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WDNAvsCANCETF Comparison

ETF 1
WDNA

WisdomTree BioRevolution Fund

This fund is part of
BioTech & Genomics
-0.12%
Full WDNA fund page
VS
ETF 2
CANC

Tema Oncology ETF

This fund is part of
Tomorrow's Treatments
-0.38%
Full CANC fund page

WisdomTree BioRevolution Fund (WDNA) belongs to the BioTech & Genomics segment. Tema Oncology ETF (CANC) is part of the Tomorrow's Treatments segment. WDNA's top 3 sector exposures are Health Care, Materials and Consumer Staples. In contrast, CANC's top sector exposures are Health Care,  WDNA is less expensive with a Total Expense Ratio (TER) of 0.45%, versus 0.99% for CANC. WDNA is up 4.96% year-to-date (YTD) with -$357K in YTD flows. CANC performs better with 7.12% YTD performance, and +$41M in YTD flows. Run a side-by-side ETF comparison of WDNA and CANC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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WDNA vs CANC performance and flow charts

Performance

-2.0-1.00.01.02.03.0%Feb 11Feb 19Feb 26Mar 5

Cumulative Flows

0 M2 M4 M6 M8 M10 M12 MFeb 11Feb 19Feb 26Mar 5

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
WDNA
CANC
-0.46%+1.48%
+4.60%+7.25%
+4.96%+7.12%
+38.09%+50.21%
+12.49%n/a
n/an/a
Flows
WDNA
CANC
-$357K+$12M
-$357K+$51M
-$357K+$41M
-$357K+$63M
-$524K-
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
WDNA
CANC
+22.81%+22.49%
+28.57%+24.99%
+24.57%n/a
n/an/a
Max drawdown
WDNA
CANC
-8.60%-4.64%
-17.47%-17.26%
-37.80%n/a
n/an/a
Max drawdown duration
WDNA
CANC
48d29d
106d80d
901dn/a
n/an/a
Trading data

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WDNA
CANC
Last sale
3/12/2026 at 1:30 PM
$17.25
$36.33
Previous close
03/11/2026
$17.67
$37.16
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 12, 2026
1-year trailing difference

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CANC
is actively managed and doesn’t replicate an index

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WDNA
CANC
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/12/2026 at 1:30 PM
Live
Closed
WDNA
CANC
Last price
$17.25
$36.33
1D performance
-2.35%
-2.23%
AuM$2.31 M$165.84 M
E/R0.45%0.99%
Characteristics
WDNA
CANC
Management strategyPassiveActive
ProviderWisdomTreeTema
BenchmarkWisdomTree BioRevolution Index-
N° of holdings7546
Asset classEquities-
Trailing 12m distribution yield
Join
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Inception dateJune 3, 2021August 15, 2023
ESGNoNo
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Exposure

Countries

WDNA
USA
82.35%
Other
17.65%
CANC
USA
88.08%
Other
11.92%

Sectors

WDNA
Health Care
78.82%
Other
21.18%
CANC
Health Care
80.79%
Other
19.21%
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Diversification

WDNA

Total weight of top 15 holdings out of 15

37.91%
CANC

Total weight of top 15 holdings out of 15

56.2%

Top 15 holdings

Data as of January 31, 2026
WDNA
US86366E1064
3.83%
MODERNA INC
3.80%
NATERA
2.81%
LILLY
2.78%
JOHNSON&JOHNSON
2.75%
BIONTECH SE ADR
2.56%
DK0062498333
2.41%
PFIZER
2.34%
STOKE THERAPEUTICS INC
2.15%
AMGEN-T
2.15%
IONIS PHARMACEUTICALS INC
2.12%
BEAM THERAPEUTICS
2.08%
UTD THERAPEUT
2.08%
AMICUS THERAPEUTICS
2.05%
US0463531089
2.03%
CANC
REVOLUTION MEDICINES INC
6.31%
BRIDGEBIO PHARMA
4.61%
NOVARTIS
4.56%
ASTRAZENECA
4.33%
US7711951043
4.14%
LILLY
3.94%
BRISTOL-MYERS SQUIBB
3.89%
US3723032062
3.68%
MERCK & CO INC
3.49%
COGENT BIOSCIENCES
3.42%
NUVALENT
3.25%
IMMUNOME
2.96%
CELCUITY INC
2.67%
AMGEN-T
2.51%
JOHNSON&JOHNSON
2.44%
Frequently asked questions about WDNA and CANC

How have the WDNA and CANC ETFs performed in 2026?

As of March 11, 2026, WDNA is up 4.96% year-to-date (YTD), while CANC has returned 7.12%. That puts CANC better performer ahead so far this year.

Which ETF is attracting more investor money: WDNA or CANC?

Year-to-date, the WDNA ETF saw -$357K in flows, compared to +$41M for CANC.

Which ETF is more volatile: WDNA or CANC?

Over the past year, WDNA had a volatility of 28.57%, while CANC experienced 24.99%.

Which ETF is bigger: WDNA or CANC?

As of March 11, 2026, WDNA holds $2.31 M in assets under management (AUM), while CANC manages $165.84 M.

What sectors do the WDNA and CANC ETFs invest in?

WDNA leans toward sectors like Health Care. Meanwhile, CANC focuses on Health Care.

What are the top holdings of the WDNA ETF and CANC ETF?

WDNA top holdings include US86366E1064, MODERNA INC and NATERA. CANC holds in its top three: REVOLUTION MEDICINES INC, BRIDGEBIO PHARMA and NOVARTIS.

Which ETF is more diversified: WDNA or CANC?

WDNA holds 85 securities with 37.91% of its assets in the top 15. CANC has 56 securities and a top 15 weight of 56.2%.

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