TMEDvsFBTETF Comparison
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T. Rowe Price Health Care ETF (TMED) and First Trust NYSE Arca Biotechnology Index Fund ETF (FBT) belong to the same industry segment: US Health Care. TMED's top 3 sector exposures are Healthcare, Consumer Non-Cyclicals and Non-Corporate. In contrast, FBT's top sector exposures are Healthcare. TMED is less expensive with a Total Expense Ratio (TER) of 0.44%, versus 0.54% for FBT. TMED is up 16.23% year-to-date (YTD) with +$15M in YTD flows. FBT performs better with 32.37% YTD performance, and +$1.00B in YTD flows. Run a side-by-side ETF comparison of TMED and FBT below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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TMED vs FBT performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/22/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | TMED FBT | -0.47%-0.43% | +2.02%+11.19% | +16.23%+32.37% | +21.78%+45.13% | n/a+100.05% | n/a+67.27% |
| Flows | TMED FBT | +$2M+$40M | +$10M-$71M | +$15M+$1.00B | +$16M+$1.09B | -+$702M | -+$348M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | TMED FBT | +19.33%+22.67% | +18.68%+22.12% | n/a+21.25% | n/a+22.28% |
| Max drawdown | TMED FBT | -10.10%-5.30% | -11.09%-14.27% | n/a-19.92% | n/a-27.40% |
| Max drawdown duration | TMED FBT | 64d56d | 125d126d | n/a237d | n/a1017d |
Trading data
TMED | FBT | |
Last sale 10/23/2026 at 1:30 PM | $34.08 | $269.25 |
| Previous close 10/22/2026 | $34.49 | $272.68 |
| Consolidated volume 10/22/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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TMED
is actively managed and doesn’t replicate an indexTMED | FBT | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/23/2026 at 1:30 PM
Live
Closed
TMED | FBT | |
|---|---|---|
| Last price | $34.08 | $269.25 |
| 1D performance | -1.20% | -1.26% |
| AuM | $34.50 M | $3.01 B |
| E/R | 0.44% | 0.54% |
Characteristics
TMED | FBT | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | T. Rowe Price | First Trust |
| Benchmark | - | NYSE Arca Biotechnology Index |
| N° of holdings | 106 | 30 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 11, 2025 | June 19, 2006 |
| ESG | No | No |
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Exposure
Countries
TMED
USA
92.86%
Other
7.14%
FBT
USA
82.68%
Other
17.32%
Sectors
TMED
Healthcare
98.26%
Other
1.74%
FBT
Healthcare
99.86%
Other
0.14%
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Diversification
TMED
Total weight of top 15 holdings out of 15
56.93%
FBT
Total weight of top 15 holdings out of 15
55.27%
Top 15 holdings
Data as of August 31, 2026
TMED
Eli Lilly & Co.
13.87%
UnitedHealth Group, Inc.
5.32%
Alnylam Pharmaceuticals, Inc.
5.20%
Thermo Fisher Scientific, Inc.
3.74%
Cencora, Inc.
3.65%
Insulet Corp.
3.23%
Gilead Sciences, Inc.
2.99%
Agilent Technologies, Inc.
2.85%
Elanco Animal Health, Inc.
2.63%
Dyne Therapeutics, Inc.
2.47%
Boston Scientific Corp.
2.25%
Stryker Corp.
2.21%
Danaher Corp.
2.20%
Waters Corp.
2.17%
West Pharmaceutical Services, Inc.
2.16%
FBT
Halozyme Therapeutics, Inc.
4.38%
Regeneron Pharmaceuticals, Inc.
3.84%
NeoGenomics, Inc.
3.83%
Corcept Therapeutics, Inc.
3.82%
Amgen, Inc.
3.74%
BeOne Medicines Ltd.
3.72%
Natera, Inc.
3.68%
Repligen Corp.
3.65%
argenx SE
3.63%
Gilead Sciences, Inc.
3.58%
Genmab A/S
3.56%
Vertex Pharmaceuticals, Inc.
3.50%
Sarepta Therapeutics, Inc.
3.49%
BioNTech SE
3.45%
BioMarin Pharmaceutical, Inc.
3.40%
Frequently asked questions about TMED and FBT
How have the TMED and FBT ETFs performed in 2026?
As of October 22, 2026, TMED is up 16.23% year-to-date (YTD), while FBT has returned 32.37%. That puts FBT better performer ahead so far this year.
Which ETF is attracting more investor money: TMED or FBT?
Year-to-date, the TMED ETF saw +$15M in flows, compared to +$1.00B for FBT.
Which ETF is more volatile: TMED or FBT?
Over the past year, TMED had a volatility of 18.68%, while FBT experienced 22.12%.
Which ETF is bigger: TMED or FBT?
As of October 22, 2026, TMED holds $34.50 M in assets under management (AUM), while FBT manages $3.01 B.
What sectors do the TMED and FBT ETFs invest in?
TMED leans toward sectors like Healthcare. Meanwhile, FBT focuses on Healthcare.
What are the top holdings of the TMED ETF and FBT ETF?
TMED top holdings include Eli Lilly & Co., UnitedHealth Group, Inc. and Alnylam Pharmaceuticals, Inc.. FBT holds in its top three: Halozyme Therapeutics, Inc., Regeneron Pharmaceuticals, Inc. and NeoGenomics, Inc..
Which ETF is more diversified: TMED or FBT?
TMED holds 106 securities with 56.93% of its assets in the top 15. FBT has 30 securities and a top 15 weight of 55.27%.
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Latest news about TMED & FBT
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