PBEvsEKGETF Comparison
VS
ETF 2
EKG
First Trust Nasdaq Lux Digital Health Solutions ETF
This fund is part of
Healthcare Technology
+0.76%
Invesco Dynamic Biotechnology & Genome ETF (PBE) belongs to the BioTech & Genomics segment. First Trust Nasdaq Lux Digital Health Solutions ETF (EKG) is part of the Healthcare Technology segment. Both ETFs have the same top 1 sector exposures: Healthcare. PBE is less expensive with a Total Expense Ratio (TER) of 0.59%, versus 0.65% for EKG. PBE is up 24.01% year-to-date (YTD) with +$113M in YTD flows. EKG performs better with 28.2% YTD performance, and +$6M in YTD flows. Run a side-by-side ETF comparison of PBE and EKG below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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PBE vs EKG performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 10/27/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | PBE EKG | +3.48%+2.94% | +12.22%+29.14% | +24.01%+28.20% | +38.47%+31.04% | +95.94%+99.67% | +38.86%n/a |
| Flows | PBE EKG | -$947K+$5M | +$111M+$5M | +$113M+$6M | +$115M+$6M | +$62M+$7M | +$65M- |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | PBE EKG | +21.55%+25.88% | +20.01%+24.40% | +20.60%+23.86% | +22.69%n/a |
| Max drawdown | PBE EKG | -5.97%-5.73% | -11.70%-22.11% | -22.21%-24.32% | -32.63%n/a |
| Max drawdown duration | PBE EKG | 46d21d | 166d208d | 324d264d | 1468dn/a |
Trading data
PBE | EKG | |
Last sale 10/28/2026 at 1:30 PM | $101.87 | $24.82 |
| Previous close 10/27/2026 | $100.74 | $24.35 |
| Consolidated volume 10/27/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of September 30, 2026
1-year trailing difference
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PBE | EKG | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 10/28/2026 at 1:30 PM
Live
Closed
PBE | EKG | |
|---|---|---|
| Last price | $101.87 | $24.82 |
| 1D performance | +1.12% | +1.93% |
| AuM | $438.13 M | $9.74 M |
| E/R | 0.59% | 0.65% |
Characteristics
PBE | EKG | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | Invesco | First Trust |
| Benchmark | Dynamic Biotech & Genome Intellidex Index | Nasdaq Lux Health Tech Index |
| N° of holdings | 30 | 37 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 23, 2005 | March 22, 2022 |
| ESG | No | No |
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Exposure
Countries
PBE
USA
97.22%
Other
2.78%
EKG
USA
95.68%
Other
4.32%
Sectors
PBE
Healthcare
100%
Other
0%
EKG
Healthcare
98.54%
Other
1.46%
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Diversification
PBE
Total weight of top 15 holdings out of 15
63.67%
EKG
Total weight of top 15 holdings out of 15
74.46%
Top 15 holdings
Data as of August 31, 2026
PBE
CareDx, Inc.
5.49%
Amgen, Inc.
5.38%
Regeneron Pharmaceuticals, Inc.
5.26%
Vertex Pharmaceuticals, Inc.
5.21%
Royalty Pharma Plc
4.76%
Biogen, Inc.
4.75%
Gilead Sciences, Inc.
4.61%
United Therapeutics Corp.
3.77%
Omeros Corp.
3.73%
Repligen Corp.
3.57%
Illumina, Inc.
3.54%
Halozyme Therapeutics, Inc.
3.51%
Bio-Techne Corp.
3.41%
Protagonist Therapeutics, Inc.
3.37%
Alnylam Pharmaceuticals, Inc.
3.31%
EKG
Veeva Systems, Inc.
10.09%
IQVIA Holdings, Inc.
9.50%
DexCom, Inc.
8.07%
ResMed, Inc.
5.93%
Guardant Health, Inc.
5.76%
Illumina, Inc.
5.07%
Natera, Inc.
5.07%
Intuitive Surgical, Inc.
4.82%
Oscar Health, Inc.
3.71%
Tempus AI, Inc.
3.42%
QIAGEN NV
2.86%
Globus Medical, Inc.
2.77%
Align Technology, Inc.
2.68%
10X Genomics, Inc.
2.42%
Twist Bioscience Corp.
2.29%
Frequently asked questions about PBE and EKG
How have the PBE and EKG ETFs performed in 2026?
As of October 27, 2026, PBE is up 24.01% year-to-date (YTD), while EKG has returned 28.2%. That puts EKG better performer ahead so far this year.
Which ETF is attracting more investor money: PBE or EKG?
Year-to-date, the PBE ETF saw +$113M in flows, compared to +$6M for EKG.
Which ETF is more volatile: PBE or EKG?
Over the past year, PBE had a volatility of 20.01%, while EKG experienced 24.4%.
Which ETF is bigger: PBE or EKG?
As of October 27, 2026, PBE holds $438.13 M in assets under management (AUM), while EKG manages $9.74 M.
What sectors do the PBE and EKG ETFs invest in?
PBE leans toward sectors like Healthcare. Meanwhile, EKG focuses on Healthcare.
What are the top holdings of the PBE ETF and EKG ETF?
PBE top holdings include CareDx, Inc., Amgen, Inc. and Regeneron Pharmaceuticals, Inc.. EKG holds in its top three: Veeva Systems, Inc., IQVIA Holdings, Inc. and DexCom, Inc..
Which ETF is more diversified: PBE or EKG?
PBE holds 30 securities with 63.67% of its assets in the top 15. EKG has 37 securities and a top 15 weight of 74.46%.
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