PBEvsIHIETF Comparison
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Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the BioTech & Genomics segment. iShares U.S. Medical Devices ETF (IHI) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. PBE is more expensive with a Total Expense Ratio (TER) of 0.58%, versus 0.38% for IHI. PBE is down -2.66% year-to-date (YTD) with -$2M in YTD flows. IHI performs worse with -14.99% YTD performance, and -$236M in YTD flows. Run a side-by-side ETF comparison of PBE and IHI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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PBE vs IHI performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 04/24/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PBE IHI | +4.27%-2.40% | -3.98%-13.04% | -2.66%-14.99% | +32.11%-10.54% | +28.24%-6.36% | +3.38%-10.49% |
| Flows | PBE IHI | +$2M+$68M | -$6M-$197M | -$2M-$236M | -$30M-$893M | -$58M-$2.87B | -$43M-$4.89B |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PBE IHI | +19.57%+18.24% | +19.83%+15.91% | +20.15%+16.75% | +22.54%+18.85% |
| Max drawdown | PBE IHI | -9.36%-13.90% | -11.70%-18.81% | -22.21%-22.87% | -34.74%-33.07% |
| Max drawdown duration | PBE IHI | 75d88d | 107d150d | 324d210d | 1540d1689d |
Trading data
PBE | IHI | |
Last sale 4/27/2026 at 1:30 PM | $79.93 | $52.72 |
| Previous close 04/24/2026 | $79.82 | $52.81 |
| Consolidated volume 04/24/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of March 31, 2026
1-year trailing difference
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PBE | IHI | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
PBE | IHI | |
|---|---|---|
| Last price | $79.93 | $52.72 |
| 1D performance | +0.14% | -0.17% |
| AuM | $249.88 M | $3.23 B |
| E/R | 0.58% | 0.38% |
Characteristics
PBE | IHI | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | iShares |
| Benchmark | Dynamic Biotech & Genome Intellidex Index | Dow Jones U.S. Select Medical Equipment Index |
| N° of holdings | 30 | 46 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 23, 2005 | May 1, 2006 |
| ESG | No | No |
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Exposure
Countries
PBE
USA
92.18%
Other
7.82%
IHI
USA
91.73%
Ireland
7.56%
Other
0.7%
Sectors
PBE
Health Care
97.59%
Other
2.41%
IHI
Health Care
95.39%
Other
4.61%
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Diversification
PBE
Total weight of top 15 holdings out of 15
63.66%
IHI
Total weight of top 15 holdings out of 15
87.45%
Top 15 holdings
Data as of March 31, 2026
PBE
UTD THERAPEUT
6.05%
ILLUMINA
5.24%
REGENERON PHARMACEUTICALS
5.23%
ALNYLAM PHARMACEUTICALS
5.22%
BIOGEN INC
5.16%
AMGEN-T
4.99%
GILEAD SCIENCES
4.98%
INCYTE
4.89%
BIOCRYST PHARMACEUTICALS
3.66%
PROTAGONIST THERAPEUTICS INC
3.38%
TG THERAPEUTICS
3.11%
ROYALTY PHARMA
3.05%
NEUROCRINE BIOSCIENCES
2.93%
CATALYST PHARMACEUTICALS INC
2.89%
PTC THERAPEUTI/D
2.86%
IHI
ABBOTT LABS
16.98%
INTUITIVE SURGICAL
15.57%
STRYKER
10.76%
MEDTRONIC PLC
4.62%
BECTON DICKINSON AND CO
4.57%
EDWARDS LIFESCIENCES
4.47%
IDEXX LABORATORIES
4.44%
RESMED
4.43%
US36266G1076
4.40%
BOSTON SCIENTIFIC
4.28%
DEXCOM
3.28%
STERIS
2.94%
ZIMMER BIOMET HOLDINGS INC
2.43%
HOLOGIC
2.28%
INSULET
2.00%
Frequently asked questions about PBE and IHI
How have the PBE and IHI ETFs performed in 2026?
As of April 24, 2026, PBE is down -2.66% year-to-date (YTD), while IHI has lost -14.99%. That puts PBE better performer ahead so far this year.
Which ETF is attracting more investor money: PBE or IHI?
Year-to-date, the PBE ETF saw -$2M in flows, compared to -$236M for IHI.
Which ETF is more volatile: PBE or IHI?
Over the past year, PBE had a volatility of 19.83%, while IHI experienced 15.91%.
Which ETF is bigger: PBE or IHI?
As of April 24, 2026, PBE holds $249.88 M in assets under management (AUM), while IHI manages $3.23 B.
What sectors do the PBE and IHI ETFs invest in?
PBE leans toward sectors like Health Care. Meanwhile, IHI focuses on Health Care.
What are the top holdings of the PBE ETF and IHI ETF?
PBE top holdings include UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS. IHI holds in its top three: ABBOTT LABS, INTUITIVE SURGICAL and STRYKER.
Which ETF is more diversified: PBE or IHI?
PBE holds 30 securities with 63.66% of its assets in the top 15. IHI has 48 securities and a top 15 weight of 87.45%.
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Latest news about PBE & IHI
Notable ETF Filings Recap: April 2024
May 2, 2024
IHI
Health Care Sector Down After a Cyberattack on UnitedHealth
March 4, 2024
IHI
Investing in the Aging Demographics Megatrend
February 28, 2023
IHI
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