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MDEVvsIDNAETF Comparison

ETF 1
MDEV

First Trust Indxx Medical Devices ETF

This fund is part of
Healthcare Technology
-0.08%
VS
ETF 2
IDNA

iShares Genomics Immunology and Healthcare ETF

This fund is part of
BioTech & Genomics
-0.14%

First Trust Indxx Medical Devices ETF (MDEV) belongs to the Healthcare Technology segment. iShares Genomics Immunology and Healthcare ETF (IDNA) is part of the BioTech & Genomics segment. Both ETFs have the same top 3 sector exposures: and Health Care. MDEV is more expensive with a Total Expense Ratio (TER) of 0.7%, versus 0.47% for IDNA. MDEV is down -10.01% year-to-date (YTD) with - in YTD flows. IDNA performs better with 13.02% YTD performance, and +$14M in YTD flows. Run a side-by-side ETF comparison of MDEV and IDNA below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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MDEV vs IDNA performance and flow charts

Performance

024681012%Mar 27Apr 6Apr 13Apr 20Apr 27

Cumulative Flows

0 M2 M4 M6 M8 MMar 27Apr 6Apr 13Apr 20Apr 27

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Historic performance and flows
Data as of 04/27/2026
1M3MYTD1Y3Y5Y
Perf.
MDEV
IDNA
+1.65%+5.94%
-11.11%-0.13%
-10.01%+13.02%
-5.11%+44.30%
-9.56%+31.26%
n/a-36.01%
Flows
MDEV
IDNA
-+$8M
-+$14M
-+$14M
+$0K+$7M
-$228K-$12M
-+$13M
Volatility and drawdown
3M1Y3Y5Y
Volatility
MDEV
IDNA
+16.63%+24.29%
+15.77%+23.78%
+15.86%+24.06%
n/a+27.94%
Max drawdown
MDEV
IDNA
-12.55%-10.60%
-14.75%-10.60%
-22.71%-30.61%
n/a-68.19%
Max drawdown duration
MDEV
IDNA
90d46d
111d46d
307d279d
n/a1681d
Trading data

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MDEV
IDNA
Last sale
4/28/2026 at 1:30 PM
$18.61
$28.89
Previous close
04/28/2026
$18.90
$29.39
Consolidated volume
04/28/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of March 31, 2026
1-year trailing difference

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MDEV
IDNA
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 4/28/2026 at 1:30 PM
Live
Closed
MDEV
IDNA
Last price
$18.61
$28.89
1D performance
-1.55%
-1.72%
AuM$1.89 M$161.27 M
E/R0.7%0.47%
Characteristics
MDEV
IDNA
Management strategyPassivePassive
ProviderFirst TrustiShares
BenchmarkIndxx Global Medical Equipment IndexNYSE FactSet Global Genomics and Immuno Biopharma Index
N° of holdings4741
Asset classEquitiesEquities
Trailing 12m distribution yield
Join
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Inception dateJune 23, 2021June 11, 2019
ESGNoNo
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Exposure

Countries

MDEV
USA
60.07%
Japan
7.84%
Other
32.09%
IDNA
USA
63.25%
France
8.84%
Other
27.9%

Sectors

MDEV
Health Care
93.19%
Other
6.81%
IDNA
Health Care
90.61%
Other
9.39%
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Diversification

MDEV

Total weight of top 15 holdings out of 15

37.53%
IDNA

Total weight of top 15 holdings out of 15

64.09%

Top 15 holdings

Data as of March 31, 2026
MDEV
GLOBUS MEDICAL
3.36%
ALIGN TECHNOLOGY
2.98%
PENUMBRA
2.74%
MASIMO
2.67%
HOYA
2.67%
WATERS
2.43%
HOLOGIC
2.42%
WUXI APPTEC CO LTD
2.39%
EDWARDS LIFESCIENCES
2.38%
INTUITIVE SURGICAL
2.33%
ALCON INC
2.27%
US2166485019
2.26%
FISHER PAYKEL
2.23%
US36266G1076
2.20%
METTLER TOLEDO
2.20%
IDNA
MODERNA INC
6.75%
ARCELLX
5.36%
IPSEN PROMESSES
4.79%
TAKEDA PHARMACEUTICAL
4.62%
REVOLUTION MEDICINES INC
4.49%
MERCK & CO INC
4.44%
BAYER AG
4.31%
GSK PLC
4.16%
REGENERON PHARMACEUTICALS
3.96%
CH1499059983
3.72%
VERTEX PHARMACEUTICALS
3.61%
EXELIXIS
3.56%
SANOFI SA
3.54%
BIONTECH SE ADR
3.40%
INCYTE
3.38%
Frequently asked questions about MDEV and IDNA

How have the MDEV and IDNA ETFs performed in 2026?

As of April 27, 2026, MDEV is down -10.01% year-to-date (YTD), while IDNA has returned 13.02%. That puts IDNA better performer ahead so far this year.

Which ETF is attracting more investor money: MDEV or IDNA?

Year-to-date, the MDEV ETF saw - in flows, compared to +$14M for IDNA.

Which ETF is more volatile: MDEV or IDNA?

Over the past year, MDEV had a volatility of 15.77%, while IDNA experienced 23.78%.

Which ETF is bigger: MDEV or IDNA?

As of April 27, 2026, MDEV holds $1.89 M in assets under management (AUM), while IDNA manages $161.27 M.

What sectors do the MDEV and IDNA ETFs invest in?

MDEV leans toward sectors like Health Care. Meanwhile, IDNA focuses on Health Care.

What are the top holdings of the MDEV ETF and IDNA ETF?

MDEV top holdings include GLOBUS MEDICAL, ALIGN TECHNOLOGY and PENUMBRA. IDNA holds in its top three: MODERNA INC, ARCELLX and IPSEN PROMESSES.

Which ETF is more diversified: MDEV or IDNA?

MDEV holds 48 securities with 37.53% of its assets in the top 15. IDNA has 51 securities and a top 15 weight of 64.09%.

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