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PBEvsEKGETF Comparison

ETF 1
PBE

Invesco Dynamic Biotechnology & Genome ETF

This fund is part of
BioTech & Genomics
+0.33%
VS
ETF 2
EKG

First Trust Nasdaq Lux Digital Health Solutions ETF

This fund is part of
Healthcare Technology
+0.38%

Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the BioTech & Genomics segment. First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) is part of the Healthcare Technology segment. Both ETFs have the same top 1 sector exposures: Healthcare. PBE is less expensive with a Total Expense Ratio (TER) of 0.59%, versus 0.65% for EKG. PBE is up 14.59% year-to-date (YTD) with +$114M in YTD flows. EKG performs worse with 11.43% YTD performance, and +$963K in YTD flows. Run a side-by-side ETF comparison of PBE and EKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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PBE vs EKG performance and flow charts

Performance

0.02.04.06.0%Aug 10Aug 17Aug 24Aug 31Sep 8

Cumulative Flows

020,000,00040,000,00060,000,00080,000,000100,000,000Aug 10Aug 17Aug 24Aug 31Sep 8

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Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 09/10/2026
1M3MYTD1Y3Y5Y
Perf.
PBE
EKG
-0.70%+0.39%
+12.83%+21.17%
+14.59%+11.43%
+35.63%+22.85%
+57.51%+36.04%
+23.66%n/a
Flows
PBE
EKG
+$44M-
+$117M+$963K
+$114M+$963K
+$113M+$963K
+$62M+$2M
+$64M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
PBE
EKG
+19.58%+26.19%
+19.33%+23.51%
+20.48%+23.84%
+22.57%n/a
Max drawdown
PBE
EKG
-5.73%-7.45%
-11.70%-22.11%
-22.21%-24.32%
-33.32%n/a
Max drawdown duration
PBE
EKG
7d28d
166d208d
324d264d
1509dn/a
Trading data

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PBE
EKG
Last sale
9/11/2026 at 1:30 PM
$92.91
$21.35
Previous close
09/10/2026
$93.03
$21.17
Consolidated volume
09/10/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of August 31, 2026
1-year trailing difference

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PBE
EKG
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 9/11/2026 at 1:30 PM
Live
Closed
PBE
EKG
Last price
$92.91
$21.35
1D performance
-0.13%
+0.83%
AuM$405.87 M$4.23 M
E/R0.59%0.65%
Characteristics
PBE
EKG
Management strategyPassivePassive
ProviderInvescoFirst Trust
BenchmarkDynamic Biotech & Genome Intellidex IndexNasdaq Lux Health Tech Index
N° of holdings3037
Asset classEquitiesEquities
Trailing 12m distribution yield
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Inception dateJune 23, 2005March 22, 2022
ESGNoNo
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Exposure

Countries

PBE
USA
97.13%
Other
2.87%
EKG
USA
95.72%
Other
4.28%

Sectors

PBE
Healthcare
100%
Other
0%
EKG
Healthcare
98.67%
Other
1.33%
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Diversification

PBE

Total weight of top 15 holdings out of 15

61.32%
EKG

Total weight of top 15 holdings out of 15

74.55%

Top 15 holdings

Data as of July 31, 2026
PBE
Amgen, Inc.
5.16%
Vertex Pharmaceuticals, Inc.
4.96%
Royalty Pharma Plc
4.91%
Regeneron Pharmaceuticals, Inc.
4.90%
Biogen, Inc.
4.85%
Gilead Sciences, Inc.
4.44%
Alnylam Pharmaceuticals, Inc.
4.34%
United Therapeutics Corp.
4.06%
CareDx, Inc.
4.01%
Bio-Techne Corp.
3.66%
Illumina, Inc.
3.27%
Vericel Corp.
3.25%
Protagonist Therapeutics, Inc.
3.24%
Incyte Corp.
3.19%
Veracyte, Inc.
3.07%
EKG
IQVIA Holdings, Inc.
9.37%
Veeva Systems, Inc.
9.01%
DexCom, Inc.
8.04%
Guardant Health, Inc.
5.85%
ResMed, Inc.
5.83%
Illumina, Inc.
5.19%
Natera, Inc.
5.11%
Intuitive Surgical, Inc.
4.87%
Oscar Health, Inc.
3.90%
Tempus AI, Inc.
3.64%
QIAGEN NV
2.95%
Globus Medical, Inc.
2.94%
Align Technology, Inc.
2.74%
10X Genomics, Inc.
2.57%
Hims & Hers Health, Inc.
2.54%
Frequently asked questions about PBE and EKG

How have the PBE and EKG ETFs performed in 2026?

As of September 10, 2026, PBE is up 14.59% year-to-date (YTD), while EKG has returned 11.43%. That puts PBE better performer ahead so far this year.

Which ETF is attracting more investor money: PBE or EKG?

Year-to-date, the PBE ETF saw +$114M in flows, compared to +$963K for EKG.

Which ETF is more volatile: PBE or EKG?

Over the past year, PBE had a volatility of 19.33%, while EKG experienced 23.51%.

Which ETF is bigger: PBE or EKG?

As of September 10, 2026, PBE holds $405.87 M in assets under management (AUM), while EKG manages $4.23 M.

What sectors do the PBE and EKG ETFs invest in?

PBE leans toward sectors like Healthcare. Meanwhile, EKG focuses on Healthcare.

What are the top holdings of the PBE ETF and EKG ETF?

PBE top holdings include Amgen, Inc., Vertex Pharmaceuticals, Inc. and Royalty Pharma Plc. EKG holds in its top three: IQVIA Holdings, Inc., Veeva Systems, Inc. and DexCom, Inc..

Which ETF is more diversified: PBE or EKG?

PBE holds 30 securities with 61.32% of its assets in the top 15. EKG has 37 securities and a top 15 weight of 74.55%.

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