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TMEDvsXLVIETF Comparison

ETF 1
TMED

T. Rowe Price Health Care ETF

This fund is part of
US Health Care
-0.31%
Full TMED fund page
VS
ETF 2
XLVI

The Health Care Select Sector SPDR Premium Income Fund

This fund is part of
Options Strategies
-0.04%
Full XLVI fund page

T. Rowe Price Health Care ETF (TMED) belongs to the US Health Care segment. The Health Care Select Sector SPDR Premium Income Fund (XLVI) is part of the Options Strategies segment. TMED's top 3 sector exposures are Health Care and Financials. In contrast, XLVI's top sector exposures are Health Care  TMED is more expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.35% for XLVI. TMED is up 0.13% year-to-date (YTD) with +$3M in YTD flows. XLVI performs better with 0.28% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of TMED and XLVI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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TMED vs XLVI performance and flow charts

Performance

-1.00.01.02.03.04.0%Feb 10Feb 18Feb 25Mar 4Mar 11

Cumulative Flows

0500,0001,000,0001,500,0002,000,0002,500,0003,000,000Feb 10Feb 18Feb 25Mar 4Mar 11

Get all the metrics on this page, and more, through a reliable ETF data feed

Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/10/2026
1M3MYTD1Y3Y5Y
Perf.
TMED
XLVI
+1.16%-1.07%
+1.57%+1.89%
+0.13%+0.28%
n/an/a
n/an/a
n/an/a
Flows
TMED
XLVI
+$1M+$788K
+$4M+$3M
+$3M+$2M
--
--
--
Volatility and drawdown
3M1Y3Y5Y
Volatility
TMED
XLVI
+16.57%+10.15%
n/an/a
n/an/a
n/an/a
Max drawdown
TMED
XLVI
-7.14%-3.26%
n/an/a
n/an/a
n/an/a
Max drawdown duration
TMED
XLVI
47d10d
n/an/a
n/an/a
n/an/a
Trading data

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TMED
XLVI
Last sale
3/12/2026 at 3:13 PM
$28.95
$25.92
Previous close
03/11/2026
$29.57
$25.98
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
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Main metrics
Last update 3/12/2026 at 3:13 PM
Live
Closed
TMED
XLVI
Last price
$28.95
$25.92
1D performance
-2.11%
-0.23%
AuM$19.32 M$13.24 M
E/R0.44%0.35%
Characteristics
TMED
XLVI
Management strategyActiveActive
ProviderT. Rowe PriceSPDR
Benchmark--
N° of holdings7457
Asset class--
Trailing 12m distribution yield
Join
Join
Inception dateJune 11, 2025July 30, 2025
ESGNoNo
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Exposure

Countries

TMED
USA
85.25%
Other
14.75%
XLVI
USA
96.37%
Other
3.63%

Sectors

TMED
Health Care
86.52%
Other
13.48%
XLVI
Health Care
97.65%
Other
2.35%
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Diversification

TMED

Total weight of top 15 holdings out of 15

56.46%
XLVI

Total weight of top 15 holdings out of 15

69.69%

Top 15 holdings

Data as of January 31, 2026
TMED
LILLY
15.36%
UNITEDHEALTH GRP
6.90%
GILEAD SCIENCES
4.56%
ABBOTT LABS
4.23%
THERMO FISHER SCIENTIFIC
3.98%
DANAHER
3.15%
BECTON DICKINSON AND CO
2.59%
ELANCO ANIMAL HEALTH INC
2.53%
CYTOKINETICS
2.50%
MEDTRONIC PLC
2.22%
ERASCA
1.89%
AMERISOURCEBERGEN
1.78%
STRYKER
1.67%
ARCELLX
1.57%
DYNE THERAPEUTICS INC
1.53%
XLVI
LILLY
14.60%
JOHNSON&JOHNSON
9.71%
ABBVIE
6.99%
MERCK & CO INC
4.85%
UNITEDHEALTH GRP
4.61%
THERMO FISHER SCIENTIFIC
3.85%
ABBOTT LABS
3.37%
AMGEN-T
3.26%
INTUITIVE SURGICAL
3.17%
GILEAD SCIENCES
3.12%
PFIZER
2.66%
BOSTON SCIENTIFIC
2.46%
DANAHER
2.44%
MEDTRONIC PLC
2.34%
STRYKER
2.25%
Frequently asked questions about TMED and XLVI

How have the TMED and XLVI ETFs performed in 2026?

As of March 10, 2026, TMED is up 0.13% year-to-date (YTD), while XLVI has returned 0.28%. That puts XLVI better performer ahead so far this year.

Which ETF is attracting more investor money: TMED or XLVI?

Year-to-date, the TMED ETF saw +$3M in flows, compared to +$2M for XLVI.

Which ETF is bigger: TMED or XLVI?

As of March 10, 2026, TMED holds $19.32 M in assets under management (AUM), while XLVI manages $13.24 M.

What sectors do the TMED and XLVI ETFs invest in?

TMED leans toward sectors like Health Care. Meanwhile, XLVI focuses on Health Care.

What are the top holdings of the TMED ETF and XLVI ETF?

TMED top holdings include LILLY, UNITEDHEALTH GRP and GILEAD SCIENCES. XLVI holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.

Which ETF is more diversified: TMED or XLVI?

TMED holds 80 securities with 56.46% of its assets in the top 15. XLVI has 60 securities and a top 15 weight of 69.69%.

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