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LFSCvsXHEETF Comparison

ETF 1

LFSC

F/m Emerald Life Sciences Innovation ETF

This fund is part of

Life Sciences

-0.51%

Full LFSC fund page

VS

ETF 2

XHE

State Street SPDR S&P Health Care Equipment ETF

This fund is part of

US Health Care

+0.15%

Full XHE fund page

F/m Emerald Life Sciences Innovation ETF (LFSC) belongs to the Life Sciences segment. State Street SPDR S&P Health Care Equipment ETF (XHE) is part of the US Health Care segment. LFSC's top 3 sector exposures are Healthcare and Sovereign. In contrast, XHE's top sector exposures are Healthcare and Finance. LFSC is more expensive with a Total Expense Ratio (TER) of 0.79%, versus 0.35% for XHE. LFSC is up 23.23% year-to-date (YTD) with +$8M in YTD flows. XHE performs worse with -3.33% YTD performance, and +$4M in YTD flows. Run a side-by-side ETF comparison of LFSC and XHE below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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LFSC vs XHE performance and flow charts

Performance

Cumulative Flows

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Data Services

Historic performance and flows

Data as of 07/24/2026

		1M	3M	YTD	1Y	3Y	5Y
Perf.	LFSC XHE	+4.17%+5.83%	+20.39%+2.12%	+23.23%-3.33%	+82.30%+9.18%	n/a-12.44%	n/a-32.06%
Flows	LFSC XHE	+$2M+$6M	+$3M+$4M	+$8M+$4M	+$17M-$15M	--$377M	--$395M

Volatility and drawdown

		3M	1Y	3Y	5Y
Volatility	LFSC XHE	+26.23%+26.32%	+26.91%+22.80%	n/a+22.21%	n/a+24.71%
Max drawdown	LFSC XHE	-6.53%-7.15%	-16.25%-18.20%	n/a-32.21%	n/a-49.90%
Max drawdown duration	LFSC XHE	20d63d	168d195d	n/a1092d	n/a1784d

Trading data

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	LFSC	XHE
Last sale 7/24/2026 at 1:30 PM	$45.10	$85.18
Previous close 07/23/2026	$45.46	$85.02
Consolidated volume 07/23/2026
Average volume 30 days
Average discount or premium 30 days
Average Bid/Ask spread 30 days

Replication quality

Data as of June 30, 2026

1-year trailing difference

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LFSC

is actively managed and doesn’t replicate an index

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	LFSC	XHE
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst

Main metrics

Last update 7/24/2026 at 1:30 PM

Live

Closed

	LFSC	XHE
Last price	$45.10	$85.18
1D performance	-0.79%	+0.19%
AuM	$123.48 M	$153.34 M
E/R	0.79%	0.35%

Characteristics

	LFSC	XHE
Management strategy	Active	Passive
Provider	Emerald Group	State Street Investment Management
Benchmark	-	S&P Health Care Equipment Select Industry Index
N° of holdings	40	67
Asset class	-	Equities
Trailing 12m distribution yield	Join	Join
Inception date	October 31, 2024	January 26, 2011
ESG	No	No

More LFSC data on Trackinsight

More XHE data on Trackinsight

Exposure

Countries

LFSC

USA

90.9%

United Kingdom

7.04%

Other

2.06%

XHE

USA

89.54%

Other

10.46%

Sectors

LFSC

Healthcare

98.03%

Other

1.97%

XHE

Healthcare

94.54%

Other

5.46%

Diversification

LFSC

Total weight of top 15 holdings out of 15

73.24%

XHE

Total weight of top 15 holdings out of 15

26.73%

Top 15 holdings

Data as of June 30, 2026

LFSC

Travere Therapeutics, Inc.

8.37%

Cogent Biosciences, Inc.

7.18%

LivaNova Plc

7.04%

Spyre Therapeutics, Inc.

6.71%

Guardant Health, Inc.

5.56%

Corcept Therapeutics, Inc.

5.27%

Mirum Pharmaceuticals, Inc.

5.25%

BillionToOne, Inc.

4.25%

Cytokinetics, Inc.

4.13%

Veradermics, Inc.

3.76%

United Therapeutics Corp.

3.55%

Trevi Therapeutics, Inc.

3.50%

Savara, Inc.

3.20%

Dianthus Therapeutics, Inc.

2.77%

Nektar Therapeutics

2.70%

XHE

Butterfly Network, Inc.

2.45%

QuidelOrtho Corp.

2.04%

Glaukos Corp.

1.79%

UFP Technologies, Inc.

1.79%

Axogen, Inc.

1.76%

Lantheus Holdings, Inc.

1.74%

Artivion, Inc.

1.73%

Envista Holdings Corp.

1.72%

Omnicell, Inc.

1.71%

Medline, Inc.

1.69%

Alphatec Holdings, Inc.

1.67%

Dentsply Sirona, Inc.

1.66%

Inspire Medical Systems, Inc.

1.66%

The Cooper Cos., Inc.

1.66%

Edwards Lifesciences Corp.

1.65%

Frequently asked questions about LFSC and XHE

How have the LFSC and XHE ETFs performed in 2026?

As of July 24, 2026, LFSC is up 23.23% year-to-date (YTD), while XHE has lost -3.33%. That puts LFSC better performer ahead so far this year.

Which ETF is attracting more investor money: LFSC or XHE?

Year-to-date, the LFSC ETF saw +$8M in flows, compared to +$4M for XHE.

Which ETF is more volatile: LFSC or XHE?

Over the past year, LFSC had a volatility of 26.91%, while XHE experienced 22.8%.

Which ETF is bigger: LFSC or XHE?

As of July 24, 2026, LFSC holds $123.48 M in assets under management (AUM), while XHE manages $153.34 M.

What sectors do the LFSC and XHE ETFs invest in?

LFSC leans toward sectors like Healthcare. Meanwhile, XHE focuses on Healthcare.

What are the top holdings of the LFSC ETF and XHE ETF?

LFSC top holdings include Travere Therapeutics, Inc., Cogent Biosciences, Inc. and LivaNova Plc. XHE holds in its top three: Butterfly Network, Inc., QuidelOrtho Corp. and Glaukos Corp..

LFSCvsXHEETF Comparison

F/m Emerald Life Sciences Innovation ETF

State Street SPDR S&P Health Care Equipment ETF

LFSC vs XHE performance and flow charts

Performance

Cumulative Flows

Get all the metrics on this page, and more, through a reliable ETF data feed

Countries

Sectors

Diversification

Top 15 holdings

How have the LFSC and XHE ETFs performed in 2026?

As of July 24, 2026, LFSC is up 23.23% year-to-date (YTD), while XHE has lost -3.33%. That puts LFSC better performer ahead so far this year.

Which ETF is attracting more investor money: LFSC or XHE?

Year-to-date, the LFSC ETF saw +$8M in flows, compared to +$4M for XHE.

Which ETF is more volatile: LFSC or XHE?

Over the past year, LFSC had a volatility of 26.91%, while XHE experienced 22.8%.

Which ETF is bigger: LFSC or XHE?

As of July 24, 2026, LFSC holds $123.48 M in assets under management (AUM), while XHE manages $153.34 M.

What sectors do the LFSC and XHE ETFs invest in?

LFSC leans toward sectors like Healthcare. Meanwhile, XHE focuses on Healthcare.

What are the top holdings of the LFSC ETF and XHE ETF?

LFSC top holdings include Travere Therapeutics, Inc., Cogent Biosciences, Inc. and LivaNova Plc. XHE holds in its top three: Butterfly Network, Inc., QuidelOrtho Corp. and Glaukos Corp..

Which ETF is more diversified: LFSC or XHE?

LFSC holds 40 securities with 73.24% of its assets in the top 15. XHE has 67 securities and a top 15 weight of 26.73%.

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