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MDEVvsIDNAETF Comparison

ETF 1
MDEV

First Trust Indxx Medical Devices ETF

This fund is part of
Healthcare Technology
-0.67%
VS
ETF 2
IDNA

iShares Genomics Immunology and Healthcare ETF

This fund is part of
BioTech & Genomics
-5.05%

First Trust Indxx Medical Devices ETF (MDEV) belongs to the Healthcare Technology segment. iShares Genomics Immunology and Healthcare ETF (IDNA) is part of the BioTech & Genomics segment. MDEV's top 1 sector exposures are Healthcare. In contrast, IDNA's top sector exposures are Healthcare and Non-Corporate. MDEV is more expensive with a Total Expense Ratio (TER) of 0.7%, versus 0.47% for IDNA. MDEV is up 6.22% year-to-date (YTD) with +$994K in YTD flows. IDNA performs better with 63.63% YTD performance, and +$107M in YTD flows. Run a side-by-side ETF comparison of MDEV and IDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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MDEV vs IDNA performance and flow charts

Performance

-6.0-4.0-2.00.02.04.06.0%Sep 29Oct 6Oct 13Oct 20Oct 27

Cumulative Flows

0 M10 M20 M30 M40 MSep 29Oct 6Oct 13Oct 20Oct 27

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Historic performance and flows
Data as of 10/29/2026
1M3MYTD1Y3Y5Y
Perf.
MDEV
IDNA
+6.16%+0.60%
+9.81%+30.05%
+6.22%+63.63%
+7.94%+70.87%
+36.93%+148.49%
-15.18%-11.19%
Flows
MDEV
IDNA
-+$39M
-+$78M
+$994K+$107M
+$994K+$106M
+$767K+$84M
-$26M+$64M
Volatility and drawdown
3M1Y3Y5Y
Volatility
MDEV
IDNA
+14.15%+40.70%
+16.02%+29.28%
+16.23%+25.96%
+19.20%+28.86%
Max drawdown
MDEV
IDNA
-6.88%-8.56%
-18.07%-10.60%
-20.26%-29.33%
-39.56%-65.57%
Max drawdown duration
MDEV
IDNA
57d27d
288d46d
637d347d
1821d1822d
Trading data

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MDEV
IDNA
Last sale
10/30/2026 at 1:30 PM
$21.85
$42.76
Previous close
10/29/2026
$22.24
$42.99
Consolidated volume
10/29/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of September 30, 2026
1-year trailing difference

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MDEV
IDNA
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 10/30/2026 at 1:30 PM
Live
Closed
MDEV
IDNA
Last price
$21.85
$42.76
1D performance
-1.78%
-0.54%
AuM$3.35 M$334.91 M
E/R0.7%0.47%
Characteristics
MDEV
IDNA
Management strategyPassivePassive
ProviderFirst TrustiShares
BenchmarkIndxx Global Medical Equipment IndexNYSE FactSet Global Genomics and Immuno Biopharma Index
N° of holdings4748
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateJune 23, 2021June 11, 2019
ESGNoNo
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Exposure

Countries

MDEV
USA
55.12%
Japan
8.7%
Other
36.18%
IDNA
USA
66.57%
Other
33.43%

Sectors

MDEV
Healthcare
96.13%
Other
3.87%
IDNA
Healthcare
99.66%
Other
0.34%
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Diversification

MDEV

Total weight of top 15 holdings out of 15

39.6%
IDNA

Total weight of top 15 holdings out of 15

64.14%

Top 15 holdings

Data as of September 30, 2026
MDEV
Revvity, Inc.
3.17%
WuXi AppTec Co., Ltd.
3.17%
Demant A/S
2.90%
Agilent Technologies, Inc.
2.76%
West Pharmaceutical Services, Inc.
2.70%
Baxter International, Inc.
2.63%
Sysmex Corp.
2.61%
DexCom, Inc.
2.57%
Waters Corp.
2.53%
Thermo Fisher Scientific, Inc.
2.49%
Sonova Holding AG
2.48%
Olympus Corp.
2.48%
Bio-Rad Laboratories, Inc.
2.43%
Merit Medical Systems, Inc.
2.41%
LivaNova Plc
2.27%
IDNA
Moderna, Inc.
11.20%
Twist Bioscience Corp.
7.70%
Iovance Biotherapeutics, Inc.
4.98%
Genmab A/S
3.98%
Revolution Medicines, Inc.
3.79%
Bayer AG
3.60%
Merck & Co., Inc.
3.32%
Takeda Pharmaceutical Co., Ltd.
3.30%
Regeneron Pharmaceuticals, Inc.
3.29%
Incyte Corp.
3.27%
Caris Life Sciences, Inc.
3.25%
Vertex Pharmaceuticals, Inc.
3.23%
BioNTech SE
3.08%
ImmunityBio, Inc.
3.08%
Exelixis, Inc.
3.06%
Frequently asked questions about MDEV and IDNA

How have the MDEV and IDNA ETFs performed in 2026?

As of October 29, 2026, MDEV is up 6.22% year-to-date (YTD), while IDNA has returned 63.63%. That puts IDNA better performer ahead so far this year.

Which ETF is attracting more investor money: MDEV or IDNA?

Year-to-date, the MDEV ETF saw +$994K in flows, compared to +$107M for IDNA.

Which ETF is more volatile: MDEV or IDNA?

Over the past year, MDEV had a volatility of 16.02%, while IDNA experienced 29.28%.

Which ETF is bigger: MDEV or IDNA?

As of October 29, 2026, MDEV holds $3.35 M in assets under management (AUM), while IDNA manages $334.91 M.

What sectors do the MDEV and IDNA ETFs invest in?

MDEV leans toward sectors like Healthcare. Meanwhile, IDNA focuses on Healthcare.

What are the top holdings of the MDEV ETF and IDNA ETF?

MDEV top holdings include Revvity, Inc., WuXi AppTec Co., Ltd. and Demant A/S. IDNA holds in its top three: Moderna, Inc., Twist Bioscience Corp. and Iovance Biotherapeutics, Inc..

Which ETF is more diversified: MDEV or IDNA?

MDEV holds 47 securities with 39.6% of its assets in the top 15. IDNA has 48 securities and a top 15 weight of 64.14%.

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