TDNAvsBBPETF Comparison
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T. Rowe Price Biotech ETF (TDNA) belongs to the Uncategorized Equities segment. Virtus LifeSci Biotech Products ETF (BBP) is part of the Tomorrow's Treatments segment. Both ETFs have the same top 1 sector exposures: Healthcare. TDNA is more expensive with a Total Expense Ratio (TER) of 0.55%, versus 0.34% for BBP. Run a side-by-side ETF comparison of TDNA and BBP below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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TDNA vs BBP performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/29/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | TDNA BBP | +0.68%-0.95% | n/a+7.94% | n/a+30.67% | n/a+42.47% | n/a+125.82% | n/a+94.77% |
| Flows | TDNA BBP | +$568K+$5M | -+$31M | -+$71M | -+$83M | -+$89M | -+$81M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | TDNA BBP | n/a+28.55% | n/a+26.51% | n/a+24.93% | n/a+26.83% |
| Max drawdown | TDNA BBP | n/a-8.70% | n/a-9.59% | n/a-25.54% | n/a-37.61% |
| Max drawdown duration | TDNA BBP | n/a72d | n/a48d | n/a292d | n/a586d |
Trading data
TDNA | BBP | |
Last sale 10/30/2026 at 1:30 PM | $24.89 | $104.18 |
| Previous close 10/29/2026 | $25.17 | $105.26 |
| Consolidated volume 10/29/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of October 30, 2026
1-year trailing difference
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TDNA
is actively managed and doesn’t replicate an indexTDNA | BBP | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/30/2026 at 1:30 PM
Live
Closed
TDNA | BBP | |
|---|---|---|
| Last price | $24.89 | $104.18 |
| 1D performance | -1.11% | -1.03% |
| AuM | $10.69 M | $135.49 M |
| E/R | 0.55% | 0.34% |
Characteristics
TDNA | BBP | |
|---|---|---|
| Management strategy | Active | Passive |
| Provider | T. Rowe Price | VIRTUS Investment Partners |
| Benchmark | - | LifeSci Biotechnology Products Index |
| N° of holdings | 86 | 64 |
| Asset class | - | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 16, 2026 | December 16, 2014 |
| ESG | No | No |
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Exposure
Countries
TDNA
USA
88.46%
Other
11.54%
BBP
USA
85.84%
Other
14.16%
Sectors
TDNA
Healthcare
98.5%
Other
1.5%
BBP
Healthcare
98.4%
Other
1.6%
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Diversification
TDNA
Total weight of top 15 holdings out of 15
37.16%
BBP
Total weight of top 15 holdings out of 15
33.98%
Top 15 holdings
Data as of September 30, 2026
TDNA
argenx SE
5.41%
Kymera Therapeutics, Inc.
4.04%
Kodiak Sciences, Inc.
2.68%
Insmed, Inc.
2.59%
Natera, Inc.
2.41%
Revolution Medicines, Inc.
2.37%
Vertex Pharmaceuticals, Inc.
2.25%
United Therapeutics Corp.
2.20%
Alnylam Pharmaceuticals, Inc.
1.98%
Dianthus Therapeutics, Inc.
1.91%
Praxis Precision Medicines, Inc.
1.91%
Moderna, Inc.
1.90%
Vaxcyte, Inc.
1.86%
Cytokinetics, Inc.
1.83%
Rhythm Pharmaceuticals, Inc.
1.81%
BBP
Moderna, Inc.
5.14%
Iovance Biotherapeutics, Inc.
3.48%
Omeros Corp.
2.96%
Verastem, Inc.
2.43%
Precigen, Inc.
2.25%
Halozyme Therapeutics, Inc.
2.11%
Rigel Pharmaceuticals, Inc.
1.89%
Zai Lab Ltd.
1.89%
Kiniksa Pharmaceuticals International Plc
1.87%
BeOne Medicines Ltd.
1.76%
Xeris Biopharma Holdings, Inc.
1.73%
Protagonist Therapeutics, Inc.
1.67%
Regeneron Pharmaceuticals, Inc.
1.66%
Tarsus Pharmaceuticals, Inc.
1.58%
Sarepta Therapeutics, Inc.
1.57%
Frequently asked questions about TDNA and BBP
Which ETF is bigger: TDNA or BBP?
As of October 29, 2026, TDNA holds $10.69 M in assets under management (AUM), while BBP manages $135.49 M.
What sectors do the TDNA and BBP ETFs invest in?
TDNA leans toward sectors like Healthcare. Meanwhile, BBP focuses on Healthcare.
What are the top holdings of the TDNA ETF and BBP ETF?
TDNA top holdings include argenx SE, Kymera Therapeutics, Inc. and Kodiak Sciences, Inc.. BBP holds in its top three: Moderna, Inc., Iovance Biotherapeutics, Inc. and Omeros Corp..
Which ETF is more diversified: TDNA or BBP?
TDNA holds 86 securities with 37.16% of its assets in the top 15. BBP has 64 securities and a top 15 weight of 33.98%.
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