TDNAvsARKGETF Comparison
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T. Rowe Price Biotech ETF (TDNA) belongs to the Uncategorized Equities segment. ARK Genomic Revolution ETF (ARKG) is part of the BioTech & Genomics segment. Both ETFs have the same top 1 sector exposures: Healthcare. TDNA is less expensive with a Total Expense Ratio (TER) of 0.55%, versus 0.75% for ARKG. Run a side-by-side ETF comparison of TDNA and ARKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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TDNA vs ARKG performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/29/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | TDNA ARKG | +0.68%-5.24% | n/a+30.95% | n/a+76.10% | n/a+72.43% | n/a+128.85% | n/a-33.26% |
| Flows | TDNA ARKG | +$568K+$74M | -+$104M | -+$136M | -+$69M | --$383M | --$1.94B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | TDNA ARKG | n/a+52.42% | n/a+45.41% | n/a+44.98% | n/a+47.01% |
| Max drawdown | TDNA ARKG | n/a-17.81% | n/a-27.52% | n/a-46.41% | n/a-76.56% |
| Max drawdown duration | TDNA ARKG | n/a25d | n/a126d | n/a882d | n/a1821d |
Trading data
TDNA | ARKG | |
Last sale 10/30/2026 at 1:30 PM | $24.89 | $51.40 |
| Previous close 10/29/2026 | $25.17 | $55.11 |
| Consolidated volume 10/29/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
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Main metrics
Last update 10/30/2026 at 1:30 PM
Live
Closed
TDNA | ARKG | |
|---|---|---|
| Last price | $24.89 | $51.40 |
| 1D performance | -1.11% | -6.73% |
| AuM | $10.69 M | $2.21 B |
| E/R | 0.55% | 0.75% |
Characteristics
TDNA | ARKG | |
|---|---|---|
| Management strategy | Active | Active |
| Provider | T. Rowe Price | Ark Investment |
| Benchmark | - | - |
| N° of holdings | 86 | 32 |
| Asset class | - | - |
| Trailing 12m distribution yield | Join | Join |
| Inception date | September 16, 2026 | April 2, 2019 |
| ESG | No | No |
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Exposure
Countries
TDNA
USA
88.46%
Other
11.54%
ARKG
USA
92.01%
Other
7.99%
Sectors
TDNA
Healthcare
98.5%
Other
1.5%
ARKG
Healthcare
99.78%
Other
0.22%
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Diversification
TDNA
Total weight of top 15 holdings out of 15
37.16%
ARKG
Total weight of top 15 holdings out of 15
76.9%
Top 15 holdings
Data as of September 30, 2026
TDNA
argenx SE
5.41%
Kymera Therapeutics, Inc.
4.04%
Kodiak Sciences, Inc.
2.68%
Insmed, Inc.
2.59%
Natera, Inc.
2.41%
Revolution Medicines, Inc.
2.37%
Vertex Pharmaceuticals, Inc.
2.25%
United Therapeutics Corp.
2.20%
Alnylam Pharmaceuticals, Inc.
1.98%
Dianthus Therapeutics, Inc.
1.91%
Praxis Precision Medicines, Inc.
1.91%
Moderna, Inc.
1.90%
Vaxcyte, Inc.
1.86%
Cytokinetics, Inc.
1.83%
Rhythm Pharmaceuticals, Inc.
1.81%
ARKG
Twist Bioscience Corp.
10.31%
10X Genomics, Inc.
10.02%
Tempus AI, Inc.
8.93%
CRISPR Therapeutics AG
5.24%
Absci Corp.
5.06%
Personalis, Inc.
4.88%
Guardant Health, Inc.
4.61%
Natera, Inc.
4.53%
Illumina, Inc.
4.50%
CareDx, Inc.
4.34%
Eli Lilly & Co.
3.35%
Schrödinger, Inc.
3.09%
Beam Therapeutics, Inc.
2.93%
Recursion Pharmaceuticals, Inc.
2.57%
Compass Pathways Plc
2.54%
Frequently asked questions about TDNA and ARKG
Which ETF is bigger: TDNA or ARKG?
As of October 29, 2026, TDNA holds $10.69 M in assets under management (AUM), while ARKG manages $2.21 B.
What sectors do the TDNA and ARKG ETFs invest in?
TDNA leans toward sectors like Healthcare. Meanwhile, ARKG focuses on Healthcare.
What are the top holdings of the TDNA ETF and ARKG ETF?
TDNA top holdings include argenx SE, Kymera Therapeutics, Inc. and Kodiak Sciences, Inc.. ARKG holds in its top three: Twist Bioscience Corp., 10X Genomics, Inc. and Tempus AI, Inc..
Which ETF is more diversified: TDNA or ARKG?
TDNA holds 86 securities with 37.16% of its assets in the top 15. ARKG has 32 securities and a top 15 weight of 76.9%.
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Latest news about TDNA & ARKG
The Weekly ETF Market Monitor (October 19-23, 2026)
October 26, 2026
ARKG
Biotech ETFs – Investing in Health Innovation
July 21, 2022
ARKG
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