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PBEvsGNOMETF Comparison

ETF 1

PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of

BioTech & Genomics

-0.67%

Full PBE fund page

VS

ETF 2

GNOM

Global X Genomics & Biotechnology ETF - USD

This fund is part of

BioTech & Genomics

-0.67%

Full GNOM fund page

Invesco Dynamic Biotechnology & Genome ETF (PBE) and Global X Genomics & Biotechnology ETF - USD (GNOM) belong to the same industry segment: BioTech & Genomics. Both ETFs have the same top 3 sector exposures: and Health Care. PBE is more expensive with a Total Expense Ratio (TER) of 0.58%, versus 0.5% for GNOM. PBE is down -2.66% year-to-date (YTD) with -$2M in YTD flows. GNOM performs better with 0.74% YTD performance, and -$602K in YTD flows. Run a side-by-side ETF comparison of PBE and GNOM below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PBE vs GNOM performance and flow charts

Performance

Cumulative Flows

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Data Services

Historic performance and flows

Data as of 04/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	PBE GNOM	+4.27%+7.67%	-3.98%-7.03%	-2.66%+0.74%	+32.11%+41.51%	+28.24%-6.56%	+3.38%-50.60%
Flows	PBE GNOM	+$2M-$829K	-$6M+$1M	-$2M-$602K	-$30M-$14M	-$58M-$120M	-$43M+$1M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	PBE GNOM	+19.57%+28.47%	+19.83%+27.16%	+20.15%+28.79%	+22.54%+33.22%
Max drawdown	PBE GNOM	-9.36%-16.08%	-11.70%-18.16%	-22.21%-46.50%	-34.74%-72.17%
Max drawdown duration	PBE GNOM	75d88d	107d92d	324d1075d	1540d1758d

Trading data

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	PBE	GNOM
Last sale 4/27/2026 at 1:30 PM	$79.93	$45.55
Previous close 04/24/2026	$79.82	$45.97
Consolidated volume 04/24/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of March 31, 2026

1-year trailing difference

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	PBE	GNOM
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 4/27/2026 at 1:30 PM

Live

Closed

	PBE	GNOM
Last price	$79.93	$45.55
1D performance	+0.14%	-0.92%
AuM	$249.88 M	$51.60 M
E/R	0.58%	0.5%

Characteristics

	PBE	GNOM
Management strategy	Passive	Passive
Provider	Invesco	Global X
Benchmark	Dynamic Biotech & Genome Intellidex Index	Solactive Genomics Index
N° of holdings	30	45
Asset class	Equities	Equities
Trailing 12m distribution yield	Join	Join
Inception date	June 23, 2005	April 5, 2019
ESG	No	No

More PBE data on Trackinsight

More GNOM data on Trackinsight

Exposure

Countries

PBE

USA

92.18%

Other

7.82%

GNOM

USA

87.57%

Other

12.43%

Sectors

PBE

Health Care

97.59%

Other

2.41%

GNOM

Health Care

88.49%

Other

11.51%

Diversification

PBE

Total weight of top 15 holdings out of 15

63.66%

GNOM

Total weight of top 15 holdings out of 15

66.21%

Top 15 holdings

Data as of March 31, 2026

PBE

UTD THERAPEUT

6.05%

ILLUMINA

5.24%

REGENERON PHARMACEUTICALS

5.23%

ALNYLAM PHARMACEUTICALS

5.22%

BIOGEN INC

5.16%

AMGEN-T

4.99%

GILEAD SCIENCES

4.98%

INCYTE

4.89%

BIOCRYST PHARMACEUTICALS

3.66%

PROTAGONIST THERAPEUTICS INC

3.38%

TG THERAPEUTICS

3.11%

ROYALTY PHARMA

3.05%

NEUROCRINE BIOSCIENCES

2.93%

CATALYST PHARMACEUTICALS INC

2.89%

PTC THERAPEUTI/D

2.86%

GNOM

MODERNA INC

8.48%

ARROWHEAD PHARMACEUTICALS INC

6.21%

US74006W2070

6.13%

ILLUMINA

5.52%

GUARDANT HEALTH INC

5.18%

VERTEX PHARMACEUTICALS

4.61%

BIOMARIN PHARMACEUTICAL

4.59%

NATERA

4.21%

BIO-TECHNE CORP

3.64%

BIONTECH SE ADR

3.58%

CRISPR THERAPEUTICS

3.08%

BRISTOL-MYERS SQUIBB

3.05%

ALNYLAM PHARMACEUTICALS

2.85%

TWIST BIOSCIENCE CORP

2.54%

ASTRAZENECA

2.53%

Frequently asked questions about PBE and GNOM

How have the PBE and GNOM ETFs performed in 2026?

As of April 24, 2026, PBE is down -2.66% year-to-date (YTD), while GNOM has returned 0.74%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or GNOM?

Year-to-date, the PBE ETF saw -$2M in flows, compared to -$602K for GNOM.

Which ETF is more volatile: PBE or GNOM?

Over the past year, PBE had a volatility of 19.83%, while GNOM experienced 27.16%.

Which ETF is bigger: PBE or GNOM?

As of April 24, 2026, PBE holds $249.88 M in assets under management (AUM), while GNOM manages $51.60 M.

What sectors do the PBE and GNOM ETFs invest in?

PBE leans toward sectors like Health Care. Meanwhile, GNOM focuses on Health Care.

What are the top holdings of the PBE ETF and GNOM ETF?

PBE top holdings include UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS. GNOM holds in its top three: MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070.

PBEvsGNOMETF Comparison

Invesco Dynamic Biotechnology & Genome ETF

Global X Genomics & Biotechnology ETF - USD

PBE vs GNOM performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the PBE and GNOM ETFs performed in 2026?

As of April 24, 2026, PBE is down -2.66% year-to-date (YTD), while GNOM has returned 0.74%. That puts GNOM better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or GNOM?

Year-to-date, the PBE ETF saw -$2M in flows, compared to -$602K for GNOM.

Which ETF is more volatile: PBE or GNOM?

Over the past year, PBE had a volatility of 19.83%, while GNOM experienced 27.16%.

Which ETF is bigger: PBE or GNOM?

As of April 24, 2026, PBE holds $249.88 M in assets under management (AUM), while GNOM manages $51.60 M.

What sectors do the PBE and GNOM ETFs invest in?

PBE leans toward sectors like Health Care. Meanwhile, GNOM focuses on Health Care.

What are the top holdings of the PBE ETF and GNOM ETF?

PBE top holdings include UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS. GNOM holds in its top three: MODERNA INC, ARROWHEAD PHARMACEUTICALS INC and US74006W2070.

Which ETF is more diversified: PBE or GNOM?

PBE holds 30 securities with 63.66% of its assets in the top 15. GNOM has 47 securities and a top 15 weight of 66.21%.

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