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PBEvsIBBQETF Comparison

ETF 1

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

-0.67%

Full PBE fund page

VS

ETF 2

IBBQ

Invesco Nasdaq Biotechnology ETF

This fund is part of

US Health Care

-1.08%

Full IBBQ fund page

Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the BioTech & Genomics segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. PBE is more expensive with a Total Expense Ratio (TER) of 0.58%, versus 0.19% for IBBQ. PBE is down -2.66% year-to-date (YTD) with -$2M in YTD flows. IBBQ performs better with 3.49% YTD performance, and +$290K in YTD flows. Run a side-by-side ETF comparison of PBE and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PBE vs IBBQ performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	PBE IBBQ	+4.27%+5.67%	-3.98%-0.91%	-2.66%+3.49%	+32.11%+41.67%	+28.24%+41.72%	+3.38%n/a
Flows	PBE IBBQ	+$2M-$8M	-$6M-$9M	-$2M+$290K	-$30M+$14M	-$58M+$34M	-$43M-

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	PBE IBBQ	+19.57%+22.23%	+19.83%+21.05%	+20.15%+19.62%	+22.54%n/a
Max drawdown	PBE IBBQ	-9.36%-8.38%	-11.70%-8.39%	-22.21%-23.78%	-34.74%n/a
Max drawdown duration	PBE IBBQ	75d48d	107d33d	324d375d	1540dn/a

Trading data

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	PBE	IBBQ
Last sale 4/27/2026 at 1:30 PM	$79.93	$29.23
Previous close 04/24/2026	$79.82	$29.34
Consolidated volume 04/24/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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	PBE	IBBQ
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/27/2026 at 1:30 PM

Live

Closed

	PBE	IBBQ
Last price	$79.93	$29.23
1D performance	+0.14%	-0.36%
AuM	$249.88 M	$66.29 M
E/R	0.58%	0.19%

Characteristics

	PBE	IBBQ
Management strategy	Passive	Passive
Provider	Invesco	Invesco
Benchmark	Dynamic Biotech & Genome Intellidex Index	NASDAQ Biotechnology Index
N° of holdings	30	192
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 23, 2005	June 9, 2021
ESG	No	No

More PBE data on Trackinsight

More IBBQ data on Trackinsight

Exposure

Countries

PBE

USA

92.18%

Other

7.82%

IBBQ

USA

92.77%

Other

7.23%

Sectors

PBE

Health Care

97.59%

Other

2.41%

IBBQ

Health Care

85.9%

Other

14.1%

Diversification

PBE

Total weight of top 15 holdings out of 15

63.66%

IBBQ

Total weight of top 15 holdings out of 15

51.37%

Top 15 holdings

Data as of March 31, 2026

PBE

UTD THERAPEUT

6.05%

ILLUMINA

5.24%

REGENERON PHARMACEUTICALS

5.23%

ALNYLAM PHARMACEUTICALS

5.22%

BIOGEN INC

5.16%

AMGEN-T

4.99%

GILEAD SCIENCES

4.98%

INCYTE

4.89%

BIOCRYST PHARMACEUTICALS

3.66%

PROTAGONIST THERAPEUTICS INC

3.38%

TG THERAPEUTICS

3.11%

ROYALTY PHARMA

3.05%

NEUROCRINE BIOSCIENCES

2.93%

CATALYST PHARMACEUTICALS INC

2.89%

PTC THERAPEUTI/D

2.86%

IBBQ

GILEAD SCIENCES

7.85%

AMGEN-T

7.82%

VERTEX PHARMACEUTICALS

7.59%

REGENERON PHARMACEUTICALS

6.48%

ALNYLAM PHARMACEUTICALS

3.56%

INSMED

2.65%

BIOGEN INC

2.28%

UTD THERAPEUT

1.94%

ROYALTY PHARMA

1.68%

US04016X1019

1.66%

MODERNA INC

1.66%

ROIVANT SCIENCES LTD

1.61%

REVOLUTION MEDICINES INC

1.55%

ILLUMINA

1.52%

INCYTE

1.52%

Frequently asked questions about PBE and IBBQ

How have the PBE and IBBQ ETFs performed in 2026?

As of April 24, 2026, PBE is down -2.66% year-to-date (YTD), while IBBQ has returned 3.49%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or IBBQ?

Year-to-date, the PBE ETF saw -$2M in flows, compared to +$290K for IBBQ.

Which ETF is more volatile: PBE or IBBQ?

Over the past year, PBE had a volatility of 19.83%, while IBBQ experienced 21.05%.

Which ETF is bigger: PBE or IBBQ?

As of April 24, 2026, PBE holds $249.88 M in assets under management (AUM), while IBBQ manages $66.29 M.

What sectors do the PBE and IBBQ ETFs invest in?

PBE leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the PBE ETF and IBBQ ETF?

PBE top holdings include UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS. IBBQ holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.

PBEvsIBBQETF Comparison

Invesco Dynamic Biotechnology & Genome ETF

Invesco Nasdaq Biotechnology ETF

PBE vs IBBQ performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the PBE and IBBQ ETFs performed in 2026?

As of April 24, 2026, PBE is down -2.66% year-to-date (YTD), while IBBQ has returned 3.49%. That puts IBBQ better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or IBBQ?

Year-to-date, the PBE ETF saw -$2M in flows, compared to +$290K for IBBQ.

Which ETF is more volatile: PBE or IBBQ?

Over the past year, PBE had a volatility of 19.83%, while IBBQ experienced 21.05%.

Which ETF is bigger: PBE or IBBQ?

As of April 24, 2026, PBE holds $249.88 M in assets under management (AUM), while IBBQ manages $66.29 M.

What sectors do the PBE and IBBQ ETFs invest in?

PBE leans toward sectors like Health Care. Meanwhile, IBBQ focuses on Health Care.

What are the top holdings of the PBE ETF and IBBQ ETF?

PBE top holdings include UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS. IBBQ holds in its top three: GILEAD SCIENCES, AMGEN-T and VERTEX PHARMACEUTICALS.

Which ETF is more diversified: PBE or IBBQ?

PBE holds 30 securities with 63.66% of its assets in the top 15. IBBQ has 256 securities and a top 15 weight of 51.37%.

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