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TMEDvsIBBQETF Comparison

ETF 1
TMED

T. Rowe Price Health Care ETF

This fund is part of
US Health Care
-1.03%
VS
ETF 2
IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of
US Health Care
-1.03%

T. Rowe Price Health Care ETF (TMED) and Invesco Nasdaq Biotechnology ETF (IBBQ) belong to the same industry segment: US Health Care. TMED's top 3 sector exposures are Healthcare, Consumer Non-Cyclicals and Non-Corporate. In contrast, IBBQ's top sector exposures are Healthcare and Non-Energy Materials. TMED is more expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.19% for IBBQ. TMED is up 16.23% year-to-date (YTD) with +$15M in YTD flows. IBBQ performs better with 22.86% YTD performance, and +$38M in YTD flows. Run a side-by-side ETF comparison of TMED and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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TMED vs IBBQ performance and flow charts

Performance

-6.0-5.0-4.0-3.0-2.0-1.00.0%Sep 22Sep 29Oct 6Oct 13Oct 20

Cumulative Flows

0 M2 M4 M6 M8 M10 M12 M14 MSep 22Sep 29Oct 6Oct 13Oct 20

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Historic performance and flows
Data as of 10/22/2026
1M3MYTD1Y3Y5Y
Perf.
TMED
IBBQ
-0.47%-0.34%
+2.02%+7.21%
+16.23%+22.86%
+21.78%+36.10%
n/a+90.27%
n/a+44.83%
Flows
TMED
IBBQ
+$2M+$14M
+$10M+$35M
+$15M+$38M
+$16M+$56M
-+$74M
-+$52M
Volatility and drawdown
3M1Y3Y5Y
Volatility
TMED
IBBQ
+19.33%+25.52%
+18.68%+22.48%
n/a+21.25%
n/a+22.22%
Max drawdown
TMED
IBBQ
-10.10%-8.58%
-11.09%-8.58%
n/a-23.78%
n/a-34.86%
Max drawdown duration
TMED
IBBQ
64d65d
125d65d
n/a375d
n/a1429d
Trading data

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TMED
IBBQ
Last sale
10/23/2026 at 1:30 PM
$34.08
$34.52
Previous close
10/22/2026
$34.49
$34.92
Consolidated volume
10/22/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of September 30, 2026
1-year trailing difference

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TMED
is actively managed and doesn’t replicate an index

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TMED
IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 10/23/2026 at 1:30 PM
Live
Closed
TMED
IBBQ
Last price
$34.08
$34.52
1D performance
-1.20%
-1.15%
AuM$34.50 M$115.07 M
E/R0.44%0.19%
Characteristics
TMED
IBBQ
Management strategyActivePassive
ProviderT. Rowe PriceInvesco
Benchmark-NASDAQ Biotechnology Index
N° of holdings106249
Asset class-Equities
Trailing 12m distribution yield
Join
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Inception dateJune 11, 2025June 9, 2021
ESGNoNo
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Exposure

Countries

TMED
USA
92.86%
Other
7.14%
IBBQ
USA
88.22%
Other
11.78%

Sectors

TMED
Healthcare
98.26%
Other
1.74%
IBBQ
Healthcare
99.99%
Other
0.01%
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Diversification

TMED

Total weight of top 15 holdings out of 15

56.93%
IBBQ

Total weight of top 15 holdings out of 15

52.06%

Top 15 holdings

Data as of August 31, 2026
TMED
Eli Lilly & Co.
13.87%
UnitedHealth Group, Inc.
5.32%
Alnylam Pharmaceuticals, Inc.
5.20%
Thermo Fisher Scientific, Inc.
3.74%
Cencora, Inc.
3.65%
Insulet Corp.
3.23%
Gilead Sciences, Inc.
2.99%
Agilent Technologies, Inc.
2.85%
Elanco Animal Health, Inc.
2.63%
Dyne Therapeutics, Inc.
2.47%
Boston Scientific Corp.
2.25%
Stryker Corp.
2.21%
Danaher Corp.
2.20%
Waters Corp.
2.17%
West Pharmaceutical Services, Inc.
2.16%
IBBQ
Amgen, Inc.
8.60%
Vertex Pharmaceuticals, Inc.
8.10%
Gilead Sciences, Inc.
7.34%
Regeneron Pharmaceuticals, Inc.
5.26%
Moderna, Inc.
3.58%
Revolution Medicines, Inc.
2.97%
Illumina, Inc.
2.18%
Biogen, Inc.
2.07%
Alnylam Pharmaceuticals, Inc.
2.00%
argenx SE
1.84%
Royalty Pharma Plc
1.73%
Roivant Sciences Ltd.
1.71%
Insmed, Inc.
1.66%
Incyte Corp.
1.61%
United Therapeutics Corp.
1.42%
Frequently asked questions about TMED and IBBQ

How have the TMED and IBBQ ETFs performed in 2026?

As of October 22, 2026, TMED is up 16.23% year-to-date (YTD), while IBBQ has returned 22.86%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: TMED or IBBQ?

Year-to-date, the TMED ETF saw +$15M in flows, compared to +$38M for IBBQ.

Which ETF is more volatile: TMED or IBBQ?

Over the past year, TMED had a volatility of 18.68%, while IBBQ experienced 22.48%.

Which ETF is bigger: TMED or IBBQ?

As of October 22, 2026, TMED holds $34.50 M in assets under management (AUM), while IBBQ manages $115.07 M.

What sectors do the TMED and IBBQ ETFs invest in?

TMED leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the TMED ETF and IBBQ ETF?

TMED top holdings include Eli Lilly & Co., UnitedHealth Group, Inc. and Alnylam Pharmaceuticals, Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..

Which ETF is more diversified: TMED or IBBQ?

TMED holds 106 securities with 56.93% of its assets in the top 15. IBBQ has 249 securities and a top 15 weight of 52.06%.

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