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IYHvsXLVIETF Comparison

ETF 1
IYH

iShares U.S. Healthcare ETF

This fund is part of
US Health Care
-0.3%
Full IYH fund page
VS
ETF 2
XLVI

The Health Care Select Sector SPDR Premium Income Fund

This fund is part of
Options Strategies
-0.04%
Full XLVI fund page

iShares U.S. Healthcare ETF (IYH) belongs to the US Health Care segment. The Health Care Select Sector SPDR Premium Income Fund (XLVI) is part of the Options Strategies segment. Both ETFs have the same top 3 sector exposures: and Health Care. IYH is more expensive with a Total Expense Ratio (TER) of 0.38%, versus 0.35% for XLVI. IYH is down -1.84% year-to-date (YTD) with -$496M in YTD flows. XLVI performs better with 0.28% YTD performance, and +$2M in YTD flows. Run a side-by-side ETF comparison of IYH and XLVI below, and assess how they stack up in performance, liquidity, risk, exposure, holdings, and more, helping you select the best ETF for your investments.

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IYH vs XLVI performance and flow charts

Performance

-2.0-1.00.01.02.0%Feb 11Feb 19Feb 26Mar 5

Cumulative Flows

-300,000,000-200,000,000-100,000,0000100,000,000Feb 11Feb 19Feb 26Mar 5

Get all the metrics on this page, and more, through a reliable ETF data feed

Daily, global ETF data for advanced analysis or integration into apps (API), from our partner Trackinsight.

Historic performance and flows
Data as of 03/11/2026
1M3MYTD1Y3Y5Y
Perf.
IYH
XLVI
-2.08%-1.07%
-0.90%+1.89%
-1.84%+0.28%
+6.00%n/a
+25.78%n/a
+36.39%n/a
Flows
IYH
XLVI
-$245M+$788K
-$580M+$3M
-$496M+$2M
-$318M-
-$643M-
-$164M-
Volatility and drawdown
3M1Y3Y5Y
Volatility
IYH
XLVI
+13.70%+10.15%
+17.71%n/a
+13.80%n/a
+14.71%n/a
Max drawdown
IYH
XLVI
-5.23%-3.26%
-12.43%n/a
-17.89%n/a
-17.89%n/a
Max drawdown duration
IYH
XLVI
63d10d
211dn/a
445dn/a
445dn/a
Trading data

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IYH
XLVI
Last sale
3/11/2026 at 1:30 PM
$63.88
$25.92
Previous close
03/11/2026
$64.05
$25.98
Consolidated volume
03/11/2026
Average volume
30 days
Average discount or premium
30 days
Average Bid/Ask spread
30 days
Replication quality
Data as of February 27, 2026
1-year trailing difference

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XLVI
is actively managed and doesn’t replicate an index

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IYH
XLVI
Tracking error
Tracking difference
1 year cumulative return difference
Best
Worst
Daily return difference
Average
Worst
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Main metrics
Last update 3/11/2026 at 1:30 PM
Live
Closed
IYH
XLVI
Last price
$63.88
$25.92
1D performance
-0.27%
-0.23%
AuM$3.02 B$13.24 M
E/R0.38%0.35%
Characteristics
IYH
XLVI
Management strategyPassiveActive
ProvideriSharesSPDR
BenchmarkRussell 1000 Health Care RIC 22.5/45 Capped Gross Index-
N° of holdings9657
Asset classEquities-
Trailing 12m distribution yield
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Inception dateJune 12, 2000July 30, 2025
ESGNoNo
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Exposure

Countries

IYH
USA
96.45%
Other
3.55%
XLVI
USA
96.37%
Other
3.63%

Sectors

IYH
Health Care
97.98%
Other
2.02%
XLVI
Health Care
97.65%
Other
2.35%
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Diversification

IYH

Total weight of top 15 holdings out of 15

67.75%
XLVI

Total weight of top 15 holdings out of 15

69.69%

Top 15 holdings

Data as of January 31, 2026
IYH
LILLY
14.19%
JOHNSON&JOHNSON
9.46%
ABBVIE
6.76%
MERCK & CO INC
4.72%
UNITEDHEALTH GRP
4.60%
THERMO FISHER SCIENTIFIC
3.87%
AMGEN-T
3.19%
ABBOTT LABS
3.18%
INTUITIVE SURGICAL
3.10%
GILEAD SCIENCES
3.01%
PFIZER
2.57%
DANAHER
2.39%
BOSTON SCIENTIFIC
2.36%
MEDTRONIC PLC
2.24%
VERTEX PHARMACEUTICALS
2.12%
XLVI
LILLY
14.60%
JOHNSON&JOHNSON
9.71%
ABBVIE
6.99%
MERCK & CO INC
4.85%
UNITEDHEALTH GRP
4.61%
THERMO FISHER SCIENTIFIC
3.85%
ABBOTT LABS
3.37%
AMGEN-T
3.26%
INTUITIVE SURGICAL
3.17%
GILEAD SCIENCES
3.12%
PFIZER
2.66%
BOSTON SCIENTIFIC
2.46%
DANAHER
2.44%
MEDTRONIC PLC
2.34%
STRYKER
2.25%
Frequently asked questions about IYH and XLVI

How have the IYH and XLVI ETFs performed in 2026?

As of March 11, 2026, IYH is down -1.84% year-to-date (YTD), while XLVI has returned 0.28%. That puts XLVI better performer ahead so far this year.

Which ETF is attracting more investor money: IYH or XLVI?

Year-to-date, the IYH ETF saw -$496M in flows, compared to +$2M for XLVI.

Which ETF is bigger: IYH or XLVI?

As of March 11, 2026, IYH holds $3.02 B in assets under management (AUM), while XLVI manages $13.24 M.

What sectors do the IYH and XLVI ETFs invest in?

IYH leans toward sectors like Health Care. Meanwhile, XLVI focuses on Health Care.

What are the top holdings of the IYH ETF and XLVI ETF?

IYH top holdings include LILLY, JOHNSON&JOHNSON and ABBVIE. XLVI holds in its top three: LILLY, JOHNSON&JOHNSON and ABBVIE.

Which ETF is more diversified: IYH or XLVI?

IYH holds 104 securities with 67.75% of its assets in the top 15. XLVI has 60 securities and a top 15 weight of 69.69%.

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