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PBEvsHTECETF Comparison

ETF 1

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

+4.79%

Full PBE fund page

VS

ETF 2

HTEC

Robo Global Healthcare Technology and Innovation ETF

This fund is part of

Multiple Trends

+2.34%

Full HTEC fund page

Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the BioTech & Genomics segment. Robo Global Healthcare Technology and Innovation ETF (HTEC) is part of the Multiple Trends segment. PBE's top 1 sector exposures are Healthcare. In contrast, HTEC's top sector exposures are Healthcare, Consumer Non-Cyclicals and Business Services. PBE is less expensive with a Total Expense Ratio (TER) of 0.59%, versus 0.8% for HTEC. PBE is up 24.01% year-to-date (YTD) with +$113M in YTD flows. HTEC performs better with 27.36% YTD performance, and +$41M in YTD flows. Run a side-by-side ETF comparison of PBE and HTEC below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PBE vs HTEC performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 10/27/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	PBE HTEC	+3.48%+2.13%	+12.22%+19.57%	+24.01%+27.36%	+38.47%+36.59%	+95.94%+105.72%	+38.86%-0.81%
Flows	PBE HTEC	-$947K+$34M	+$111M+$23M	+$113M+$41M	+$115M+$41M	+$62M+$10M	+$65M-$68M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	PBE HTEC	+21.55%+23.03%	+20.01%+21.26%	+20.60%+20.94%	+22.69%+24.28%
Max drawdown	PBE HTEC	-5.97%-6.70%	-11.70%-16.84%	-22.21%-22.68%	-32.63%-54.51%
Max drawdown duration	PBE HTEC	46d27d	166d160d	324d237d	1468d1819d

Trading data

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	PBE	HTEC
Last sale 10/28/2026 at 1:30 PM	$101.87	$46.01
Previous close 10/27/2026	$100.74	$45.21
Consolidated volume 10/27/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of September 30, 2026

1-year trailing difference

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	PBE	HTEC
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 10/28/2026 at 1:30 PM

Live

Closed

	PBE	HTEC
Last price	$101.87	$46.01
1D performance	+1.12%	+1.77%
AuM	$438.13 M	$112.88 M
E/R	0.59%	0.8%

Characteristics

	PBE	HTEC
Management strategy	Passive	Passive
Provider	Invesco	ROBO Global ETFs
Benchmark	Dynamic Biotech & Genome Intellidex Index	ROBO Global Healthcare Technology and Innovation
N° of holdings	30	63
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 23, 2005	June 25, 2019
ESG	No	Yes

More PBE data on Trackinsight

More HTEC data on Trackinsight

Exposure

Countries

PBE

USA

97.22%

Other

2.78%

HTEC

USA

77.08%

Other

22.92%

Sectors

PBE

Healthcare

100%

Other

0%

HTEC

Healthcare

95.03%

Other

4.97%

Diversification

PBE

Total weight of top 15 holdings out of 15

63.67%

HTEC

Total weight of top 15 holdings out of 15

33.84%

Top 15 holdings

Data as of August 31, 2026

PBE

CareDx, Inc.

5.49%

Amgen, Inc.

5.38%

Regeneron Pharmaceuticals, Inc.

5.26%

Vertex Pharmaceuticals, Inc.

5.21%

Royalty Pharma Plc

4.76%

Biogen, Inc.

4.75%

Gilead Sciences, Inc.

4.61%

United Therapeutics Corp.

3.77%

Omeros Corp.

3.73%

Repligen Corp.

3.57%

Illumina, Inc.

3.54%

Halozyme Therapeutics, Inc.

3.51%

Bio-Techne Corp.

3.41%

Protagonist Therapeutics, Inc.

3.37%

Alnylam Pharmaceuticals, Inc.

3.31%

HTEC

Moderna, Inc.

3.43%

Twist Bioscience Corp.

3.06%

CareDx, Inc.

2.78%

Natera, Inc.

2.43%

Tempus AI, Inc.

2.12%

Thermo Fisher Scientific, Inc.

2.12%

IQVIA Holdings, Inc.

2.11%

Adaptive Biotechnologies Corp.

2.11%

Guardant Health, Inc.

2.06%

Vertex Pharmaceuticals, Inc.

1.98%

Medpace Holdings, Inc.

1.97%

Illumina, Inc.

1.96%

Axogen, Inc.

1.93%

Charles River Laboratories International, Inc.

1.92%

Regeneron Pharmaceuticals, Inc.

1.87%

Frequently asked questions about PBE and HTEC

How have the PBE and HTEC ETFs performed in 2026?

As of October 27, 2026, PBE is up 24.01% year-to-date (YTD), while HTEC has returned 27.36%. That puts HTEC better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or HTEC?

Year-to-date, the PBE ETF saw +$113M in flows, compared to +$41M for HTEC.

Which ETF is more volatile: PBE or HTEC?

Over the past year, PBE had a volatility of 20.01%, while HTEC experienced 21.26%.

Which ETF is bigger: PBE or HTEC?

As of October 27, 2026, PBE holds $438.13 M in assets under management (AUM), while HTEC manages $112.88 M.

What sectors do the PBE and HTEC ETFs invest in?

PBE leans toward sectors like Healthcare. Meanwhile, HTEC focuses on Healthcare.

What are the top holdings of the PBE ETF and HTEC ETF?

PBE top holdings include CareDx, Inc., Amgen, Inc. and Regeneron Pharmaceuticals, Inc.. HTEC holds in its top three: Moderna, Inc., Twist Bioscience Corp. and CareDx, Inc..

Which ETF is more diversified: PBE or HTEC?

PBE holds 30 securities with 63.67% of its assets in the top 15. HTEC has 63 securities and a top 15 weight of 33.84%.

Biggest potential ETF theme - Innovation

October 13, 2022

HTEC

PBEvsHTECETF Comparison

Invesco Dynamic Biotechnology & Genome ETF

Robo Global Healthcare Technology and Innovation ETF

PBE vs HTEC performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the PBE and HTEC ETFs performed in 2026?

As of October 27, 2026, PBE is up 24.01% year-to-date (YTD), while HTEC has returned 27.36%. That puts HTEC better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or HTEC?

Year-to-date, the PBE ETF saw +$113M in flows, compared to +$41M for HTEC.

Which ETF is more volatile: PBE or HTEC?

Over the past year, PBE had a volatility of 20.01%, while HTEC experienced 21.26%.

Which ETF is bigger: PBE or HTEC?

As of October 27, 2026, PBE holds $438.13 M in assets under management (AUM), while HTEC manages $112.88 M.

What sectors do the PBE and HTEC ETFs invest in?

PBE leans toward sectors like Healthcare. Meanwhile, HTEC focuses on Healthcare.

What are the top holdings of the PBE ETF and HTEC ETF?

PBE top holdings include CareDx, Inc., Amgen, Inc. and Regeneron Pharmaceuticals, Inc.. HTEC holds in its top three: Moderna, Inc., Twist Bioscience Corp. and CareDx, Inc..

Which ETF is more diversified: PBE or HTEC?

PBE holds 30 securities with 63.67% of its assets in the top 15. HTEC has 63 securities and a top 15 weight of 33.84%.

Biggest potential ETF theme - Innovation

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