MDEVvsIBBQETF Comparison
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First Trust Indxx Medical Devices ETF (MDEV) belongs to the Healthcare Technology segment. Invesco Nasdaq Biotechnology ETF (IBBQ) is part of the US Health Care segment. Both ETFs have the same top 3 sector exposures: and Healthcare. MDEV is more expensive with a Total Expense Ratio (TER) of 0.7%, versus 0.19% for IBBQ. MDEV is down -3.05% year-to-date (YTD) with +$994K in YTD flows. IBBQ performs better with 15.4% YTD performance, and +$3M in YTD flows. Run a side-by-side ETF comparison of MDEV and IBBQ below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.
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MDEV vs IBBQ performance and flow charts
Performance
Cumulative Flows
Historic performance and flows
Data as of 07/30/2026
| 1M | 3M | YTD | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|---|---|
| Perf. | MDEV IBBQ | +6.20%+0.10% | +9.77%+12.21% | -3.05%+15.40% | -0.45%+46.91% | -2.20%+62.42% | -23.17%+32.40% |
| Flows | MDEV IBBQ | +$994K+$4M | +$994K+$3M | +$994K+$3M | +$994K+$23M | +$767K+$39M | -$23M+$11M |
Volatility and drawdown
| 3M | 1Y | 3Y | 5Y | ||
|---|---|---|---|---|---|
| Volatility | MDEV IBBQ | +17.24%+22.34% | +16.50%+20.29% | +16.33%+20.25% | +19.16%+21.96% |
| Max drawdown | MDEV IBBQ | -3.88%-5.97% | -18.07%-8.38% | -21.75%-23.78% | -42.16%-38.09% |
| Max drawdown duration | MDEV IBBQ | 11d23d | 205d48d | 205d375d | 1787d1543d |
Trading data
MDEV | IBBQ | |
Last sale 7/31/2026 at 1:30 PM | $20.24 | $32.10 |
| Previous close 07/30/2026 | $20.16 | $32.70 |
| Consolidated volume 07/30/2026 | ||
| Average volume 30 days | ||
| Average discount or premium 30 days | ||
| Average Bid/Ask spread 30 days |
Replication quality
Data as of June 30, 2026
1-year trailing difference
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MDEV | IBBQ | |
|---|---|---|
| Tracking error | ||
| Tracking difference | ||
| 1 year cumulative return difference | ||
| Best | ||
| Worst | ||
| Daily return difference | ||
| Average | ||
| Worst | ||
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Main metrics
Last update 7/31/2026 at 1:30 PM
Live
Closed
MDEV | IBBQ | |
|---|---|---|
| Last price | $20.24 | $32.10 |
| 1D performance | +0.39% | -1.84% |
| AuM | $3.06 M | $76.45 M |
| E/R | 0.7% | 0.19% |
Characteristics
MDEV | IBBQ | |
|---|---|---|
| Management strategy | Passive | Passive |
| Provider | First Trust | Invesco |
| Benchmark | Indxx Global Medical Equipment Index | NASDAQ Biotechnology Index |
| N° of holdings | 47 | 251 |
| Asset class | Equities | Equities |
| Trailing 12m distribution yield | Join | Join |
| Inception date | June 23, 2021 | June 9, 2021 |
| ESG | No | No |
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Exposure
Countries
MDEV
USA
55.63%
Japan
7.86%
Other
36.51%
IBBQ
USA
88.1%
Other
11.9%
Sectors
MDEV
Healthcare
95.26%
Other
4.74%
IBBQ
Healthcare
99.98%
Other
0.02%
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Diversification
MDEV
Total weight of top 15 holdings out of 15
35.95%
IBBQ
Total weight of top 15 holdings out of 15
49.38%
Top 15 holdings
Data as of June 30, 2026
MDEV
West Pharmaceutical Services, Inc.
2.88%
Demant A/S
2.76%
LivaNova Plc
2.67%
Baxter International, Inc.
2.57%
Revvity, Inc.
2.55%
WuXi AppTec Co., Ltd.
2.41%
Waters Corp.
2.40%
Edwards Lifesciences Corp.
2.40%
Agilent Technologies, Inc.
2.36%
Teleflex, Inc.
2.23%
DexCom, Inc.
2.18%
Bio-Rad Laboratories, Inc.
2.16%
Sonova Holding AG
2.13%
Align Technology, Inc.
2.13%
Sysmex Corp.
2.12%
IBBQ
Vertex Pharmaceuticals, Inc.
8.16%
Amgen, Inc.
7.91%
Gilead Sciences, Inc.
7.07%
Regeneron Pharmaceuticals, Inc.
4.62%
Alnylam Pharmaceuticals, Inc.
2.76%
Revolution Medicines, Inc.
2.74%
Biogen, Inc.
2.26%
Illumina, Inc.
1.89%
Moderna, Inc.
1.89%
Royalty Pharma Plc
1.77%
Roivant Sciences Ltd.
1.74%
argenx SE
1.73%
United Therapeutics Corp.
1.63%
Incyte Corp.
1.61%
Insmed, Inc.
1.59%
Frequently asked questions about MDEV and IBBQ
How have the MDEV and IBBQ ETFs performed in 2026?
As of July 30, 2026, MDEV is down -3.05% year-to-date (YTD), while IBBQ has returned 15.4%. That puts IBBQ better performer ahead so far this year.
Which ETF is attracting more investor money: MDEV or IBBQ?
Year-to-date, the MDEV ETF saw +$994K in flows, compared to +$3M for IBBQ.
Which ETF is more volatile: MDEV or IBBQ?
Over the past year, MDEV had a volatility of 16.5%, while IBBQ experienced 20.29%.
Which ETF is bigger: MDEV or IBBQ?
As of July 30, 2026, MDEV holds $3.06 M in assets under management (AUM), while IBBQ manages $76.45 M.
What sectors do the MDEV and IBBQ ETFs invest in?
MDEV leans toward sectors like Healthcare. Meanwhile, IBBQ focuses on Healthcare.
What are the top holdings of the MDEV ETF and IBBQ ETF?
MDEV top holdings include West Pharmaceutical Services, Inc., Demant A/S and LivaNova Plc. IBBQ holds in its top three: Vertex Pharmaceuticals, Inc., Amgen, Inc. and Gilead Sciences, Inc..
Which ETF is more diversified: MDEV or IBBQ?
MDEV holds 47 securities with 35.95% of its assets in the top 15. IBBQ has 251 securities and a top 15 weight of 49.38%.
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