MDEVvsIDNAETF Comparison
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First Trust Indxx Medical Devices ETF (MDEV) belongs to the Healthcare Technology segment. iShares Genomics Immunology and Healthcare ETF (IDNA) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Healthcare. MDEV is more expensive with a Total Expense Ratio (TER) of 0.7%, versus 0.47% for IDNA. MDEV is down -3.05% year-to-date (YTD) with +$994K in YTD flows. IDNA performs better with 25.82% YTD performance, and +$29M in YTD flows. Run a side-by-side ETF comparison of MDEV and IDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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MDEV vs IDNA performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/30/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | MDEV IDNA | +6.20%-2.54% | +9.77%+11.88% | -3.05%+25.82% | -0.45%+52.00% | -2.20%+41.69% | -23.17%-31.23% |
| Flows | MDEV IDNA | +$994K+$7M | +$994K+$15M | +$994K+$29M | +$994K+$25M | +$767K+$5M | -$23M+$10M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | MDEV IDNA | +17.24%+24.73% | +16.50%+23.92% | +16.33%+24.16% | +19.16%+27.98% |
| Max drawdown | MDEV IDNA | -3.88%-8.02% | -18.07%-10.60% | -21.75%-29.33% | -42.16%-68.19% |
| Max drawdown duration | MDEV IDNA | 11d25d | 205d46d | 205d347d | 1787d1775d |
Trading data
MDEV | IDNA | |
Last sale 7/31/2026 at 1:30 PM | $20.24 | $32.33 |
| Previous close 07/30/2026 | $20.16 | $32.79 |
| Consolidated volume 07/30/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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MDEV | IDNA | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/31/2026 at 1:30 PM
Live
Closed
MDEV | IDNA | |
|---|---|---|
| Last price | $20.24 | $32.33 |
| 1D performance | +0.39% | -1.40% |
| AuM | $3.06 M | $193.55 M |
| E/R | 0.7% | 0.47% |
Characteristics
MDEV | IDNA | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | iShares |
| Benchmark | Indxx Global Medical Equipment Index | NYSE FactSet Global Genomics and Immuno Biopharma Index |
| N° of holdings | 47 | 48 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 23, 2021 | June 11, 2019 |
| ESG | No | No |
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Exposure
Countries
MDEV
USA
55.63%
Japan
7.86%
Other
36.51%
IDNA
USA
61.08%
Germany
8.29%
France
7.46%
Other
23.17%
Sectors
MDEV
Healthcare
95.26%
Other
4.74%
IDNA
Healthcare
99.73%
Other
0.27%
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Diversification
MDEV
Total weight of top 15 holdings out of 15
35.95%
IDNA
Total weight of top 15 holdings out of 15
59.79%
Top 15 holdings
Data as of June 30, 2026
MDEV
West Pharmaceutical Services, Inc.
2.88%
Demant A/S
2.76%
LivaNova Plc
2.67%
Baxter International, Inc.
2.57%
Revvity, Inc.
2.55%
WuXi AppTec Co., Ltd.
2.41%
Waters Corp.
2.40%
Edwards Lifesciences Corp.
2.40%
Agilent Technologies, Inc.
2.36%
Teleflex, Inc.
2.23%
DexCom, Inc.
2.18%
Bio-Rad Laboratories, Inc.
2.16%
Sonova Holding AG
2.13%
Align Technology, Inc.
2.13%
Sysmex Corp.
2.12%
IDNA
Twist Bioscience Corp.
5.18%
Moderna, Inc.
5.14%
Bayer AG
4.61%
Revolution Medicines, Inc.
4.37%
Genmab A/S
3.88%
Vertex Pharmaceuticals, Inc.
3.87%
Incyte Corp.
3.86%
Merck & Co., Inc.
3.71%
Ipsen SA
3.69%
BioNTech SE
3.68%
ImmunityBio, Inc.
3.60%
Exelixis, Inc.
3.60%
Takeda Pharmaceutical Co., Ltd.
3.59%
GSK Plc
3.53%
Roche Holding AG
3.49%
Frequently asked questions about MDEV and IDNA
How have the MDEV and IDNA ETFs performed in 2026?
As of July 30, 2026, MDEV is down -3.05% year-to-date (YTD), while IDNA has returned 25.82%. That puts IDNA better performer ahead so far this year.
Which ETF is attracting more investor money: MDEV or IDNA?
Year-to-date, the MDEV ETF saw +$994K in flows, compared to +$29M for IDNA.
Which ETF is more volatile: MDEV or IDNA?
Over the past year, MDEV had a volatility of 16.5%, while IDNA experienced 23.92%.
Which ETF is bigger: MDEV or IDNA?
As of July 30, 2026, MDEV holds $3.06 M in assets under management (AUM), while IDNA manages $193.55 M.
What sectors do the MDEV and IDNA ETFs invest in?
MDEV leans toward sectors like Healthcare. Meanwhile, IDNA focuses on Healthcare.
What are the top holdings of the MDEV ETF and IDNA ETF?
MDEV top holdings include West Pharmaceutical Services, Inc., Demant A/S and LivaNova Plc. IDNA holds in its top three: Twist Bioscience Corp., Moderna, Inc. and Bayer AG.
Which ETF is more diversified: MDEV or IDNA?
MDEV holds 47 securities with 35.95% of its assets in the top 15. IDNA has 48 securities and a top 15 weight of 59.79%.
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