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PBEvsFXHETF Comparison

ETF 1
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
-0.67%
VS
ETF 2
FXH

First Trust Health Care AlphaDEX Fund ETF

This fund is part of
US Health Care
-1.08%

Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the BioTech & Genomics segment. First Trust Health Care AlphaDEX Fund ETF (FXH) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Health Care. PBE is less expensive with a Total Expense Ratio (TER) of 0.58%, versus 0.61% for FXH. PBE is down -2.66% year-to-date (YTD) with -$2M in YTD flows. FXH performs better with -0.82% YTD performance, and -$61M in YTD flows. Run a side-by-side ETF comparison of PBE and FXH below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PBE vs FXH performance and flow charts

Performance

-2.00.02.04.06.08.0%Mar 24Mar 31Apr 8Apr 15Apr 22

Cumulative Flows

-10 M-8 M-6 M-4 M-2 M0 M2 MMar 24Mar 31Apr 8Apr 15Apr 22

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 04/24/2026
1M3MYTD1Y3Y5Y
Perf.
PBE
FXH
+4.27%+6.43%
-3.98%-4.04%
-2.66%-0.82%
+32.11%+14.86%
+28.24%+3.56%
+3.38%-1.76%
Flows
PBE
FXH
+$2M-$11M
-$6M-$67M
-$2M-$61M
-$30M-$123M
-$58M-$719M
-$43M-$505M
Volatility and drawdown
3M1Y3Y5Y
Volatility
PBE
FXH
+19.57%+17.12%
+19.83%+16.17%
+20.15%+15.26%
+22.54%+16.67%
Max drawdown
PBE
FXH
-9.36%-10.81%
-11.70%-12.07%
-22.21%-18.39%
-34.74%-29.40%
Max drawdown duration
PBE
FXH
75d88d
107d107d
324d464d
1540d1691d
Trading data

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PBE
FXH
Last sale
4/27/2026 at 1:30 PM
$79.93
$113.62
Previous close
04/24/2026
$79.82
$112.52
Consolidated volume
04/24/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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PBE
FXH
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
PBE
FXH
Last price
$79.93
$113.62
1D performance
+0.14%
+0.97%
AuM$249.88 M$867.10 M
E/R0.58%0.61%
Characteristics
PBE
FXH
Management strategyPassivePassive
ProviderInvescoFirst Trust
BenchmarkDynamic Biotech & Genome Intellidex IndexStrataQuant Health Care Index
N° of holdings3071
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateJune 23, 2005May 8, 2007
ESGNoNo
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Exposure

Countries

PBE
USA
92.18%
Other
7.82%
FXH
USA
95.47%
Other
4.53%

Sectors

PBE
Health Care
97.59%
Other
2.41%
FXH
Health Care
93.76%
Other
6.24%

Diversification

PBE

Total weight of top 15 holdings out of 15

63.66%
FXH

Total weight of top 15 holdings out of 15

35.37%

Top 15 holdings

Data as of March 31, 2026
PBE
UTD THERAPEUT
6.05%
ILLUMINA
5.24%
REGENERON PHARMACEUTICALS
5.23%
ALNYLAM PHARMACEUTICALS
5.22%
BIOGEN INC
5.16%
AMGEN-T
4.99%
GILEAD SCIENCES
4.98%
INCYTE
4.89%
BIOCRYST PHARMACEUTICALS
3.66%
PROTAGONIST THERAPEUTICS INC
3.38%
TG THERAPEUTICS
3.11%
ROYALTY PHARMA
3.05%
NEUROCRINE BIOSCIENCES
2.93%
CATALYST PHARMACEUTICALS INC
2.89%
PTC THERAPEUTI/D
2.86%
FXH
ACADIA HEALTHCARE COMPANY
3.83%
APELLIS PHARMACEUTICALS
2.95%
PFIZER
2.63%
BIOGEN INC
2.40%
CARDINAL HEALTH
2.37%
HCA HEALTHCARE
2.33%
INCYTE
2.19%
IONIS PHARMACEUTICALS INC
2.18%
INSMED
2.17%
UTD THERAPEUT
2.15%
MERCK & CO INC
2.11%
LILLY
2.04%
NATERA
2.04%
MEDPACE HOLDINGS INC
2.00%
AMGEN-T
1.98%
Frequently asked questions about PBE and FXH

How have the PBE and FXH ETFs performed in 2026?

As of April 24, 2026, PBE is down -2.66% year-to-date (YTD), while FXH has lost -0.82%. That puts FXH better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or FXH?

Year-to-date, the PBE ETF saw -$2M in flows, compared to -$61M for FXH.

Which ETF is more volatile: PBE or FXH?

Over the past year, PBE had a volatility of 19.83%, while FXH experienced 16.17%.

Which ETF is bigger: PBE or FXH?

As of April 24, 2026, PBE holds $249.88 M in assets under management (AUM), while FXH manages $867.10 M.

What sectors do the PBE and FXH ETFs invest in?

PBE leans toward sectors like Health Care. Meanwhile, FXH focuses on Health Care.

What are the top holdings of the PBE ETF and FXH ETF?

PBE top holdings include UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS. FXH holds in its top three: ACADIA HEALTHCARE COMPANY, APELLIS PHARMACEUTICALS and PFIZER.

Which ETF is more diversified: PBE or FXH?

PBE holds 30 securities with 63.66% of its assets in the top 15. FXH has 75 securities and a top 15 weight of 35.37%.

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