PTHvsIBRNETF Comparison
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Invesco DWA Healthcare Momentum ETF (PTH) belongs to the US Health Care segment. iShares Neuroscience and Healthcare ETF (IBRN) is part of the Healthcare Technology segment. Both ETFs have the same top 3 sector exposures: and Healthcare. PTH is more expensive with a Total Expense Ratio (TER) of 0.72%, versus 0.47% for IBRN. PTH is up 17.82% year-to-date (YTD) with +$88M in YTD flows. IBRN performs worse with 16.7% YTD performance, and - in YTD flows. Run a side-by-side ETF comparison of PTH and IBRN below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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PTH vs IBRN performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PTH IBRN | +5.19%+1.23% | +12.36%+9.21% | +17.82%+16.70% | +58.30%+63.17% | +56.89%+56.08% | +7.61%n/a |
| Flows | PTH IBRN | +$102M- | +$94M- | +$88M- | +$92M- | +$25M-$1M | -$192M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PTH IBRN | +29.53%+24.90% | +24.63%+25.46% | +25.60%+24.99% | +25.58%n/a |
| Max drawdown | PTH IBRN | -8.31%-8.16% | -11.91%-8.68% | -27.71%-34.98% | -50.10%n/a |
| Max drawdown duration | PTH IBRN | 41d15d | 140d75d | 353d338d | 1756dn/a |
Trading data
PTH | IBRN | |
Last sale 7/24/2026 at 1:30 PM | $58.57 | $37.69 |
| Previous close 07/23/2026 | $59.39 | $37.77 |
| Consolidated volume 07/23/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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PTH | IBRN | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/24/2026 at 1:30 PM
Live
Closed
PTH | IBRN | |
|---|---|---|
| Last price | $58.57 | $37.69 |
| 1D performance | -1.38% | -0.20% |
| AuM | $231.95 M | $5.66 M |
| E/R | 0.72% | 0.47% |
Characteristics
PTH | IBRN | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | iShares |
| Benchmark | Dorsey Wright Healthcare Technical Leaders Index | NYSE FactSet Global Neuro Biopharma and MedTech Index |
| N° of holdings | 57 | 70 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | October 12, 2006 | August 24, 2022 |
| ESG | No | No |
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Exposure
Countries
PTH
USA
92.25%
Other
7.75%
IBRN
USA
77.98%
Other
22.02%
Sectors
PTH
Healthcare
100%
Other
0%
IBRN
Healthcare
99.9%
Other
0.1%
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Diversification
PTH
Total weight of top 15 holdings out of 15
43.88%
IBRN
Total weight of top 15 holdings out of 15
60.92%
Top 15 holdings
Data as of June 30, 2026
PTH
Roivant Sciences Ltd.
4.95%
Praxis Precision Medicines, Inc.
4.66%
Tango Therapeutics, Inc.
3.70%
SELLAS Life Sciences Group, Inc.
3.36%
United Therapeutics Corp.
2.91%
Tenet Healthcare Corp.
2.89%
Axsome Therapeutics, Inc.
2.74%
BrightSpring Health Services, Inc.
2.54%
Liquidia Corp.
2.52%
Moderna, Inc.
2.49%
Ionis Pharmaceuticals, Inc.
2.30%
Erasca, Inc.
2.29%
HCA Healthcare, Inc.
2.23%
Twist Bioscience Corp.
2.21%
Protagonist Therapeutics, Inc.
2.08%
IBRN
Praxis Precision Medicines, Inc.
4.79%
Scholar Rock Holding Corp.
4.53%
Alkermes Plc
4.47%
Dianthus Therapeutics, Inc.
4.42%
Xenon Pharmaceuticals, Inc.
4.26%
PTC Therapeutics, Inc.
4.20%
ACADIA Pharmaceuticals, Inc.
4.17%
Arrowhead Pharmaceuticals, Inc.
4.07%
Biogen, Inc.
4.04%
Axsome Therapeutics, Inc.
3.85%
argenx SE
3.80%
Neurocrine Biosciences, Inc.
3.76%
Denali Therapeutics, Inc.
3.73%
Catalyst Pharmaceuticals, Inc.
3.42%
BlackRock Cash Funds - Treasury
3.40%
Frequently asked questions about PTH and IBRN
How have the PTH and IBRN ETFs performed in 2026?
As of July 24, 2026, PTH is up 17.82% year-to-date (YTD), while IBRN has returned 16.7%. That puts PTH better performer ahead so far this year.
Which ETF is attracting more investor money: PTH or IBRN?
Year-to-date, the PTH ETF saw +$88M in flows, compared to - for IBRN.
Which ETF is more volatile: PTH or IBRN?
Over the past year, PTH had a volatility of 24.63%, while IBRN experienced 25.46%.
Which ETF is bigger: PTH or IBRN?
As of July 24, 2026, PTH holds $231.95 M in assets under management (AUM), while IBRN manages $5.66 M.
What sectors do the PTH and IBRN ETFs invest in?
PTH leans toward sectors like Healthcare. Meanwhile, IBRN focuses on Healthcare.
What are the top holdings of the PTH ETF and IBRN ETF?
PTH top holdings include Roivant Sciences Ltd., Praxis Precision Medicines, Inc. and Tango Therapeutics, Inc.. IBRN holds in its top three: Praxis Precision Medicines, Inc., Scholar Rock Holding Corp. and Alkermes Plc.
Which ETF is more diversified: PTH or IBRN?
PTH holds 57 securities with 43.88% of its assets in the top 15. IBRN has 70 securities and a top 15 weight of 60.92%.
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Latest news about PTH & IBRN
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