PSCHvsIBRNETF Comparison
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Invesco S&P SmallCap Health Care ETF (PSCH) belongs to the US Health Care segment. iShares Neuroscience and Healthcare ETF (IBRN) is part of the Healthcare Technology segment. PSCH's top 1 sector exposures are Healthcare. In contrast, IBRN's top sector exposures are Healthcare and Non-Corporate. PSCH is less expensive with a Total Expense Ratio (TER) of 0.29%, versus 0.47% for IBRN. PSCH is up 21.86% year-to-date (YTD) with +$7M in YTD flows. IBRN performs worse with 19.13% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of PSCH and IBRN below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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PSCH vs IBRN performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 09/09/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PSCH IBRN | -2.89%-1.82% | +13.44%+13.29% | +21.86%+19.13% | +30.10%+50.71% | +36.07%+73.10% | -13.90%n/a |
| Flows | PSCH IBRN | +$14M- | +$25M+$2M | +$7M+$2M | +$2M+$2M | -$109M+$759K | -$207M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PSCH IBRN | +15.73%+24.37% | +19.67%+25.87% | +21.83%+25.19% | +22.87%n/a |
| Max drawdown | PSCH IBRN | -4.27%-9.28% | -15.36%-9.28% | -22.80%-34.98% | -45.76%n/a |
| Max drawdown duration | PSCH IBRN | 21d40d | 168d40d | 488d338d | 1766dn/a |
Trading data
PSCH | IBRN | |
Last sale 9/10/2026 at 1:30 PM | $53.11 | $37.33 |
| Previous close 09/09/2026 | $53.71 | $38.00 |
| Consolidated volume 09/09/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of August 31, 2026
1-year trailing difference
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PSCH | IBRN | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 9/10/2026 at 1:30 PM
Live
Closed
PSCH | IBRN | |
|---|---|---|
| Last price | $53.11 | $37.33 |
| 1D performance | -1.12% | -1.75% |
| AuM | $181.59 M | $7.70 M |
| E/R | 0.29% | 0.47% |
Characteristics
PSCH | IBRN | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | iShares |
| Benchmark | S&P SmallCap 600 Capped Health Care Index | NYSE FactSet Global Neuro Biopharma and MedTech Index |
| N° of holdings | 69 | 69 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 7, 2010 | August 24, 2022 |
| ESG | No | No |
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Exposure
Countries
PSCH
USA
95.04%
Other
4.96%
IBRN
USA
73.57%
Other
26.43%
Sectors
PSCH
Healthcare
100%
Other
0%
IBRN
Healthcare
99.87%
Other
0.13%
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Diversification
PSCH
Total weight of top 15 holdings out of 15
48.1%
IBRN
Total weight of top 15 holdings out of 15
64.26%
Top 15 holdings
Data as of July 31, 2026
PSCH
Glaukos Corp.
4.96%
Corcept Therapeutics, Inc.
4.64%
Alkermes Plc
4.21%
Protagonist Therapeutics, Inc.
4.20%
TG Therapeutics, Inc.
3.68%
PTC Therapeutics, Inc.
3.23%
Liquidia Corp.
3.19%
Teleflex, Inc.
3.11%
Ligand Pharmaceuticals, Inc.
3.01%
Indivior Pharmaceuticals, Inc.
2.55%
Merit Medical Systems, Inc.
2.52%
RadNet, Inc.
2.34%
Veracyte, Inc.
2.32%
ICU Medical, Inc.
2.17%
Concentra Group Holdings Parent, Inc.
1.96%
IBRN
Dianthus Therapeutics, Inc.
5.45%
Xenon Pharmaceuticals, Inc.
4.83%
Praxis Precision Medicines, Inc.
4.72%
ACADIA Pharmaceuticals, Inc.
4.66%
Arrowhead Pharmaceuticals, Inc.
4.65%
Alkermes Plc
4.55%
Neurocrine Biosciences, Inc.
4.41%
Scholar Rock Holding Corp.
4.31%
PTC Therapeutics, Inc.
4.15%
Biogen, Inc.
4.15%
Axsome Therapeutics, Inc.
3.93%
argenx SE
3.82%
Denali Therapeutics, Inc.
3.76%
Dyne Therapeutics, Inc.
3.53%
Edgewise Therapeutics, Inc.
3.35%
Frequently asked questions about PSCH and IBRN
How have the PSCH and IBRN ETFs performed in 2026?
As of September 9, 2026, PSCH is up 21.86% year-to-date (YTD), while IBRN has returned 19.13%. That puts PSCH better performer ahead so far this year.
Which ETF is attracting more investor money: PSCH or IBRN?
Year-to-date, the PSCH ETF saw +$7M in flows, compared to +$2M for IBRN.
Which ETF is more volatile: PSCH or IBRN?
Over the past year, PSCH had a volatility of 19.67%, while IBRN experienced 25.87%.
Which ETF is bigger: PSCH or IBRN?
As of September 9, 2026, PSCH holds $181.59 M in assets under management (AUM), while IBRN manages $7.70 M.
What sectors do the PSCH and IBRN ETFs invest in?
PSCH leans toward sectors like Healthcare. Meanwhile, IBRN focuses on Healthcare.
What are the top holdings of the PSCH ETF and IBRN ETF?
PSCH top holdings include Glaukos Corp., Corcept Therapeutics, Inc. and Alkermes Plc. IBRN holds in its top three: Dianthus Therapeutics, Inc., Xenon Pharmaceuticals, Inc. and Praxis Precision Medicines, Inc..
Which ETF is more diversified: PSCH or IBRN?
PSCH holds 69 securities with 48.1% of its assets in the top 15. IBRN has 69 securities and a top 15 weight of 64.26%.
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