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PBEvsIBBQETF Comparison

ETF 1

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

+0.97%

Full PBE fund page

VS

ETF 2

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

+0.14%

Full IBBQ fund page

Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the BioTech & Genomics segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. PBE's top 1 sector exposures are Healthcare. In contrast, IBBQ's top sector exposures are Healthcare and Non-Energy Materials. PBE is more expensive with a Total Expense Ratio (TER) of 0.59%, versus 0.19% for IBBQ. PBE is up 22.24% year-to-date (YTD) with +$113M in YTD flows. IBBQ performs better with 23.33% YTD performance, and +$38M in YTD flows. Run a side-by-side ETF comparison of PBE and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PBE vs IBBQ performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 10/26/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	PBE IBBQ	+2.00%-1.52%	+10.62%+7.85%	+22.24%+23.33%	+36.49%+33.67%	+87.45%+91.50%	+34.51%+45.44%
Flows	PBE IBBQ	-$947K+$14M	+$111M+$35M	+$113M+$38M	+$115M+$55M	+$62M+$74M	+$65M+$52M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	PBE IBBQ	+21.57%+25.69%	+20.01%+22.47%	+20.66%+21.24%	+22.69%+22.22%
Max drawdown	PBE IBBQ	-5.97%-8.58%	-11.70%-8.58%	-22.21%-23.78%	-32.63%-34.86%
Max drawdown duration	PBE IBBQ	46d68d	166d68d	324d375d	1468d1429d

Trading data

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	PBE	IBBQ
Last sale 10/27/2026 at 1:30 PM	$100.74	$35.38
Previous close 10/26/2026	$99.21	$34.68
Consolidated volume 10/26/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of September 30, 2026

1-year trailing difference

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	PBE	IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 10/27/2026 at 1:30 PM

Live

Closed

	PBE	IBBQ
Last price	$100.74	$35.38
1D performance	+1.54%	+2.01%
AuM	$431.86 M	$115.51 M
E/R	0.59%	0.19%

Characteristics

	PBE	IBBQ
Management strategy	Passive	Passive
Provider	Invesco	Invesco
Benchmark	Dynamic Biotech & Genome Intellidex Index	NASDAQ Biotechnology Index
N° of holdings	30	249
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 23, 2005	June 9, 2021
ESG	No	No

More PBE data on Trackinsight

More IBBQ data on Trackinsight

Exposure

Countries

PBE

USA

97.22%

Other

2.78%

IBBQ

USA

88.22%

Other

11.78%

Sectors

PBE

Healthcare

100%

Other

0%

IBBQ

Healthcare

99.99%

Other

0.01%

Diversification

PBE

Total weight of top 15 holdings out of 15

63.67%

IBBQ

Total weight of top 15 holdings out of 15

52.06%

Top 15 holdings

Data as of August 31, 2026

PBE

CareDx, Inc.

5.49%

Amgen, Inc.

5.38%

Regeneron Pharmaceuticals, Inc.

5.26%

Vertex Pharmaceuticals, Inc.

5.21%

Royalty Pharma Plc

4.76%

Biogen, Inc.

4.75%

Gilead Sciences, Inc.

4.61%

United Therapeutics Corp.

3.77%

Omeros Corp.

3.73%

Repligen Corp.

3.57%

Illumina, Inc.

3.54%

Halozyme Therapeutics, Inc.

3.51%

Bio-Techne Corp.

3.41%

Protagonist Therapeutics, Inc.

3.37%

Alnylam Pharmaceuticals, Inc.

3.31%

IBBQ

Amgen, Inc.

8.60%

Vertex Pharmaceuticals, Inc.

8.10%

Gilead Sciences, Inc.

7.34%

Regeneron Pharmaceuticals, Inc.

5.26%

Moderna, Inc.

3.58%

Revolution Medicines, Inc.

2.97%

Illumina, Inc.

2.18%

Biogen, Inc.

2.07%

Alnylam Pharmaceuticals, Inc.

2.00%

argenx SE

1.84%

Royalty Pharma Plc

1.73%

Roivant Sciences Ltd.

1.71%

Insmed, Inc.

1.66%

Incyte Corp.

1.61%

United Therapeutics Corp.

1.42%

Frequently asked questions about PBE and IBBQ

How have the PBE and IBBQ ETFs performed in 2026?

As of October 26, 2026, PBE is up 22.24% year-to-date (YTD), while IBBQ has returned 23.33%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or IBBQ?

Year-to-date, the PBE ETF saw +$113M in flows, compared to +$38M for IBBQ.

Which ETF is more volatile: PBE or IBBQ?

Over the past year, PBE had a volatility of 20.01%, while IBBQ experienced 22.47%.

Which ETF is bigger: PBE or IBBQ?

As of October 26, 2026, PBE holds $431.86 M in assets under management (AUM), while IBBQ manages $115.51 M.

What sectors do the PBE and IBBQ ETFs invest in?

PBE leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the PBE ETF and IBBQ ETF?

PBE top holdings include CareDx, Inc., Amgen, Inc. and Regeneron Pharmaceuticals, Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..

PBEvsIBBQETF Comparison

Invesco Dynamic Biotechnology & Genome ETF

Invesco Nasdaq Biotechnology ETF

PBE vs IBBQ performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the PBE and IBBQ ETFs performed in 2026?

As of October 26, 2026, PBE is up 22.24% year-to-date (YTD), while IBBQ has returned 23.33%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or IBBQ?

Year-to-date, the PBE ETF saw +$113M in flows, compared to +$38M for IBBQ.

Which ETF is more volatile: PBE or IBBQ?

Over the past year, PBE had a volatility of 20.01%, while IBBQ experienced 22.47%.

Which ETF is bigger: PBE or IBBQ?

As of October 26, 2026, PBE holds $431.86 M in assets under management (AUM), while IBBQ manages $115.51 M.

What sectors do the PBE and IBBQ ETFs invest in?

PBE leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.

What are the top holdings of the PBE ETF and IBBQ ETF?

PBE top holdings include CareDx, Inc., Amgen, Inc. and Regeneron Pharmaceuticals, Inc.. IBBQ holds in its top three: Amgen, Inc., Vertex Pharmaceuticals, Inc. and Gilead Sciences, Inc..

Which ETF is more diversified: PBE or IBBQ?

PBE holds 30 securities with 63.67% of its assets in the top 15. IBBQ has 249 securities and a top 15 weight of 52.06%.

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