PSCHvsIBRNETF Comparison
VS
Invesco S&P SmallCap Health Care ETF (PSCH) belongs to the US Health Care segment. iShares Neuroscience and Healthcare ETF (IBRN) is part of the Healthcare Technology segment. PSCH's top 1 sector exposures are Healthcare. In contrast, IBRN's top sector exposures are Healthcare and Non-Corporate. PSCH is less expensive with a Total Expense Ratio (TER) of 0.29%, versus 0.47% for IBRN. PSCH is up 22.45% year-to-date (YTD) with -$1M in YTD flows. IBRN performs worse with -3.08% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of PSCH and IBRN below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
Find out how industry players manage ETF portfolios. Discover our library of Model portfolios
PSCH vs IBRN performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/23/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PSCH IBRN | +2.58%-8.14% | +1.83%-17.21% | +22.45%-3.08% | +26.77%+9.13% | +52.89%+61.85% | -9.76%n/a |
| Flows | PSCH IBRN | -$13M- | +$10M+$2M | -$1M+$2M | -$1M+$2M | -$102M+$759K | -$210M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PSCH IBRN | +16.86%+25.93% | +19.43%+26.78% | +21.81%+25.48% | +22.92%n/a |
| Max drawdown | PSCH IBRN | -8.61%-26.38% | -15.36%-26.38% | -22.80%-34.98% | -45.76%n/a |
| Max drawdown duration | PSCH IBRN | 65d65d | 168d65d | 488d338d | 1810dn/a |
Trading data
PSCH | IBRN | |
Last sale 10/23/2026 at 1:30 PM | $54.00 | $31.36 |
| Previous close 10/22/2026 | $54.29 | $31.75 |
| Consolidated volume 10/22/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
Create an account to view replication metrics
Join for free
PSCH | IBRN | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
Advertisement
Main metrics
Last update 10/23/2026 at 1:30 PM
Live
Closed
PSCH | IBRN | |
|---|---|---|
| Last price | $54.00 | $31.36 |
| 1D performance | -0.53% | -1.21% |
| AuM | $173.83 M | $6.26 M |
| E/R | 0.29% | 0.47% |
Characteristics
PSCH | IBRN | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | iShares |
| Benchmark | S&P SmallCap 600 Capped Health Care Index | NYSE FactSet Global Neuro Biopharma and MedTech Index |
| N° of holdings | 69 | 69 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | April 7, 2010 | August 24, 2022 |
| ESG | No | No |
Advertisement
Exposure
Countries
PSCH
USA
94.93%
Other
5.07%
IBRN
USA
73.41%
Other
26.59%
Sectors
PSCH
Healthcare
100%
Other
0%
IBRN
Healthcare
99.86%
Other
0.14%
Advertisement
Diversification
PSCH
Total weight of top 15 holdings out of 15
48.62%
IBRN
Total weight of top 15 holdings out of 15
62.03%
Top 15 holdings
Data as of August 31, 2026
PSCH
Corcept Therapeutics, Inc.
5.61%
Glaukos Corp.
5.37%
Protagonist Therapeutics, Inc.
4.54%
Alkermes Plc
4.09%
TG Therapeutics, Inc.
3.69%
Teleflex, Inc.
3.06%
PTC Therapeutics, Inc.
2.99%
Ligand Pharmaceuticals, Inc.
2.87%
Merit Medical Systems, Inc.
2.68%
RadNet, Inc.
2.68%
Liquidia Corp.
2.47%
ICU Medical, Inc.
2.20%
Indivior Pharmaceuticals, Inc.
2.16%
Integer Holdings Corp.
2.14%
Concentra Group Holdings Parent, Inc.
2.07%
IBRN
Praxis Precision Medicines, Inc.
5.21%
Dianthus Therapeutics, Inc.
4.96%
ACADIA Pharmaceuticals, Inc.
4.93%
Scholar Rock Holding Corp.
4.85%
Xenon Pharmaceuticals, Inc.
4.40%
argenx SE
4.37%
Arrowhead Pharmaceuticals, Inc.
4.26%
Biogen, Inc.
4.19%
Alkermes Plc
4.15%
PTC Therapeutics, Inc.
3.70%
Denali Therapeutics, Inc.
3.56%
Neurocrine Biosciences, Inc.
3.55%
Dyne Therapeutics, Inc.
3.38%
Edgewise Therapeutics, Inc.
3.30%
Axsome Therapeutics, Inc.
3.23%
Frequently asked questions about PSCH and IBRN
How have the PSCH and IBRN ETFs performed in 2026?
As of October 23, 2026, PSCH is up 22.45% year-to-date (YTD), while IBRN has lost -3.08%. That puts PSCH better performer ahead so far this year.
Which ETF is attracting more investor money: PSCH or IBRN?
Year-to-date, the PSCH ETF saw -$1M in flows, compared to +$2M for IBRN.
Which ETF is more volatile: PSCH or IBRN?
Over the past year, PSCH had a volatility of 19.43%, while IBRN experienced 26.78%.
Which ETF is bigger: PSCH or IBRN?
As of October 23, 2026, PSCH holds $173.83 M in assets under management (AUM), while IBRN manages $6.26 M.
What sectors do the PSCH and IBRN ETFs invest in?
PSCH leans toward sectors like Healthcare. Meanwhile, IBRN focuses on Healthcare.
What are the top holdings of the PSCH ETF and IBRN ETF?
PSCH top holdings include Corcept Therapeutics, Inc., Glaukos Corp. and Protagonist Therapeutics, Inc.. IBRN holds in its top three: Praxis Precision Medicines, Inc., Dianthus Therapeutics, Inc. and ACADIA Pharmaceuticals, Inc..
Which ETF is more diversified: PSCH or IBRN?
PSCH holds 69 securities with 48.62% of its assets in the top 15. IBRN has 69 securities and a top 15 weight of 62.03%.
Advertisement
Advertisement
