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PBEvsEKGETF Comparison

ETF 1
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
-0.67%
VS
ETF 2
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
-0.51%

Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the BioTech & Genomics segment. First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) is part of the Healthcare Technology segment. Both ETFs have the same top 3 sector exposures: and Health Care. PBE is less expensive with a Total Expense Ratio (TER) of 0.58%, versus 0.65% for EKG. PBE is down -2.66% year-to-date (YTD) with -$2M in YTD flows. EKG performs worse with -11.32% YTD performance, and - in YTD flows. Run a side-by-side ETF comparison of PBE and EKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PBE vs EKG performance and flow charts

Performance

-6.0-4.0-2.00.02.04.06.0%Mar 24Mar 31Apr 8Apr 15Apr 22

Cumulative Flows

-500,0000500,0001,000,0001,500,000Mar 24Mar 31Apr 8Apr 15Apr 22

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 04/24/2026
1M3MYTD1Y3Y5Y
Perf.
PBE
EKG
+4.27%+1.63%
-3.98%-14.29%
-2.66%-11.32%
+32.11%+6.73%
+28.24%-6.06%
+3.38%n/a
Flows
PBE
EKG
+$2M-
-$6M-
-$2M-
-$30M-$25K
-$58M+$1M
-$43M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
PBE
EKG
+19.57%+25.81%
+19.83%+21.14%
+20.15%+22.97%
+22.54%n/a
Max drawdown
PBE
EKG
-9.36%-19.93%
-11.70%-21.99%
-22.21%-34.97%
-34.74%n/a
Max drawdown duration
PBE
EKG
75d88d
107d107d
324d563d
1540dn/a
Trading data

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PBE
EKG
Last sale
4/27/2026 at 1:30 PM
$79.93
$16.81
Previous close
04/24/2026
$79.82
$16.85
Consolidated volume
04/24/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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PBE
EKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/27/2026 at 1:30 PM
Live
Closed
PBE
EKG
Last price
$79.93
$16.81
1D performance
+0.14%
-0.24%
AuM$249.88 M$2.53 M
E/R0.58%0.65%
Characteristics
PBE
EKG
Management strategyPassivePassive
ProviderInvescoFirst Trust
BenchmarkDynamic Biotech & Genome Intellidex IndexNasdaq Lux Health Tech Index
N° of holdings3033
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateJune 23, 2005March 22, 2022
ESGNoNo
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Exposure

Countries

PBE
USA
92.18%
Other
7.82%
EKG
USA
94.35%
Other
5.65%

Sectors

PBE
Health Care
97.59%
Other
2.41%
EKG
Health Care
86.01%
Other
13.99%
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Diversification

PBE

Total weight of top 15 holdings out of 15

63.66%
EKG

Total weight of top 15 holdings out of 15

74.16%

Top 15 holdings

Data as of March 31, 2026
PBE
UTD THERAPEUT
6.05%
ILLUMINA
5.24%
REGENERON PHARMACEUTICALS
5.23%
ALNYLAM PHARMACEUTICALS
5.22%
BIOGEN INC
5.16%
AMGEN-T
4.99%
GILEAD SCIENCES
4.98%
INCYTE
4.89%
BIOCRYST PHARMACEUTICALS
3.66%
PROTAGONIST THERAPEUTICS INC
3.38%
TG THERAPEUTICS
3.11%
ROYALTY PHARMA
3.05%
NEUROCRINE BIOSCIENCES
2.93%
CATALYST PHARMACEUTICALS INC
2.89%
PTC THERAPEUTI/D
2.86%
EKG
IQVIA HOLDINGS INC
8.48%
VEEVA SYSTEMS IN
8.34%
INTUITIVE SURGICAL
8.11%
RESMED
7.65%
DEXCOM
7.47%
NATERA
4.30%
GUARDANT HEALTH INC
4.27%
ILLUMINA
4.14%
GLOBUS MEDICAL
4.04%
ALIGN TECHNOLOGY
4.00%
INSULET
3.69%
US88023B1035
3.45%
IRHYTHM TECHNOLOGIES
2.14%
HIMS & HERS HEALTH INC
2.13%
OSCAR HEALTH
1.95%
Frequently asked questions about PBE and EKG

How have the PBE and EKG ETFs performed in 2026?

As of April 24, 2026, PBE is down -2.66% year-to-date (YTD), while EKG has lost -11.32%. That puts PBE better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or EKG?

Year-to-date, the PBE ETF saw -$2M in flows, compared to - for EKG.

Which ETF is more volatile: PBE or EKG?

Over the past year, PBE had a volatility of 19.83%, while EKG experienced 21.14%.

Which ETF is bigger: PBE or EKG?

As of April 24, 2026, PBE holds $249.88 M in assets under management (AUM), while EKG manages $2.53 M.

What sectors do the PBE and EKG ETFs invest in?

PBE leans toward sectors like Health Care. Meanwhile, EKG focuses on Health Care.

What are the top holdings of the PBE ETF and EKG ETF?

PBE top holdings include UTD THERAPEUT, ILLUMINA and REGENERON PHARMACEUTICALS. EKG holds in its top three: IQVIA HOLDINGS INC, VEEVA SYSTEMS IN and INTUITIVE SURGICAL.

Which ETF is more diversified: PBE or EKG?

PBE holds 30 securities with 63.66% of its assets in the top 15. EKG has 36 securities and a top 15 weight of 74.16%.

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