.06.0%Oct 2Oct 9Oct 16Oct 23Oct 30

Cumulative Flows

0 M2 M4 M6 M8 M10 MOct 2Oct 9Oct 16Oct 23Oct 30

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Historic performance and flows
Data as of 11/02/2026
1M3MYTD1Y3Y5Y
Perf.
WDNA
IBBQ
-0.28%+3.79%
+20.61%+12.21%
+38.88%+26.71%
+47.68%+36.62%
+77.01%+93.56%
-4.23%+46.05%
Flows
WDNA
IBBQ
+$239K+$10M
+$2M+$37M
+$1M+$40M
+$1M+$56M
+$1M+$75M
+$3M+$53M
Volatility and drawdown
3M1Y3Y5Y
Volatility
WDNA
IBBQ
+38.81%+25.77%
+28.25%+22.57%
+26.82%+21.21%
+26.13%+22.21%
Max drawdown
WDNA
IBBQ
-8.13%-8.58%
-11.90%-8.58%
-36.45%-23.78%
-56.39%-34.86%
Max drawdown duration
WDNA
IBBQ
38d75d
147d75d
595d375d
1825d1429d
Trading data

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WDNA
IBBQ
Last sale
11/2/2026 at 2:30 PM
$23.61
$35.93
Previous close
11/02/2026
$24.11
$35.60
Consolidated volume
11/02/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of October 30, 2026
1-year trailing difference

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WDNA
IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 11/2/2026 at 2:30 PM
Live
Closed
WDNA
IBBQ
Last price
$23.61
$35.93
1D performance
-2.07%
+0.93%
AuM$4.93 M$120.45 M
E/R0.45%0.19%
Characteristics
WDNA
IBBQ
Management strategyPassivePassive
ProviderWisdomTreeInvesco
BenchmarkWisdomTree BioRevolution ESG Screened IndexNASDAQ Biotechnology Index
N° of holdings79245
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateJune 3, 2021June 9, 2021
ESGYesNo
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Exposure

Countries

WDNA
USA
86.29%
Other
13.71%
IBBQ
USA
88.6%
Other
11.4%

Sectors

WDNA
Healthcare
90.77%
Other
9.23%
IBBQ
Healthcare
99.99%
Other
0.01%
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Diversification

WDNA

Total weight of top 15 holdings out of 15

50.08%
IBBQ

Total weight of top 15 holdings out of 15

54.02%

Top 15 holdings

Data as of September 30, 2026
WDNA
Moderna, Inc.
10.44%
Twist Bioscience Corp.
9.31%
10X Genomics, Inc.
3.68%
Eli Lilly & Co.
3.47%
Natera, Inc.
3.09%
Tempus AI, Inc.
2.82%
Johnson & Johnson
2.69%
Iovance Biotherapeutics, Inc.
2.32%
Immunome, Inc.
2.02%
United Therapeutics Corp.
1.86%
Darling Ingredients, Inc.
1.85%
Thermo Fisher Scientific, Inc.
1.75%
Revolution Medicines, Inc.
1.60%
Corteva, Inc.
1.58%
CRISPR Therapeutics AG
1.58%
IBBQ
Gilead Sciences, Inc.
8.32%
Amgen, Inc.
7.78%
Vertex Pharmaceuticals, Inc.
7.75%
Moderna, Inc.
5.16%
Regeneron Pharmaceuticals, Inc.
4.98%
Revolution Medicines, Inc.
2.83%
Illumina, Inc.
2.69%
Alnylam Pharmaceuticals, Inc.
2.24%
Biogen, Inc.
2.21%
Roivant Sciences Ltd.
1.75%
argenx SE
1.74%
Royalty Pharma Plc
1.70%
Insmed, Inc.
1.68%
Incyte Corp.
1.66%
Guardant Health, Inc.
1.56%
Frequently asked questions about WDNA and IBBQ

How have the WDNA and IBBQ ETFs performed in 2026?

As of November 2, 2026, WDNA is up 38.88% year-to-date (YTD), while IBBQ has returned 26.71%. That puts WDNA better performer ahead so far this year.

Which ETF is attracting more investor money: WDNA or IBBQ?

Year-to-date, the WDNA ETF saw +$1M in flows, compared to +$40M for IBBQ.

Which ETF is more volatile: WDNA or IBBQ?

Over the past year, WDNA had a volatility of 28.25%, while IBBQ experienced 22.57%.

Which ETF is bigger: WDNA or IBBQ?

As of November 2, 2026, WDNA holds $4.93 M in assets under management (AUM), while IBBQ manages $120.45 M.

What sectors do the WDNA and IBBQ ETFs invest in?

WDNA leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the WDNA ETF and IBBQ ETF?

WDNA top holdings include Moderna, Inc., Twist Bioscience Corp. and 10X Genomics, Inc.. IBBQ holds in its top three: Gilead Sciences, Inc., Amgen, Inc. and Vertex Pharmaceuticals, Inc..

Which ETF is more diversified: WDNA or IBBQ?

WDNA holds 79 securities with 50.08% of its assets in the top 15. IBBQ has 245 securities and a top 15 weight of 54.02%.

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